Dystrophy Clinical Trials

Find clinical trials for Dystrophy. Search for Dystrophy clinical trials in different cities and states across the United States.

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Results: 333

A Gene Transfer Therapy to Evaluate the Safety and Efficacy of Delandistrogene Moxeparvovec (SRP-9001) Following Therapeutic Plasma Exchange (Plasmapheresis) in Participants With Duchenne Muscular Dystrophy (DMD) and Pre-existing Antibodies to AAVrh74A Gene Transfer Therapy to Evaluate the Safety and Efficacy of Delandistrogene Moxeparvovec (SRP-9001) Following Therapeutic Plasma Exchange (Plasmapheresis) in Participants With Duchenne Muscular Dystrophy (DMD) and Pre-existing Antibodies to AAVrh74

Recruiting

PHASE1

Sponsor:

Sarepta Therapeutics, Inc.

Location:

Saint Louis MO, Columbus OH

Code:

NCT06597656

Conditions

Duchenne Muscular Dystrophy

Eligibility Criteria

Sex: Male

Age: 4 - 8

Healthy Volunteers: Not accepted

Interventions

delandistrogene moxeparvovec

Plasmapheresis

Observational StudyClinical Trial Readiness to Solve Barriers to Drug Development in FSHD

Recruiting

Sponsor:

University of Kansas Medical Center

Location:

Los Angeles CA, Kansas City KS, Baltimore MD, Rochester NYshow 4 more

Code:

NCT03458832

Conditions

Facioscapulohumeral Muscular Dystrophy

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

FSHD-specific functional rating scale

Electrical Impedance Myography

GlanatecGlanatec(R) for Descemet Stripping in Fuch's Endothelial Dystrophy

Recruiting

Sponsor:

Marian Macsai, MD

Location:

Glenview IL

Code:

NCT03249337

Conditions

Fuchs' Endothelial Dystrophy

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Ripasudil hydrochloride hydrate 0.4% ophthalmic solution

Observational StudyAdaptive Optics Imaging of Outer Retinal Diseases

Recruiting

Sponsor:

Food and Drug Administration (FDA)

Location:

Bethesda MD, Silver Spring MD

Code:

NCT05355415

Conditions

Retinal Degeneration

Age-Related Macular Degeneration

Retinitis Pigmentosa

Hydroxychloroquine Retinopathy

Usher Syndromes

Eligibility Criteria

Sex: All

Age: 21+

Healthy Volunteers: Not accepted

Interventions

Adaptive optics imaging

Endoglide vs. EndoserterComparing Endoglide to Endoserter for DSAEK Graft Insertion

Recruiting

Sponsor:

University Health Network, Toronto

Location:

Toronto

Code:

NCT01791075

Conditions

Fuch's Endothelial Dystrophy

Bullous Keratopathy, Unspecified Eye

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Tan Endoglide

Endosaver

Observational StudyWearable Technology to Evaluate Hyperglycemia and HRV in DMD - Longitudinal Aim

Recruiting

Sponsor:

Vanderbilt University Medical Center

Location:

Nashville TN

Code:

NCT06093100

Conditions

Duchenne Muscular Dystrophy

Eligibility Criteria

Sex: Male

Age: 10+

Healthy Volunteers: Not accepted

Interventions

wearable technology

RGX-202AFFINITY DUCHENNE: RGX-202 Gene Therapy in Participants with Duchenne Muscular Dystrophy (DMD)

Recruiting

PHASE2

PHASE3

Sponsor:

REGENXBIO Inc.

Location:

Little Rock AR, Palo Alto CA, Aurora CO, Chicago ILshow 2 more

Code:

NCT05693142

Conditions

Duchenne Muscular Dystrophy

Eligibility Criteria

Sex: Male

Age: 1+

Healthy Volunteers: Not accepted

Interventions

RGX-202

OCTOCT in Diagnosis of Irregular Corneas

Recruiting

Sponsor:

Oregon Health and Science University

Location:

Portland OR

Code:

NCT03504800

Conditions

Keratoconus

Corneal Opacity

Corneal Dystrophy

Eligibility Criteria

Sex: All

Age: 14 - 70+

Healthy Volunteers: Accepted

Interventions

Optical Coherence Tomography

AB-1003A Study to Evaluate the Safety of AB-1003 (Previously LION-101) in Subjects With Genetic Confirmation of LGMD2I/R9 (Part1)

Recruiting

PHASE1

PHASE2

Sponsor:

AskBio Inc

Location:

Irvine CA, Iowa City IA, Kansas City KS, Baltimore MDshow 2 more

Code:

NCT05230459

Conditions

Limb Girdle Muscular Dystrophy

Limb-Girdle Muscular Dystrophy Type 2

LGMD2I

Muscular Dystrophy

LGMD2

Eligibility Criteria

Sex: All

Age: 18 - 65

Healthy Volunteers: Not accepted

Interventions

AB-1003 dose level 1

AB-1003 dose level 2

Placebo

Observational StudyEstab Biomarkers and Clinical Endpoints in Myotonic Dystrophy Type 1 (END-DM1)

Recruiting

Sponsor:

Virginia Commonwealth University

Location:

Quebec, La Jolla CA, Los Angeles CA, Stanford CAshow 8 more

Code:

NCT03981575

Conditions

Myotonic Dystrophy 1

DM1

Eligibility Criteria

Sex: All

Age: 18 - 70

Healthy Volunteers: Not accepted