Find clinical trials for Herpes. Search for Herpes clinical trials in different cities and states across the United States.
Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Location:
Code:
NCT05468619
Conditions
Herpes Simplex
Eligibility Criteria
Sex: All
Age: 1 - 2
Healthy Volunteers: Not accepted
Interventions
Valacyclovir
Sponsor:
AiCuris Anti-infective Cures AG
Location:
Code:
NCT03073967
Conditions
HSV Infection
Eligibility Criteria
Sex: All
Age: 16+
Healthy Volunteers: Not accepted
Interventions
Pritelivir
Investigator's choice
Sponsor:
National Center for Research Resources (NCRR)
Location:
Code:
NCT00006132
Conditions
Herpes Simplex
Eligibility Criteria
Sex: All
Age: 0 - 28
Healthy Volunteers: Not accepted
Interventions
acyclovir
Herpes clinical trials are medical research studies designed to investigate new treatments, improve existing therapies, and enhance the understanding of herpes simplex virus (HSV) infections. Herpes is a common viral infection caused by HSV, which can lead to oral herpes (cold sores) and genital herpes. Most clinical trials for herpes focus on various aspects of managing and treating the virus.
There are many reasons why clinical trials for herpes are important. As such a common virus, affecting between 50 and 80% of Americans, researchers are keen to continue developing new treatments and preventative measures to quell the prevalence of it.
Herpes clinical trials help identify and evaluate new treatments that can more effectively manage herpes simplex virus (HSV) infections, which include both oral and genital herpes. Current treatments primarily focus on managing symptoms and reducing outbreaks, but clinical trials aim to discover more potent antiviral drugs, vaccines, and other therapies that could offer better control or even a cure for the infection.
These trials contribute to a deeper understanding of the virus and its interactions with the immune system. This knowledge can lead to improved strategies for preventing transmission and reducing the frequency of outbreaks. Vaccine trials, for instance, are particularly important as they seek to prevent HSV infections altogether or mitigate their severity.
Depending on the objective of the trial, researchers may use one or more different methods of clinical trial design to gather the necessary data. Each type has advantages for researchers, with the method chosen largely depending on the desired outcome.
Researchers use interventional trials for herpes to directly test and evaluate new or existing treatments and therapeutic approaches to better manage the infection. These trials involve administering experimental drugs, topical treatments, immunotherapy treatments, or other interventions to participants to assess their efficacy in reducing symptoms, preventing outbreaks, or curing the infection.
By comparing the outcomes of the new interventions against standard treatments or placebos, researchers can determine their effectiveness, safety, and potential side effects. This approach helps advance treatment options, improve patient care, and contribute to a better understanding of herpes management.
Vaccine trials for herpes are used to develop and evaluate vaccines that could prevent herpes simplex virus (HSV) infections or reduce the severity and frequency of outbreaks. In these trials, participants receive either the experimental vaccine or a placebo, and their immune responses to the vaccine are monitored.
Researchers assess the vaccine's effectiveness in preventing new infections or managing existing ones, while also evaluating its safety and potential side effects. By testing these vaccines, researchers aim to provide a preventive measure that could significantly reduce the incidence and impact of herpes, ultimately improving public health outcomes.
Interested in learning more about the duration and phases of vaccine clinical trials? Read all about the timelines, stages, and factors influencing the length of these trials in our guide.
Herpes diagnosis is also an important consideration in medical research. Diagnostic trials can evaluate and improve methods for detecting herpes simplex virus (HSV) infections more accurately and efficiently. These trials involve testing new diagnostic tools or techniques, such as advanced molecular assays or rapid tests, and comparing their performance against existing methods.
Assessing the accuracy, sensitivity, and specificity of these new diagnostic approaches means researchers can enhance early detection and diagnosis of herpes, supporting better management of the virus.
Participating in a clinical trial for herpes is a big decision, which can offer significant benefits as well as risks and considerations. There are multiple reasons why taking part is a good idea, for both participants and the wider community.
The key benefit of deciding to take part in a herpes clinical trial can mean that you gain access to innovative treatments and diagnostic methods that are not yet widely available. Additionally, participants may receive close monitoring and specialized care from medical professionals, which can lead to improved management of symptoms and better overall health.
Being part of a clinical trial for herpes contributes to advancing scientific knowledge and the development of new therapies, potentially benefiting others affected by herpes in the future. By participating, individuals play a key role in enhancing treatment options and improving quality of life for the wider community.
Side effects are the main risk factors for participating in a herpes clinical trial, or any type of clinical trial. In experimental treatment trials, potential side effects may be unknown or not yet understood which can be unsettling for some participants. Herpes clinical trials may also require frequent visits, additional tests, or procedures, which can be time-consuming and demanding.
Participants must weigh these risks against the potential benefits, such as access to cutting-edge therapies and contributing to valuable research that may improve future herpes management. It’s crucial to discuss these factors with healthcare providers and thoroughly review the informed consent documents before participating.
Eligibility for a herpes clinical trial typically depends on specific criteria outlined by the research team involved in designing the study. Generally, individuals must have a confirmed diagnosis of herpes simplex virus (HSV) infection, whether oral or genital, and meet other requirements set by the trial. Other requirements could include age, gender, overall health status, and previous treatment choices.
Some trials may focus on participants with specific stages of the disease, while others might include those who have not responded well to standard treatments. Overall health is also considered, with trials usually excluding individuals with significant other health conditions that could affect study outcomes.
There are several key steps involved in the process of a herpes clinical trial, typically starting with thorough screening and assessment to ensure you are eligible to take part. If enrolled, you will start undergoing treatment and will be closely monitored through regular visits and assessments. This may include tests to evaluate the effectiveness of the intervention, as well as tracking any side effects or changes in symptoms.
Throughout the trial, you'll have the opportunity to provide feedback on your experience, with support from medical professionals.
Enrolling in a clinical trial studying herpes through our platform is a straightforward and user-friendly process. Here's how to get started: