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Leukemia Clinical Trials

Find clinical trials for Leukemia. Search for Leukemia clinical trials in different cities and states across the United States.

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Intensity Modulated Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients With Relapsed Hematologic Cancers Undergoing a Second Donor Stem Cell Transplant

Recruiting
PHASE1

Sponsor:

University of Chicago

Location:

Chicago IL

Code:

NCT02333162

Conditions

Previously Treated Myelodysplastic Syndrome

Recurrent Adult Acute Lymphoblastic Leukemia

Recurrent Adult Acute Myeloid Leukemia

Recurrent Hematologic Malignancy

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Fludarabine Phosphate

Melphalan

Intensity-Modulated Radiation Therapy

Total Marrow Irradiation

Allogeneic Hematopoietic Stem Cell Transplantation

Anti-CD19 Chimeric Antigen Receptor T Cells for Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma

Recruiting
PHASE1

Sponsor:

C. Babis Andreadis

Location:

San Francisco CA

Code:

NCT04545762

Conditions

Refractory Non-Hodgkin Lymphoma

Burkitt Lymphoma

Mantle Cell Lymphoma

Follicular Lymphoma

Lymphoplasmacytic Lymphoma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Fludarabine

Cyclophosphamide

anti-CD19 CAR-T cells

Venetoclax Combined with Vyxeos (CPX-351) for Participants with Relapsed or Refractory Acute Leukemia

Recruiting
PHASE1

Sponsor:

Children's Hospital Medical Center, Cincinnati

Location:

Cincinnati OH

Code:

NCT03826992

Conditions

Leukemia

Eligibility Criteria

Sex: All

Age: 1 - 39

Healthy Volunteers: Not accepted

Interventions

Vyxeos

Venetoclax

Study of CPX-351 (VYXEOS) in Individuals < 22 Years With Secondary Myeloid Neoplasms

Recruiting
PHASE2

Sponsor:

St. Jude Children's Research Hospital

Location:

Memphis TN

Code:

NCT05656248

Conditions

Myeloid Neoplasm

Eligibility Criteria

Sex: All

Age: 1 - 21

Healthy Volunteers: Not accepted

Interventions

CPX-351

MHA

Allogeneic Hematopoietic Stem Cell Transplantation

Inotuzumab Ozogamicin and Combination Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia

Recruiting
PHASE1
PHASE2

Sponsor:

M.D. Anderson Cancer Center

Location:

Houston TX

Code:

NCT01371630

Conditions

B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1

B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative

Burkitt-Like Lymphoma With 11q Aberration

High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements

High Grade B-Cell Lymphoma, Not Otherwise Specified

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Blinatumomab

Cyclophosphamide

Cytarabine

Dexamethasone

Inotuzumab Ozogamicin

CalPeg for Newly Diagnosed Acute Lymphoblastic Leukemia (ALL)

Recruiting
PHASE1

Sponsor:

H. Lee Moffitt Cancer Center and Research Institute

Location:

Tampa FL

Code:

NCT05581030

Conditions

Acute Lymphoblastic Leukemia

Eligibility Criteria

Sex: All

Age: 18 - 50

Healthy Volunteers: Not accepted

Interventions

Hyper CVAD Protocol (Standard of Care Multi-Agent Chemotherapy)

Calaspargase Pegol

Rituximab

Combination Chemotherapy and Nelarabine in Treating Patients With T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

Recruiting
PHASE2

Sponsor:

M.D. Anderson Cancer Center

Location:

Houston TX

Code:

NCT00501826

Conditions

T Acute Lymphoblastic Leukemia

T Lymphoblastic Lymphoma

Eligibility Criteria

Sex: All

Age: 0 - 70+

Healthy Volunteers: Not accepted

Interventions

Cyclophosphamide

Cytarabine

Dexamethasone

Doxorubicin Hydrochloride

Mercaptopurine

Kappa-CD28 T Lymphocytes, Chronic Lymphocytic Leukemia, B-cell Lymphoma or Multiple Myeloma, CHARKALL

Recruiting
PHASE1

Sponsor:

Baylor College of Medicine

Location:

Houston TX

Code:

NCT00881920

Conditions

Lymphoma

Myeloma

Leukemia

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Kappa CD28 T cells

Pilot Study of Anti-CD19 Chimeric Antigen Receptor T Cells (CAR-T Cells) for the Treatment of Relapsed/Refractory CD19+ Malignancies

Recruiting
PHASE1

Sponsor:

University of Utah

Location:

Salt Lake City UT

Code:

NCT06227026

Conditions

Acute Lymphoblastic Leukemia

Diffuse Large B Cell Lymphoma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Anti-CD19 CAR-T cells

Multi-modality Imaging and Collection of Biospecimen Samples in Understanding Bone Marrow Changes in Patients With Acute Myeloid Leukemia Undergoing TBI and Chemotherapy

Recruiting
EARLY_PHASE1

Sponsor:

City of Hope Medical Center

Location:

Duarte CA

Code:

NCT03422731

Conditions

Acute Lymphoblastic Leukemia

Acute Myeloid Leukemia

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Biospecimen Collection

Dual-Energy Computed Tomography

Fluorothymidine F-18

Laboratory Biomarker Analysis

Magnetic Resonance Imaging

What are clinical trials for leukemia?

Types of clinical trials for leukemia

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How to enroll in a leukemia clinical trial