IVF Clinical Trials

Success depends heavily on age. In CDC data for 2022, about half of egg retrievals in women under 35 using their own eggs led to a live birth, about 36 percent at ages 35 to 37, about 23 percent at 38 to 40, and under 8 percent over 40. Across all ages, roughly 4 in 10 embryo transfers resulted in a live birth. IVF trials use these same endpoints, live birth per transfer or per retrieval, rather than pregnancy tests, because that is the outcome that matters to families. It is also why an IVF study takes time: the answer arrives nine months after the transfer. The CDC publishes clinic level rates and a success estimator that uses national data.

New to research? Read how informed consent works.

Informed Consent in Clinical Trials: What Is It and How It’s Obtained

One cycle typically runs a few weeks from the first injection to the transfer, followed by about two weeks before a pregnancy test. Many people need more than one cycle, and frozen transfers add time.

Ovarian stimulation with hormone injections, egg retrieval under sedation, fertilization in the lab, embryo culture for several days, and embryo transfer into the uterus. Many cycles add a sixth step, freezing extra embryos for later.

Almost all IVF trials enroll people who are already planning or undergoing an IVF cycle at the study clinic, usually within an age range such as 18 to 42, and often with a specific situation: a first cycle, a frozen transfer, diminished ovarian reserve, or PCOS. Many require a normal uterus on ultrasound and exclude certain medical conditions. Some studies randomize between two standard approaches, so both groups receive real treatment; others add a study medicine or a placebo to the usual protocol. Partners may be enrolled too in studies of sperm or of the couple's experience. Eligibility always varies by study, and our guide explains how eligibility criteria work.

Enrolling in an IVF clinical trial through our platform is a straightforward and user-friendly process. Here's how to get started:

1. Identify Your Trial: Use our search tool or filters to find IVF clinical trials that match your specific fertility needs or interests. This step simplifies the process of finding relevant research studies tailored to your requirements.
2. Select Your Preferred Location: To find trials conveniently located near you, simply input your preferred location into the dedicated filter bar on the left-hand side of the page.
3. Explore Study Details: For in-depth information about each study, simply click the “Learn More” button. This will provide you with comprehensive details about the trial, including objectives, procedures, and eligibility criteria.
4. Complete the Health Profile: After clicking on the “Get started” button you will be taken to our efficient 5-step application process to provide important health information. This helps us match you with the clinical trial that best fits your needs.
5. Submit the Application: After completing the application, send it in. A clinical trial coordinator will review it and contact you regarding the possibility of participation.