Browse 156 HPV clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.
HPV is so common that most sexually active people get it at some point, and the body usually clears it without anyone knowing. When it lingers, certain types can cause cancer years later, including more than 90 percent of cervical cancers and most cancers of the throat. A vaccine that prevents these infections has been available since 2006. The vaccine does not treat an infection that is already there, and trials are testing therapeutic vaccines and treatments that clear HPV and precancer before it becomes cancer.
The Natural History of Severe Viral Infections and Characterization of Immune Defects in Patients Without Known Immunocompromise
for
EBV, HSV, VZV, HPV, CMV
Location: Bethesda MD
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Sex: All
Age: 2 - 70+
Code: NCT01011712
Recruiting
Active & Responsive
Comparative Self-collection for Cervical Cancer Screening Pivotal Study
for
HPV, HPV - Anogenital Human Papilloma Virus Infection
Location: Wilmington NC, Raleigh NC, Lake Worth FL,
Sponsor: Mel Mont Medical
Sex: Female
Age: 25 - 65
Code: NCT07758140
Recruiting
Active & Responsive
TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer
for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Atlanta GA
Sponsor: Emory University
Sex: All
Age: 18+
Code: NCT06868433
Phase 1, Recruiting
Active & Responsive
BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study
for
Clinical Stage III Cutaneous Melanoma AJCC v8,
Location: Springfield MA, Saint Johnsbury VT, Lebanon NH,
Sponsor: National Cancer Institute (NCI)
Sex: All
Age: 18+
Code: NCT05136196
Phase 2, Recruiting
Active & Responsive
HPV DNA Vaccine Via Electroporation for HPV16 Positive Cervical Neoplasia
for
Human Papillomavirus Type 16,
Location: Baltimore MD, Birmingham AL
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Sex: Female
Age: 19+
Code: NCT04131413
Phase 1, Recruiting
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Active & Responsive
Prospective Assessment of HPV Associated Anogenital Pathology in Female Patients and Female Partners of Patients With Confirmed HPV Associated Oropharyngeal Carcinoma, PAP-OP Study
for
Oropharyngeal Human Papillomavirus-Positive Squamous Cell Carcinoma,
Location: Rochester MN
Sponsor: Mayo Clinic
Sex: Female
Age: 18+
Code: NCT06115772
Recruiting
Active & Responsive
A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors
for
Advanced Solid Tumors, Genital Neoplasm, Female,
Location: Boston MA, Bethesda MD, Toronto, Celebration FL,
Sponsor: Marengo Therapeutics, Inc.
Sex: All
Age: 18+
Code: NCT05592626
Phase 1, Phase 2, Recruiting
Active & Responsive
Screening Women With Prior HPV for Anal Neoplasia
for
HPV-related Lower Genital Tract Neoplasias,
Location: New York NY, Charleston SC, Houston TX
Sponsor: Icahn School of Medicine at Mount Sinai
Sex: Female
Age: 35+
Code: NCT05217940
Recruiting
Active & Responsive
Comparing Immune Response of 2 vs 3 HPV Doses (27-45 Years Old)
for
Immunization, HPV Infection, Human Papillomavirus
Location: Galveston TX
Sponsor: The University of Texas Medical Branch, Galveston
Sex: Female
Age: 27 - 45
Code: NCT05672927
Recruiting
Active & Responsive
Unidos Contra el VPH
for
Human Papilloma Virus (HPV), Cervical Cancers
Location: El Paso TX
Sponsor: University of Texas at Austin
Sex: Female
Age: 30 - 65
Code: NCT06825689
Recruiting
Active & Responsive
Evaluating Gardasil HPV Vaccine Humoral and Cellular Immune Responses in People With and Without HIV
for
Human Papilloma Virus, Anal Dysplasia, HIV
Location: Baltimore MD
Sponsor: University of Maryland, Baltimore
Sex: Male
Age: 18 - 70
Code: NCT06624839
Phase 2, Recruiting
Active & Responsive
Assessing Administration of pBI-11 Via Electroporation for the Treatment of Patients With HPV16/18+
for
HPV Infection
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Sex: Female
Age: 18+
Code: NCT06210854
Phase 2, Recruiting
Active & Responsive
Using Plasma Human Papillomavirus (HPV)-Related Deoxyribonucleic Acid (DNA) and Ribonucleic Acid (RNA) to Follow Response of Cervical Cancer to Surgery, Radiation, and Chemotherapy
for
Cervical Cancer, Human Papilloma Virus (HPV)
Location: Gainesville FL
Sponsor: University of Florida
Sex: Female
Age: 18 - 70+
Code: NCT07214584
Recruiting
Active & Responsive
Neoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head and Neck Cancer Treatment De-escalation (NeoScorch HN)
for
Head and Neck Cancer, Squamous Cell Carcinoma,
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Sex: All
Age: 18+
Code: NCT07209189
Phase 2, Recruiting
Active & Responsive
CASCADE 2002: PROTECT Study, "PRObiotics to TrEat Anal preCancer Trial
for
HSIL, High Grade Squamous Intraepithelial Lesion,
Location: San Francisco CA
Sponsor: University of California, San Francisco
Sex: All
Age: 21+
Code: NCT06949800
Phase 2, Recruiting
Active & Responsive
Comparing Radiation Plus Cetuximab to Radiation Plus Chemotherapy in People With Head and Neck Cancer Who Cannot Receive Cisplatin
for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Stony Brook NY, Wilmington DE, Chadds Ford PA,
Sponsor: NRG Oncology
Sex: All
Age: 18+
Code: NCT07441681
Phase 3, Recruiting
Active & Responsive
Tirbanibulin for Pediatric Warts
for
Warts Hand
Location: New City NY
Sponsor: The Skin Center Dermatology Group
Sex: All
Age: 8 - 18
Code: NCT06791525
Recruiting
Active & Responsive
Project CONTINUITY: Promoting Evidence-Based Cancer Screening Among Underserved Women
for
Cervical Cancer Screening Methods
Location: Gainesville FL
Sponsor: University of Florida
Sex: Female
Age: 25 - 65
Code: NCT05390567
Recruiting
Active & Responsive
Novel, One Stop, Affordable, Point of Care and AI Supported System of Screening, Triage and Treatment Selection for Cervical Cancer in LMICs
for
Cervical Cancer, Screening
Location: Cincinnati OH
Sponsor: International Agency for Research on Cancer
Sex: Female
Age: 25 - 49
Code: NCT06042543
Recruiting
Active & Responsive
Prospective Observational Study to Validate Circulating HPVDNA and Prognostic Genomic Biomarkers in HPV-associated OPSCC