Find clinical trials for stem cells. Search for stem cells clinical trials in different cities and states across the United States.
Sponsor:
CHU de Quebec-Universite Laval
Location:
Code:
NCT01756365
Conditions
Limbal Stem Cell Deficiency
Eligibility Criteria
Sex: All
Age: 1+
Healthy Volunteers: Not accepted
Interventions
Surgical transplantation of ACCE
Sponsor:
University of Leicester
Location:
Code:
NCT00020566
Conditions
Sarcoma
Eligibility Criteria
Sex: All
Age: 0 - 49
Healthy Volunteers: Not accepted
Interventions
dactinomycin
busulfan
doxorubicin hydrochloride
etoposide
ifosfamide
Sponsor:
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Location:
Code:
NCT06398457
Conditions
Hematologic Malignancy
Bone Marrow Transplant Rejection
Acute Myeloid Leukemia (AML)
Myelodysplastic Syndromes (MDS)
Acute Lymphoblastic Leukemia (ALL), Adult
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Darzalex Faspro (Daratumumab and hyaluronidase-fihj)
JH-DSA Semi-Quant Screen and Response Score
Sponsor:
Henry Ford Health System
Location:
Code:
NCT03850366
Conditions
Hematological Malignancy
Eligibility Criteria
Sex: All
Age: 18 - 65
Healthy Volunteers: Not accepted
Interventions
Bortezomib
Sponsor:
Mitchell Cairo
Location:
Code:
NCT04099966
Conditions
Acute Leukemia
Severe Aplastic Anemia
Non-hodgkin Lymphoma
Hodgkin Lymphoma
Kostmann
Eligibility Criteria
Sex: All
Age: 1 - 30
Healthy Volunteers: Not accepted
Interventions
alpha beta depletion
Sponsor:
M.D. Anderson Cancer Center
Location:
Code:
NCT04565665
Conditions
COVID-19 Infection
COVID-19-Associated Acute Respiratory Distress Syndrome
Hematopoietic and Lymphoid Cell Neoplasm
Malignant Solid Neoplasm
Symptomatic COVID-19 Infection Laboratory-Confirmed
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Best Practice
Mesenchymal Stem Cell
Sponsor:
Andrews Research & Education Foundation
Location:
Code:
NCT05582226
Conditions
ACL Tear
Eligibility Criteria
Sex: All
Age: 14 - 50
Healthy Volunteers: Not accepted
Interventions
ACL reconstruction
Mesenchymal stem cell implantation
Stem cell clinical trials are research studies that explore the therapeutic potential of stem cells for treating a wide range of diseases and conditions. These trials investigate various types of stem cells, including embryonic stem cells, induced pluripotent stem cells (iPSCs), mesenchymal stem cells (MSCs), hematopoietic stem cells (HSCs), and adipose-derived stem cells. These trials aim to develop treatments for a wide range of conditions, such as cardiovascular diseases, neurological disorders, autoimmune diseases, orthopedic injuries, Alzheimer's disease, Crohn's disease and cancer.
Clinical trials for stem cells are crucial for advancing regenerative medicine and offering hope for patients with conditions that are currently difficult to treat. These studies help to determine the safety, efficacy, and optimal use of stem cell therapies, potentially leading to breakthroughs in the treatment of chronic diseases, immune disorders, and injuries. They play a vital role in understanding how stem cells can be used to repair damaged tissues, treat malignancies, and improve patient outcomes.
Stem cell clinical trials investigate a variety of interventions aimed at utilizing the unique properties of stem cells for therapeutic purposes. Some common types of interventions studied in stem cell clinical trials include:
These trials assess the use of stem cells derived from both the patient (autologous) and donors (allogeneic) for the treatment of hematologic diseases, solid tumors, and immune disorders, aiming to restore normal cell function and immune response.
Some trials focus on using stem cells to replace or repair damaged or dysfunctional cells or tissues in the body. For example, mesenchymal stem cells (MSCs) may be used to regenerate bone, cartilage, or muscle tissue in orthopedic conditions, while hematopoietic stem cell transplants are used to replace damaged blood-forming cells in conditions such as leukemia or aplastic anemia.
Clinical trials are investigating stem cells for their potential to stimulate tissue regeneration and repair. This includes approaches such as seeding stem cells onto scaffolds or matrices to create tissue-engineered constructs for transplantation. Research includes developing bioengineered tissues and organs using stem cells to replace damaged tissues in conditions like Crohn's disease-related fistulas, cartilage defects, and chronic pancreatitis.
Gene-modified stem cell therapies are being investigated for their potential in treating genetic disorders, metabolic diseases, and certain types of cancer. For example, genetically modified hematopoietic stem cells may be used to treat inherited blood disorders like sickle cell disease or beta-thalassemia.
Clinical trials are studying stem cell therapies for their potential to protect and regenerate neurons in neurodegenerative diseases and neurological injuries. This includes approaches such as transplantation of neural stem cells or mesenchymal stem cells, as well as promoting endogenous neurogenesis and synaptic repair.
Eligibility for stem cells clinical trials varies widely, targeting specific diseases, age groups, and health conditions. Trials may be open to individuals with specific diagnoses, such as leukemia, Alzheimer's disease, or organ-specific injuries. Criteria often include the stage of the disease, previous treatments, and overall health status.
Participants can expect thorough screening for eligibility, comprehensive information about the study's purpose and procedures, and close monitoring throughout the trial. This may involve receiving stem cell infusions, undergoing surgical procedures for tissue transplantation, and participating in follow-up assessments to monitor the therapy's effectiveness and any side effects.
Worried about the risks of participating in a clinical trial? Delve into our comprehensive guide to gain insights into the potential outcomes of participating. Learn about potential risks, benefits, and safety considerations to make an informed decision about your participation in a clinical trial.
Enrolling in a stem cell clinical trial through our platform is a straightforward and user-friendly process. Here's how to get started: