Oncology Clinical Trials
Find clinical trials for oncology. Search for oncology clinical trials in different cities and states across the United States.
MyeloMATCHComparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)
Sponsor:
National Cancer Institute (NCI)
Location:
Code:
NCT06672146
Conditions
Acute Myeloid Leukemia
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Biospecimen Collection
Bone Marrow Aspiration
Bone Marrow Biopsy
Decitabine and Cedazuridine
Enasidenib
18F-DCFPyL18F-DCFPyL Imaging as a Method to Assess Treatment Response to Stereotactic Body Radiation Therapy
Sponsor:
National Cancer Institute (NCI)
Location:
Code:
NCT05155046
Conditions
Localized Prostate Cancer
Eligibility Criteria
Sex: Male
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
18F-DCFPyL
DaratumumabDaratumumab Maintenance Therapy for Improving Survival in Patients With Light Chain Amyloidosis, EMILIA Trial
Sponsor:
Mayo Clinic
Location:
Code:
NCT05898646
Conditions
AL Amyloidosis
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Bone Marrow Aspiration
Daratumumab
Echocardiography
Questionnaire Administration
X-Ray Imaging
ImmunotherapyImmunotherapy Before and After Surgery for Treatment of Recurrent or Progressive High Grade Glioma in Children and Young Adults
Sponsor:
Sabine Mueller, MD, PhD
Location:
Code:
NCT04323046
Conditions
Glioblastoma
Malignant Glioma
Recurrent Glioblastoma
Recurrent Malignant Glioma
Recurrent Grade III Glioma
Eligibility Criteria
Sex: All
Age: 6 - 25
Healthy Volunteers: Not accepted
Interventions
Nivolumab
Quality-of-Life Assessment
Questionnaire Administration
AspirinUsing Aspirin to Improve Immunological Features of Ovarian Tumors
Sponsor:
H. Lee Moffitt Cancer Center and Research Institute
Location:
Code:
NCT05080946
Conditions
Ovarian Cancer
Fallopian Tube Cancer
Peritoneal Cancer
Eligibility Criteria
Sex: Female
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Aspirin 325mg
Placebo
TebapivatA Study of Tebapivat (AG-946) in Participants With Anemia Due to Lower-Risk Myelodysplastic Syndromes (LR-MDS)
Sponsor:
Agios Pharmaceuticals, Inc.
Location:
Code:
NCT05490446
Conditions
Myelodysplastic Syndromes
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Tebapivat
SBRTSBRT of Metastases Following Neo-adjuvant Treatment for Colorectal Cancer With Synchronous Liver Metastases
Sponsor:
AHS Cancer Control Alberta
Location:
Code:
NCT05775146
Conditions
Colorectal Cancer
Liver Metastasis Colon Cancer
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
stereotactic body radiation treatment (SBRT)
Palliadelic TreatmentPalliadelic Treatment to Reduce Psychological Distress in Persons With Advanced Gastrointestinal Cancers
Sponsor:
University of Nebraska
Location:
Code:
NCT05220046
Conditions
Pancreas Cancer
Biliary Tract Cancer
Psychological Distress
Gastrointestinal Cancer
Eligibility Criteria
Sex: All
Age: 19 - 70+
Healthy Volunteers: Not accepted
Interventions
Psilocybin
EGFR806 CAR T CellEGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults
Sponsor:
Seattle Children's Hospital
Location:
Code:
NCT03618381
Conditions
Pediatric Solid Tumor
Germ Cell Tumor
Retinoblastoma
Hepatoblastoma
Wilms Tumor
Eligibility Criteria
Sex: All
Age: 1 - 30
Healthy Volunteers: Not accepted
Interventions
second generation 4-1BBζ EGFR806-EGFRt
second generation 4-1BBζ EGFR806-EGFRt and a second generation 4 1BBζ CD19-Her2tG
RISEVirtual Home-based Exercise Intervention (RISE) to Improve Cancer-Related Cognitive Impairment and Gut Microbiome in Adolescent and Young Adult Brain Tumor Survivors
Sponsor:
Emory University
Location:
Code:
NCT06799481
Conditions
Cancer-related Cognitive Dysfunction
Primary Brain Neoplasm
Eligibility Criteria
Sex: All
Age: 15 - 39
Healthy Volunteers: Not accepted
Interventions
Aerobic Exercise
Behavioral Intervention
Follow-Up
Internet-Based Intervention
Medical Device Usage and Evaluation
What are clinical trials for cancer?
Clinical trials for cancer are research studies that aim to evaluate new ways to prevent, detect, or treat cancer. These trials test the safety and effectiveness of new treatments, procedures, or drugs in comparison to current standards. They may also show which medical approaches work best for certain types of cancer or groups of people.
The importance of clinical trials in cancer research
Cancer clinical trials are crucial for developing new methods to fight cancer, improving patient outcomes, and may offer participants access to cutting-edge therapies before they are widely available.
Types of cancer clinical trials
Oncology clinical trials are designed to address different aspects of cancer care, including how to treat cancer, prevent it, find it early, or improve the quality of life for people with cancer. The main types are:
Treatment trials
Treatment trials test new treatments or new combinations of treatments, such as new drugs, new surgical techniques, or new radiation therapies. The goal is to find more effective ways to treat cancer with fewer side effects.
Prevention trials
Prevention trials look for better ways to prevent cancer in people who have never had cancer or to prevent cancer from returning. These trials may include studying medicines, vaccines, vitamins, minerals, or lifestyle changes.
Screening trials
Screening trials test the best way to detect cancer, especially in its early stages. These trials study new examinations or tests that might be more effective, safer, or less invasive than the current standard screening methods.
Quality of life trials for cancer survivors
Quality of life trials (or supportive care trials) explore ways to improve comfort and the quality of life for individuals with terminal types of cancer and cancer survivors. They may study issues such as managing side effects of treatment, physical, psychological, and social side effects of cancer and its treatment.
Who can participate in oncology trials?
Eligibility for oncology trials varies widely depending on the study's objectives. Factors can include the type and stage of cancer, previous treatment history, age, gender, overall health, and other medical conditions. Researchers conducting the trial set specific criteria for each trial to ensure accurate and reliable results and to keep participants safe.
What to expect when participating in a cancer clinical trial
Participating in a cancer clinical trial often involves detailed screenings, regular health check-ups, and a structured treatment plan. Participants may receive the new treatment being tested, a standard treatment for their cancer, or a placebo, depending on the trial's design. Throughout the trial, researchers will monitor the health of participants and the effectiveness and side effects of the treatment.
Benefits and risks of participating in cancer clinical trials
Participating in cancer clinical trials offers potential benefits, including access to new treatments before they are widely available and contributing to medical research that may benefit others in the future. They also receive close monitoring from a dedicated healthcare team.
However, there are also risks, such as the new treatments under study are not always better than the standard care, and there may be unexpected side effects. Participation may also require more of their time and attention, including trips to the study site, more treatments, hospital stays, or complex dosage requirements.
Unsure about participating in clinical trials? Dive into our comprehensive guide to learn about the process, benefits, and potential impact of your involvement. Get the facts you need to make an informed decision today!
How to enroll in a clinical trial for cancer
Enrolling in a cancer clinical trial through our platform is a straightforward and user-friendly process. Here's how to get started:
- Identify Your Trial: Use our intuitive search bar or filter options to locate clinical trials specific to your cancer type. This first step simplifies the process of finding relevant research studies tailored to your needs.
- Select Your Preferred Location: To find trials conveniently located near you, simply input your preferred location into the dedicated filter bar on the left-hand side of the page.
- Explore Study Details: For in-depth information about each study, simply click the “Learn More” button. This will provide you with comprehensive details about the trial, including objectives, procedures, and eligibility criteria.
- Complete the Health Profile: After clicking on the “Get started” button you will be taken to our efficient 5-step application process to provide important health information. This helps us match you with the clinical trial that best fits your needs.
- Submit the Application: After completing the application, send it in. A clinical trial coordinator will review it and contact you regarding the possibility of participation.