Browse 232 lupus nephritis clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.
Lupus nephritis is inflammation of the kidneys caused by lupus, and it is one of the most serious complications of the disease because it can lead to kidney failure if not controlled. It often causes no symptoms at first and is found through urine and blood tests, which is why people with lupus are checked regularly. For decades treatment relied on strong immune suppressing drugs, and only in 2020 and 2021 did the first medicines approved specifically for lupus nephritis arrive.
Location: New York NY, Philadelphia PA, Durham NC, Miami FL,
Sponsor: Fate Therapeutics
Sex: All
Age: 12 - 70
Code: NCT06308978
Phase 1, Recruiting
New
Lupus Nephritis Care Pathway
for
Lupus Nephritis (LN)
Location: Durham NC
Sponsor: Duke University
Sex: All
Age: 18+
Code: NCT07783152
Recruiting
The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study
for
Lupus Nephritis
Location: New York NY, Hackensack NJ, Chapel Hill NC,
Sponsor: Children's Hospital Medical Center, Cincinnati
Sex: All
Age: 8 - 20
Code: NCT05538208
Phase 2, Recruiting
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants
for
Lupus Nephritis
Location: Queens NY, Hackensack NJ, Montreal, Toronto, Atlanta GA,
Sponsor: Hoffmann-La Roche
Sex: All
Age: 5 - 17
Code: NCT05039619
Phase 2, Recruiting
A Phase 1/2 Study of NKX019 in Subjects With Autoimmune Disease (Ntrust-1)
for
Lupus Nephritis, Primary Membranous Nephropathy
Location: Worcester MA, New York NY, Summit NJ, Syracuse NY,
Sponsor: Nkarta, Inc.
Sex: All
Age: 18 - 70+
Code: NCT06557265
Phase 1, Phase 2, Recruiting
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Study to Assess Real-world Effectiveness of Belimumab for Treatment of Adults With LN
for
Lupus Nephritis
Location: Baltimore MD, Charlotte NC, Columbus OH, Hixson TN
Sponsor: GlaxoSmithKline
Sex: All
Age: 18+
Code: NCT06527872
Recruiting
VIBRANT: VIB4920 for Active Lupus Nephritis
for
Lupus Nephritis
Location: Manhasset NY, New York NY, Philadelphia PA, Hershey PA,
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Sex: All
Age: 18+
Code: NCT05201469
Phase 2, Recruiting
A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G
for
IgA Nephropathy, Lupus Nephritis (LN),
Location: Hollywood FL, Orangeburg SC, Lawrenceville GA
Sponsor: Akebia Therapeutics
Sex: All
Age: 16+
Code: NCT06419205
Phase 2, Recruiting
Phase III Extension Study of Efficacy and Safety of Ianalumab With or Without Study Treatment Withdrawal in Participants With Lupus Nephritis (SIRIUS-LN Extension)
for
Lupus Nephritis
Location: Orchard Park NY
Sponsor: Novartis Pharmaceuticals
Sex: All
Age: 18 - 70+
Code: NCT06711887
Phase 3, Recruiting
Wellness & Workforce Solution for Lupus/Lupus Nephritis
for
Lupus Nephritis
Location: Atlanta GA
Sponsor: Morehouse School of Medicine
Sex: Female
Age: 18+
Code: NCT06217107
Recruiting
A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101
for
Refractory Lupus Nephritis, Myasthaenia Gravis,
Location: Denver CO
Sponsor: Kyverna Therapeutics
Sex: All
Age: 18+
Code: NCT07403188
Recruiting
Obe-cel in Severe, Refractory Systemic Lupus Erythematosus (SLE) With Active Lupus Nephritis (LN)
for
Lupus Nephritis
Location: New York NY, Syracuse NY, Houston TX, San Antonio TX
Sponsor: Autolus Limited
Sex: All
Age: 12 - 65
Code: NCT07053800
Phase 2, Recruiting
PRESERVE: LUPKYNIS in Combination With Belimumab, Obinutuzumab or Anifrolumab in Patients With Lupus Nephritis
for
Lupus Nephritis
Location: West Long Branch NJ, Willow Grove PA, Rockville MD,
Sponsor: Aurinia Pharmaceuticals Inc.
Sex: All
Age: 18 - 70+
Code: NCT07611214
Recruiting
Dapagliflozin in Active Lupus Nephritis
for
Lupus Nephritis (LN)
Location: Boston MA
Sponsor: Brigham and Women's Hospital
Sex: All
Age: 18 - 70
Code: NCT07323524
Phase 4, Recruiting
Dose Escalation Study With Bispecific Antibodies in Adult Participants With Lupus Nephritis