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Vaccines Clinical Trials

Find clinical trials for vaccines. Search for vaccines clinical trials in different cities and states across the United States.

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FeaturedActive & Responsive

Bone Marrow and Peripheral Blood Immune Responses Study

for
Influenza
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18 - 64

Code: NCT05616546

Recruiting
FeaturedActive & Responsive

A Surveillance Study of Susceptibility to Baloxavir Marboxil in Pediatric Participants With Influenza and Transmission of Influenza to Household Contacts

for
Influenza
Location: Miami FL, Smithfield PA, Middleburg Heights OH,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 0 - 11

Code: NCT06094010

Phase3, Recruiting
Featured

RO7771950 Versus Tucatinib in Combination With Trastuzumab and Capecitabine in People With Locally Advanced or Metastatic Breast Cancer That is Human Epidermal Growth Factor Receptor 2 (HER2)-Positive

for
HER2-positive Breast Cancer
Location: Shirley NY, Quebec, Albany NY, East Brunswick NJ,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07413939

Phase2, Phase3, Recruiting
Active & Responsive

Addressing Unfunded Vaccines Through a Co-payment Mechanism in Pharmacies

for
Preventable Disease, Vaccine
Location: Halifax
Sponsor: Canadian Immunization Research Network

Sex: All

Age: 2+

Code: NCT06489964

Recruiting
Active & Responsive

HER2 Vaccine for Locally Advanced Breast Cancer

for
Breast Cancer, HER2-positive Breast Cancer
Location: Indianapolis IN
Sponsor: Pravin T.P Kaumaya

Sex: All

Age: 18+

Code: NCT06949410

Phase1, Recruiting

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Active & Responsive

TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer

for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT06868433

Phase1, Recruiting
Active & Responsive

HER-2 B Cell Peptide Vaccine

for
Metastatic Breast Cancer, HER2-positive Breast Cancer,
Location: Indianpolis IN
Sponsor: Pravin T.P Kaumaya

Sex: All

Age: 18+

Code: NCT06414733

Phase1, Recruiting
Active & Responsive

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

for
Clinical Stage III Cutaneous Melanoma AJCC v8,
Location: Springfield MA, Saint Johnsbury VT, Lebanon NH,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05136196

Phase2, Recruiting
Active & Responsive

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

for
Metastatic Head and Neck Squamous Cell Carcinoma,
Location: Boston MA, Saint Johnsbury VT, Lebanon NH, Commack NY,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06589804

Phase3, Recruiting
Active & Responsive

The Natural History of Severe Viral Infections and Characterization of Immune Defects in Patients Without Known Immunocompromise

for
EBV, HSV, VZV, HPV, CMV
Location: Bethesda MD
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 2 - 70+

Code: NCT01011712

Recruiting
Active & Responsive

Influenza Human Challenge Model

for
Influenza
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18 - 49

Code: NCT05332899

Phase1, Recruiting
Active & Responsive

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

for
Ampulla of Vater Carcinoma, Appendix Carcinoma,
Location: Damariscotta ME, Brunswick ME, Scarborough ME,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT07283939

Recruiting
Active & Responsive

First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer

for
PIK3CA Mutation, Solid Tumor, Adult,
Location: Boston MA, New Haven CT, New York NY, New Brunswick NJ,
Sponsor: Relay Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05216432

Phase1, Recruiting
Active & Responsive

A/Texas Flu Challenge

for
Influenza
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18 - 49

Code: NCT06753474

Phase1, Recruiting
Active & Responsive

Systems Investigation of Vaccine Responses in Aging and Frailty

for
Influenza
Location: New Haven CT
Sponsor: Yale University

Sex: All

Age: 21+

Code: NCT05291676

Phase2, Recruiting
Active & ResponsiveNew

A Study to Evaluate Efficacy, Safety, and Tolerability of Remibrutinib in Adult Participants With Severe Chronic Pruritus of Unknown Origin (CPUO)

for
Chronic Pruritus of Unknown Origin
Location: Brighton MA, Tampa FL, Mayfield Heights OH,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07811869

Phase3, Recruiting
Active & ResponsiveNew

CASCADE 2002: PROTECT Study, "PRObiotics to TrEat Anal preCancer Trial

for
HSIL, High Grade Squamous Intraepithelial Lesion,
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 21+

Code: NCT06949800

Phase2, Recruiting
Active & ResponsiveNew

Patient Navigation for HER2+ Metastatic Breast Cancer Patients Treated With Tucatinib

for
HER2+ Metastatic Breast Cancer (MBC)
Location: Durham NC
Sponsor: Duke University

Sex: Female

Age: 18+

Code: NCT06983691

Recruiting
Active & Responsive

A Study of a Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumors

for
Advanced Solid Tumor, Adult, ERBB2 Altered Breast Cancer,
Location: New Haven CT, Lake Success NY, New York NY, Fairfax VA,
Sponsor: Cogent Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT07361562

Phase1, Recruiting
Active & Responsive

A Phase II Evaluation of Afatinib in Patients With Persistent or Recurrent HER2-positive Uterine Serous Carcinoma

for
HER2/Neu+ Uterine Serous Carcinoma
Location: New Haven CT
Sponsor: Yale University

Sex: Female

Age: 18 - 70+

Code: NCT02491099

Phase2, Recruiting

What are vaccine clinical trials?

Vaccine clinical trials are research studies conducted to evaluate the safety, efficacy, and immunogenicity (the ability to provoke an immune response) of vaccines aimed at preventing diseases. These trials are crucial for developing new vaccines against various conditions, including infectious diseases, cancers, and chronic conditions.

Importance of clinical trials for vaccines

Clinical trials for vaccines play a vital role in ensuring that new vaccines are both safe and effective before they are made available to the public. These trials help identify the best dosing schedules, understand how the immune system responds to the vaccine, and determine any potential side effects. They are fundamental in the fight against emerging infectious diseases, as well as in the development of therapeutic vaccines for conditions like cancer.

Types of interventions studied in vaccine clinical trials

Eligibility and participation in vaccine clinical trials

How to enroll in a vaccine clinical trial