Find clinical trials for ALS. Search for ALS clinical trials in different cities and states across the United States.
Sponsor:
MD Stem Cells
Location:
Code:
NCT02795052
Conditions
Neurologic Disorders
Nervous System Diseases
Neurodegenerative Diseases
Neurological Disorders
Stroke
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Intravenous and Intranasal BMSC
Sponsor:
Massachusetts General Hospital
Location:
Code:
NCT05966038
Conditions
ALS
PLS
MND (Motor Neurone DIsease)
Kennedy Disease
PMA - Progressive Muscular Atrophy
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Sponsor:
New York Stem Cell Foundation Research Institute
Location:
Code:
NCT06203106
Conditions
ALS
Amyotrophic Lateral Sclerosis
Alzheimer Disease
Alzheimer Disease, Early Onset
Alzheimer Disease, Late Onset
Eligibility Criteria
Sex: All
Age: 30+
Healthy Volunteers: Not accepted
Interventions
Biological Sample Collection
Sponsor:
Leigh R. Hochberg, MD, PhD.
Location:
Code:
NCT06511934
Conditions
Brainstem Stroke
ALS
Tetraplegia
Spinal Cord Injuries
Cervical Spinal Cord Injury
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
BrainGate Neural Interface System
Sponsor:
Karunesh Ganguly
Location:
Code:
NCT03698149
Conditions
ALS
SCI - Spinal Cord Injury
Stroke
Multiple Sclerosis
Muscular Dystrophies
Eligibility Criteria
Sex: All
Age: 21+
Healthy Volunteers: Not accepted
Interventions
PMT/Blackrock Combination Device
Sponsor:
University of Minnesota
Location:
Code:
NCT06735014
Conditions
Amyotrophic Lateral Sclerosis
ALS
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Magnetic Resonance Imaging
Plasma neurofilament light chain (NfL) quantification
Sponsor:
University of Florida
Location:
Code:
NCT05377424
Conditions
ALS
Eligibility Criteria
Sex: All
Age: 21 - 70+
Healthy Volunteers: Accepted
Interventions
Consume 20mg of istradefylline
Low Oxygen therapy
Placebo counterpart to the istradefylline drug
SHAM counterpart to low oxygen therapy.
Sponsor:
Riverview Health Centre
Location:
Code:
NCT04138095
Conditions
Cancer
Heart Failure
Copd
ALS
Eligibility Criteria
Sex: All
Age: 0 - 70+
Healthy Volunteers: Not accepted
Interventions
Virtual Reality
Sponsor:
Nova Southeastern University
Location:
Code:
NCT05913882
Conditions
ALS
Respiratory Insufficiency
Dysphagia
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
Respiratory Muscle Strength Training (LVR+EMST)
Sponsor:
University of Calgary
Location:
Code:
NCT03272503
Conditions
ALS
Amyotrophic Lateral Sclerosis
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Pimozide 2mg/day (current) or 4 mg/day (study initiation)
Placebo Oral Tablet
Amyotrophic Lateral Sclerosis (ALS) clinical trials are research studies conducted to explore and evaluate new treatments, therapies, and diagnostic tools for ALS, commonly known as Lou Gehrig’s disease. These trials are crucial in the search for effective ways to slow the progression of the disease, manage symptoms, and ultimately find a cure for ALS.
Clinical trials are essential in ALS research as they are the primary method for testing new treatments and interventions. They help in understanding the effectiveness and safety of these treatments in humans. Through these trials, researchers can uncover new insights into the disease, leading to improved care, symptom management, and potentially life-extending therapies for those affected by ALS.
These trials can vary based on the type of intervention being studied, the phase of development, and the specific objectives of the trial. Some common types of ALS clinical trials are:
These trials focus on finding new ways to alleviate the symptoms associated with ALS, such as muscle weakness, difficulty speaking, and respiratory issues. They test new medications, physical therapies, and other interventions aimed at improving the quality of life for individuals living with ALS.
Disease-modifying trials aim to discover treatments that can alter the course of ALS. These include studies on drugs that could potentially slow down or halt the progression of the disease, providing hope for extending the lives of ALS patients.
Supportive care and rehabilitation trials test interventions designed to support the overall well-being of ALS patients. They include studies on rehabilitation techniques, adaptive equipment, and strategies to assist with daily activities, focusing on maintaining independence and enhancing quality of life.
Emerging therapy trials explore the potential of groundbreaking treatments such as gene therapy, stem cell treatment, and innovative medical devices. These studies represent the cutting-edge of ALS research, seeking novel ways to tackle the disease.
Innovations in ALS treatment through clinical trials are making significant progress in several key areas. One major area is the development of new medications and drug therapies. These trials involve detailed testing of new drugs to see how they affect ALS progression and symptoms.
Another area of research is neuroprotective strategies, which aim to protect nerve cells from damage and slow down the disease's progression, using various medications and supplements.
Additionally, clinical trials are looking into the effects of diet and lifestyle changes on ALS. These studies are testing different dietary supplements and lifestyle adjustments to see if they can help manage ALS and improve patients' quality of life.
Individuals diagnosed with ALS are typically eligible to participate in clinical trials. Each trial has specific inclusion criteria, which might include the stage of the disease, overall health status, and previous treatment history. Some trials might also be open to individuals without ALS for observational or preventative studies, or to compare health outcomes.
Participating in an ALS clinical trial typically involves a pre-screening process, informed consent, and baseline health assessments. Participants are often randomized into treatment or control groups and undergo the trial's therapy while being closely monitored for effectiveness and side effects. Regular medical check-ups and tests are conducted throughout the trial to track the disease's progression. Participants are required to adhere to specific trial protocols and have the right to withdraw at any time.
Unsure about participating in a clinical trial? Dive into our comprehensive guide to learn about the process, benefits, and potential impact of your involvement. Get the facts you need to make an informed decision today!
Enrolling in a clinical trial for ALS through our platform is a straightforward and user-friendly process. Here's how to get started: