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COPD Clinical Trials

Find clinical trials for COPD. Search for COPD clinical trials in different cities and states across the United States.

COPD
e.g. MassachusettsHealthy volunteers: No

Efficacy and Safety of Tozorakimab in Symptomatic Chronic Obstructive Pulmonary Disease With a History of Exacerbations

Recruiting
PHASE3

Sponsor:

AstraZeneca

Location:

Birmingham, Decatur, Sheffield, Peoriashow 76 more

Code:

NCT06040086

Conditions

Chronic Obstructive Pulmonary Disease (COPD)

Eligibility Criteria

Sex: All

Age: 40 - 70+

Healthy Volunteers: Not accepted

Interventions

Placebo

Tozorakimab

Mitochondrial Derived Reactive Oxygen Species on Cardiovascular Health in Chronic Obstructive Pulmonary Disease (COPD)

Recruiting
EARLY_PHASE1

Sponsor:

Virginia Commonwealth University

Location:

Richmond

Code:

NCT05605548

Conditions

Chronic Obstructive Pulmonary Disease

Eligibility Criteria

Sex: All

Age: 40+

Healthy Volunteers: Not accepted

Interventions

MitoQ

Placebo

Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU

Recruiting

Sponsor:

Brigham and Women's Hospital

Location:

Boston

Code:

NCT06538376

Conditions

Pulmonary Edema

Pneumonia

Atelectasis

Pleural Effusion

Acute Rejection of Lung Transplant (Disorder)

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Portable Dynamic Digital Radiography (DDR)

Efficacy and Safety of Tozorakimab in Symptomatic Chronic Obstructive Pulmonary Disease With a History of Exacerbations

Recruiting
PHASE3

Sponsor:

AstraZeneca

Location:

Huntsville, Mobile, Montgomery, Tempeshow 54 more

Code:

NCT05166889

Conditions

Chronic Obstructive Pulmonary Disease (COPD)

Eligibility Criteria

Sex: All

Age: 40 - 70+

Healthy Volunteers: Not accepted

Interventions

Tozorakimab

Placebo

Safety, PK and PD Relationships of RLS-0071 in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Recruiting
PHASE2

Sponsor:

ReAlta Life Sciences, Inc.

Location:

Philadelphia

Code:

NCT06175065

Conditions

Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Eligibility Criteria

Sex: All

Age: 30+

Healthy Volunteers: Not accepted

Interventions

RLS-0071

Placebo

Recruiting

Sponsor:

0

Eligibility Criteria

Sex:

Age: 0 - 70+

Healthy Volunteers: Not accepted

Multi-Center Clean Air Randomized Controlled Trial in COPD

Recruiting
PHASE3

Sponsor:

JHSPH Center for Clinical Trials

Location:

Birmingham, Los Angeles, Iowa City, Baltimoreshow 4 more

Code:

NCT06376994

Conditions

Chronic Obstructive Pulmonary Disease (COPD)

Eligibility Criteria

Sex: All

Age: 40+

Healthy Volunteers: Not accepted

Interventions

Air cleaner

Sham air cleaner

An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients with Severe Emphysema

Recruiting

Sponsor:

Pulmonx Corporation

Location:

Detroit, Philadelphia, Philadelphia

Code:

NCT06035120

Conditions

Emphysema, Pulmonary

Emphysema or COPD

Eligibility Criteria

Sex: All

Age: 22 - 70+

Healthy Volunteers: Not accepted

Interventions

AeriSeal System

The Effect of a Technology-Mediated Integrated Walking and Tai Chi Intervention on Physical Function in Veterans With COPD and Chronic Musculoskeletal Pain

Recruiting

Sponsor:

VA Office of Research and Development

Location:

Boston

Code:

NCT05701982

Conditions

COPD

Chronic Musculoskeletal Pain

Eligibility Criteria

Sex: All

Age: 40 - 70+

Healthy Volunteers: Not accepted

Interventions

Every Step Counts-Tai Chi

Usual Care

Lung and Bone Marrow Transplantation for Lung and Bone Marrow Failure

Recruiting
PHASE1
PHASE2

Sponsor:

Paul Szabolcs

Location:

Pittsburgh, Pittsburgh

Code:

NCT03500731

Conditions

Idiopathic Pulmonary Fibrosis

Emphysema or COPD

Eligibility Criteria

Sex: All

Age: 18 - 60

Healthy Volunteers: Not accepted

Interventions

CD3/CD19 negative hematopoietic stem cells

Rituximab

Alemtuzumab

Fludarabine

Thiotepa

What are COPD clinical trials?

COPD clinical trials are research studies aimed at evaluating new treatments, interventions, or management strategies for Chronic Obstructive Pulmonary Disease (COPD). These trials aim to discover more effective ways to alleviate symptoms, slow disease progression, and improve the quality of life for individuals living with COPD.

The importance of clinical trials in COPD research

Clinical trials play a vital role in COPD research, offering the most reliable method to test the safety and effectiveness of new therapies. Through these studies, researchers can identify better ways to manage COPD, uncover insights into its pathophysiology, and potentially find a cure.

Types of COPD clinical trials

Types of COPD clinical trials include a wide range of studies focused on improving treatment and management of the disease. These trials test new medications and inhaler technologies, assess physical therapy and rehabilitation programs, explore oxygen and ventilatory support options, evaluate the effectiveness of surgical and interventional procedures, and examine lifestyle and behavioral changes. Each type of trial aims to find better ways to manage COPD symptoms, enhance patient quality of life, and slow disease progression.

Trials focused on medication and inhaler therapies

These trials evaluate new drugs or combinations of medications administered through inhalers, aiming to reduce the frequency of COPD flare-ups, improve lung function, and alleviate symptoms. They often explore the efficacy of bronchodilators, corticosteroids, and other pharmacological treatments in managing COPD.

Physical therapy and rehabilitation trials

Rehabilitation trials investigate the benefits of physical therapy programs, including exercises designed to enhance respiratory function, increase stamina, and improve overall physical fitness in COPD patients. These studies assess how rehabilitation impacts the quality of life, exercise tolerance, and disease progression.

Oxygen and ventilatory support trials

These studies explore the effectiveness of supplemental oxygen therapy and mechanical ventilatory support in individuals with COPD, particularly those with severe disease. Trials may investigate the optimal timing, delivery methods, and outcomes of using oxygen therapy and non-invasive ventilation to manage chronic respiratory failure.

Surgical and interventional procedures trials

Trials exploring surgical and interventional procedures assess the outcomes of surgical and minimally invasive procedures, such as lung volume reduction surgery (LVRS), bullectomy, or endobronchial valve placement. These studies aim to determine how well these interventions improve breathing, reduce symptoms, and enhance the quality of life for patients with advanced COPD.

Lifestyle and behavioral modification trials

Lifestyle and behavioral modification trials examine the impact of dietary changes, smoking cessation, stress management and other lifestyle interventions on COPD management. They investigate how behavioral interventions can affect disease progression, symptom control, and overall well-being.

Who can participate in COPD clinical trials?

Individuals diagnosed with COPD at various stages of the disease may be eligible to participate in clinical trials. Eligibility criteria vary depending on the study's objectives and may include factors like age, smoking history, severity of COPD, and current treatments. Some trials may specifically seek participants with certain COPD characteristics or those who have not responded to standard treatments.

What to expect in a COPD trial

Participants in a COPD clinical trial can expect a comprehensive process that begins with eligibility screening and informed consent. During the trial, participants may receive new treatments or interventions and undergo regular monitoring, including medical assessments, lung function tests, and questionnaires about their symptoms and quality of life. Trials are conducted under strict safety protocols, with participants' health and well-being as the top priority.

How to enroll in a COPD clinical trial

Enrolling in a COPD clinical trial through our platform is a straightforward and user-friendly process. Here's how to get started:

  1. Identify Your Trial: Use our intuitive search bar or filter options to locate clinical trials specific to requirements. This first step simplifies the process of finding relevant research studies tailored to your needs.
  2. Select Your Preferred Location: To find trials conveniently located near you, simply input your preferred location into the dedicated filter bar on the left-hand side of the page.
  3. Explore Study Details: For in-depth information about each study, simply click the “Learn More” button. This will provide you with comprehensive details about the trial, including objectives, procedures, and eligibility criteria.
  4. Complete the Health Profile: After clicking on the “Get started” button you will be taken to our efficient 5-step application process to provide important health information. This helps us match you with the clinical trial that best fits your needs.
  5. Submit the Application: After completing the application, send it in. A clinical trial coordinator will review it and contact you regarding the possibility of participation.