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Macular Degeneration Clinical Trials

Browse 119 macular degeneration clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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4D-150 in Patients With Neovascular (Wet) Age-Related Macular Degeneration

for
Neovascular (Wet) Age-Related Macular Degeneration
Location: Boston MA, Bethlehem PA, Hagerstown MD,
Sponsor: 4D Molecular Therapeutics

Sex: All

Age: 50+

Code: NCT05197270

Phase1, Phase2, Recruiting

A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy

for
Age-related Macular Degeneration (AMD), Geographic Atrophy (GA)
Location: Boston MA, Waltham MA, Worcester MA, Springfield MA,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 50 - 70+

Code: NCT06541704

Phase3, Recruiting
New

A Study in Adults With Geographic Atrophy

for
Geographic Atrophy
Location: Erie PA, Burleson TX
Sponsor: Sitala Bio LTD

Sex: All

Age: 60+

Code: NCT07606365

Phase2, Recruiting
New

A Phase 1/2 Study of the Safety and Efficacy of BRX011 Oral Administration Once Daily in Subjects With Geographic Atrophy Secondary to Age-Related Macular Degeneration

for
Geographic Atrophy
Location: Beachwood OH, McAllen TX, Abilene TX, Gilbert AZ,
Sponsor: Biojiva LLC

Sex: All

Age: 55+

Code: NCT07029945

Phase1, Phase2, Recruiting

An Observational Study in Subjects to Follow the Progression of Stargardt Disease Type 1 (STGD1) Caused by Bi-Allelic Autosomal Recessive Mutations in the ABCA4 Gene

for
Stargardt, Stargardt's Disease, Stargardt Disease, STGD1
Location: Boston MA, New York NY, Baltimore MD, Durham NC,
Sponsor: Splice Bio

Sex: All

Age: 12 - 65

Code: NCT06435000

Recruiting

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A Phase 2 Efficacy and Safety Study of GAL-101, 2% Ophthalmic Solution in Non-foveal Geographic Atrophy Secondary to Non-neovascular AMD

for
Geographic Atrophy of the Macula
Location: Beverly Hills CA, Walnut Creek CA
Sponsor: Galimedix Therapeutics Inc

Sex: All

Age: 55+

Code: NCT06659549

Phase2, Recruiting

Study of BEST1 Vitelliform Macular Dystrophy

for
Best Vitelliform Macular Dystrophy, Retinitis Pigmentosa
Location: New York NY
Sponsor: Columbia University

Sex: All

Age: 0+

Code: NCT05809635

Recruiting

Rod and Cone Mediated Function in Retinal Disease

for
Retinal Degeneration, Retinitis Pigmentosa, Stargardt's Disease
Location: Bethesda MD
Sponsor: National Eye Institute (NEI)

Sex: All

Age: 5 - 70+

Code: NCT02617966

Recruiting

A Study About the Safety of a Single ASP2020 Eye Injection and if it Helps People With Vision Loss From Stargardt-type Eye Conditions

for
Stargardt Disease, Stargardt Macular Dystrophy,
Location: Cincinnati OH, Dallas TX, Phoenix AZ
Sponsor: Astellas Institute for Regenerative Medicine

Sex: All

Age: 6+

Code: NCT07734064

Phase1, Recruiting

Phase 1/2 Open-Label Dose-Escalation Study to Evaluate Safety of a Single Intravitreal Injection of RTx-021 in Patients With Stargardt Disease

for
Stargardt Disease
Location: Pittsburgh PA, Bellaire TX, Bakersfield CA
Sponsor: Ray Therapeutics, Inc.

Sex: All

Age: 16+

Code: NCT07439887

Phase1, Phase2, Recruiting

A Study to Learn How Stargardt-type Eye Conditions Progress in Children and Adults

for
Stargardt Disease, Stargardt Macular Dystrophy,
Location: Philadelphia PA, Durham NC, Miami FL, Pittsburgh PA,
Sponsor: Astellas Pharma Global Development, Inc.

Sex: All

Age: 6+

Code: NCT07425574

Recruiting

Intravitreal (IVT) Pozelimab for Geographic Atrophy (GA) in Adult Participants

for
Geographic Atrophy (GA)
Location: East Weymouth MA, The Woodlands TX, Dallas TX,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 50+

Code: NCT07230834

Phase1, Recruiting

A Study of AAVB-039 in Participants With Stargardt Disease (STGD1)

for
Stargardt Disease
Location: Jacksonville FL, Rochester MN, Bellaire TX, Dallas TX,
Sponsor: AAVantgarde Bio Srl

Sex: All

Age: 8 - 55

Code: NCT07161544

Phase1, Phase2, Recruiting

Safety and Tolerability of Subretinally Injected OPGx-BEST1 in Patients With Best Vitelliform Macular Dystrophy (BVMD) or Autosomal-Recessive Bestrophinopathy (ARB)

for
ARB, BVMD, Autosomal-Dominant Bestrophinopathy,
Location: New York NY, Cincinnati OH, Dallas TX, Los Angeles CA
Sponsor: Opus Genetics, Inc

Sex: All

Age: 18+

Code: NCT07185256

Phase1, Phase2, Recruiting

SGLT2 Inhibitors in Geographic Atrophy

for
Retinal Degeneration, Retinal Diseases, Eye Diseases,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 50+

Code: NCT07174687

Phase2, Recruiting

Cell Collection to Study Eye Diseases

for
Retinal Disease, AMD, Retinal Degeneration,
Location: Bethesda MD
Sponsor: National Eye Institute (NEI)

Sex: All

Age: 0 - 70+

Code: NCT01432847

Recruiting

Stargardt-like Macular Dystrophy (STDG3) Secondary to Mutations in ELOVL4

for
Stargardt-Like Macular Dystrophy
Location: Bethesda MD
Sponsor: National Eye Institute (NEI)

Sex: All

Age: 10 - 70+

Code: NCT04591483

Recruiting

Natural History Study of and Genetic Modifiers in Spinocerebellar Ataxias

for
Spinocerebellar Ataxia Type 1, Spinocerebellar Ataxia Type 2,
Location: Boston MA, New York NY, Montreal, Philadelphia PA,
Sponsor: Lauren Moore

Sex: All

Age: 6+

Code: NCT01060371

Recruiting

National Ophthalmic Genotyping and Phenotyping Network (eyeGENE (Registered Trademark)), Stage 3 - Expansion of DNA and Data Repositories for Rare Inherited Ophthalmic Diseases

for
Inherited Ophthalmic Diseases, Hypopigmentation Disorder,
Location: Bethesda MD
Sponsor: National Eye Institute (NEI)

Sex: All

Age: 0 - 70+

Code: NCT06491615

Recruiting
Featured

Study to Assess the Adverse Events and How Intravitreal ABBV-6628 Moves Through the Body of Adult Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration

for
Geographic Atrophy, Age-Related Macular Degeneration
Location: Carmel IN, The Woodlands TX, Dallas TX, Abilene TX,
Sponsor: AbbVie

Sex: All

Age: 50+

Code: NCT07160179

Phase1, Phase2, Recruiting