Find clinical trials for Endometriosis. Search for Endometriosis clinical trials in different cities and states across the United States.
Sponsor:
AbbVie
Location:
Code:
NCT04333576
Conditions
Endometriosis
Eligibility Criteria
Sex: Female
Age: 18 - 49
Healthy Volunteers: Not accepted
Interventions
Elagolix
Placebo
Combined Oral Contraceptive
Sponsor:
Milton S. Hershey Medical Center
Location:
Code:
NCT06141720
Conditions
Endometriosis
Pain
Mindfulness
Eligibility Criteria
Sex: Female
Age: 18+
Healthy Volunteers: Not accepted
Interventions
pain education
mindfulness of pain introduction and intervention
Sponsor:
University of Illinois at Urbana-Champaign
Location:
Code:
NCT03784976
Conditions
Secondary Dysmenorrhea
Dysmenorrhea
Dysmenorrhea Secondary
Polycystic Ovary Syndrome
Endometriosis
Eligibility Criteria
Sex: Female
Age: 12 - 65
Healthy Volunteers: Not accepted
Interventions
Iyengar Yoga Therapy
Sponsor:
UCLA
Location:
Code:
NCT03991520
Conditions
Endometriosis
Anakinra
Markers of Inflammation
Eligibility Criteria
Sex: Female
Age: 18 - 45
Healthy Volunteers: Not accepted
Interventions
Anakinra 100Mg/0.67Ml Inj Syringe
Placebo
Sponsor:
Enteris BioPharma Inc.
Location:
Code:
NCT05096065
Conditions
Endometriosis
Eligibility Criteria
Sex: Female
Age: 18 - 49
Healthy Volunteers: Not accepted
Interventions
Leuprolide Oral Tablet - 120 mg - QD- Treatment A
Leuprolide Oral Tablet - 80 mg - QD - Treatment B
Leuprolide Oral Tablet - 60 mg - QD - Treatment C
Leuprolide Oral Tablet - 60 mg - BID - Treatment D
Leuprolide Oral Tablet - 40 mg - BID - Treatment E
Sponsor:
Sumitomo Pharma Switzerland GmbH
Location:
Code:
NCT05862272
Conditions
Uterine Fibroids
Endometriosis
Eligibility Criteria
Sex: Female
Age: 18 - 50
Healthy Volunteers: Not accepted
Interventions
Relugolix Combination Tablet
Sponsor:
Organon and Co
Location:
Code:
NCT05560646
Conditions
Endometriosis
Eligibility Criteria
Sex: Female
Age: 18 - 49
Healthy Volunteers: Not accepted
Interventions
OG-6219
Placebo
Sponsor:
Penn State University
Location:
Code:
NCT05059626
Conditions
Endometriosis
Eligibility Criteria
Sex: Female
Age: 18 - 45
Healthy Volunteers: Not accepted
Interventions
simvastatin 10mg
Bazedoxifene 20/Estrogens,Con 0.45Mg Tb
Sponsor:
Hope Medicine (Nanjing) Co., Ltd
Location:
Code:
NCT05101317
Conditions
Endometriosis
Eligibility Criteria
Sex: Female
Age: 18 - 49
Healthy Volunteers: Not accepted
Interventions
HMI-115
Placebo
In clinical trials for endometriosis, researchers seek to investigate new treatments, improve existing therapies, and advance the understanding of this chronic condition. Endometriosis occurs when tissue similar to the lining of the uterus grows outside the uterus, causing pain and potential infertility. Clinical trials explore various aspects of managing and treating endometriosis to improve outcomes for patients and potentially establish a cure or preventative treatment.
Endometriosis clinical trials are crucial for advancing the understanding and treatment of this complex and often debilitating condition. These trials play a key role in evaluating new therapies, improving existing treatments, and exploring innovative diagnostic methods. By testing novel medications, surgical techniques, and lifestyle interventions, endometriosis clinical trials aim to enhance symptom management, reduce pain, and improve the overall quality of life for those affected.
Clinical trials for endometriosis can also help to uncover the underlying mechanisms of the disease, which can lead to more targeted and effective treatments in the future. This ongoing research is essential for finding better solutions, as current treatments may not be effective for everyone and often come with significant side effects.
Researchers use several types of clinical trials to investigate and manage endometriosis. Each type focuses on different aspects of the condition, including treatment, diagnosis, and understanding disease mechanisms.
The purpose of genetic and biomarker studies in endometriosis is to explore the underlying biological factors that may predispose individuals to develop the condition, determine the severity of the disease, or predict responses to specific treatments. These studies focus on identifying genetic variations, such as specific gene mutations or polymorphisms, that may increase the risk of endometriosis, thereby helping to uncover the hereditary aspects of the disease.
Researchers aim to discover biomarkers - measurable indicators such as proteins, hormones, or molecular signatures present in blood, tissue, or other bodily fluids - that could serve as early warning signs of endometriosis or provide insights into its progression. By pinpointing these genetic markers and biomarkers, these studies seek to improve diagnostic accuracy, enable earlier detection, and pave the way for personalized treatment approaches tailored to an individual’s unique genetic and molecular profile.
Diagnostic trials in endometriosis clinical research focus on improving and validating methods for diagnosing the condition. These trials aim to enhance the accuracy, speed, and effectiveness of diagnosing endometriosis, which can often be challenging due to its complex and variable symptoms.
Researchers might seek to develop and refine diagnostics tools and methods for enhancing the accuracy and early detection of endometriosis. This could include placing a focus on advanced imaging technologies like high-resolution ultrasound or MRI or identifying new biomarkers that could support earlier and more reliable diagnosis.
Researchers use interventional trials for endometriosis to test and evaluate the effectiveness and safety of new or modified treatments and therapies. These trials are designed to directly intervene in the disease process or its symptoms and assess the impact of these interventions.
In interventional trials, researchers will seek to establish how safe and effective an intervention is. Medications could include novel hormone therapies, pain management medications, or other pharmacological agents. As surgery is an existing treatment for endometriosis, researchers can also use interventional trials to investigate new or improved surgical methods such as techniques for removing endometrial tissue. Non-pharmacological interventions may also be tested, such as lifestyle changes, dietary modifications, or complementary therapies.
Prevention trials in endometriosis are designed to identify and evaluate strategies that can prevent the initial development of the disease or its recurrence following treatment. Given the chronic nature of endometriosis, these trials are crucial for reducing the incidence and recurrence of the condition, which in turn can lessen the physical, emotional, and financial burdens on patients.
Observational studies for endometriosis can be used to gather data on the disease's natural history, identify risk factors, and understand how various factors affect disease progression and treatment outcomes. Unlike interventional studies, observational studies do not involve manipulating variables or testing specific interventions. Instead, they observe and analyze existing conditions and patterns.
Researchers may track how endometriosis develops and progresses over time in individuals without intervening to help them understand the typical course of the disease and its variations among different patients. In this case, they would collect longitudinal data from patients over several years to document changes in symptoms, disease severity, and overall health.
Deciding to take part in an endometriosis clinical trial is a big decision, with several factors to consider before signing up. However, it can also be hugely beneficial for both participants and the wider medical research landscape.
Considering volunteering in a clinical trial? Explore our comprehensive guide to learn more about why people choose to volunteer and the impact you can make in advancing medical research. Discover the process of volunteering, what to consider before applying and the potential benefits and risks involved.
Participating in an endometriosis clinical trial offers several benefits, including access to cutting-edge treatments and diagnostic methods. Participants might receive close monitoring and specialized care from experts, which can lead to improved symptom management and overall health.
Involvement in endometriosis clinical trials also contributes valuable data that advances medical knowledge, enhances treatment options, and potentially benefits others with the condition. By participating, individuals play a crucial role in shaping the future of endometriosis care and improving outcomes for themselves and others affected by the condition.
The main risk of participating in a clinical trial for endometriosis is that participants may experience unknown side effects or adverse reactions from experimental treatments, as these interventions are still under evaluation. The trials can also require a significant time commitment, including frequent visits, tests, and procedures, which may be demanding. There is also no guarantee that the new treatment will be effective or better than existing options.
There are several factors that could determine a person’s eligibility for participation in an endometriosis clinical trial. The eligibility criteria will be set out by the research team and could include factors such as endometriosis diagnosis stage, age, severity and stage of disease, health status, reproductive status, and previous treatments.
The strict criteria laid out by the research team are designed to ensure the safety of participants and the validity of trial results. Potential participants should ensure they consult with healthcare providers and review the specific criteria for each trial to determine suitability.
Any clinical trial will involve a robust process, which begins with screening and assessment to
determine if you meet the trial's eligibility criteria. Once informed consent has been provided, and if you’re suitable, you'll start to receive either the experimental treatment or a placebo, depending on the trial's design.
Regular follow-up visits could be required to monitor your response to the treatment, including assessments of symptom changes, side effects, and overall health. You will also most likely need to provide feedback on your experience, and receive specialized care and support from healthcare professionals.
It’s important for individuals to carefully review the informed consent documents, discuss potential risks and benefits with their healthcare team, and consider how participation aligns with their personal health needs and lifestyle.
Enrolling in a clinical trial studying endometriosis through our platform is a straightforward and user-friendly process. Here's how to get started: