Sickle Cell Clinical Trials

Find clinical trials for sickle cell. Search for sickle cell clinical trials in different cities and states across the United States.

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Results: 88

TMLI & AlemtuzumabTMLI and Alemtuzumab for Treatment of Sickle Cell Disease

Recruiting

PHASE1

Sponsor:

City of Hope Medical Center

Location:

Duarte CA

Code:

NCT05384756

Conditions

Sickle Cell Disease

Eligibility Criteria

Sex: All

Age: 12 - 40

Healthy Volunteers: Accepted

Interventions

Alemtuzumab

Hematopoietic Cell Transplantation

Intensity-Modulated Radiation Therapy

Sirolimus

Observational StudyMeasures of Respiratory Health (MRH)

Recruiting

Sponsor:

The Hospital for Sick Children

Location:

Toronto

Code:

NCT02657837

Conditions

Cystic Fibrosis

Asthma

Sickle Cell Anemia

Bronchiolitis Obliterans

Eligibility Criteria

Sex: All

Age: 30 - 30

Healthy Volunteers: Accepted

Virtual RealityVirtual Reality As Adjunct Therapy for Vaso-Occlusive Pain

Recruiting

Sponsor:

Louisiana State University Health Sciences Center in New Orleans

Location:

New Orleans LA

Code:

NCT06773715

Conditions

Sickle Cell Disease

Vaso-occlusive Pain Episodes

Eligibility Criteria

Sex: All

Age: 8 - 21

Healthy Volunteers: Not accepted

Interventions

KindVR Aqua Program

ITU512A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease

Recruiting

PHASE1

PHASE2

Sponsor:

Novartis Pharmaceuticals

Location:

Miami FL

Code:

NCT06546670

Conditions

Sickle Cell Disease

Eligibility Criteria

Sex: All

Age: 12 - 55

Healthy Volunteers: Accepted

Interventions

ITU512

Placebo

HydroxyureaApplying Directly Observed Therapy to Hydroxyurea to Realize Effectiveness

Recruiting

Sponsor:

Nationwide Children's Hospital

Location:

Chicago IL, Columbus OH, Providence RI

Code:

NCT06264700

Conditions

Sickle Cell Disease

Eligibility Criteria

Sex: All

Age: 11+

Healthy Volunteers: Not accepted

Interventions

Video Directly Observed Therapy (VDOT)

Health Reminder Tip Alerts

Genome-edited HSPCLong-term Follow-up (LTFU) of Patients Treated With Genome-edited Autologous Hematopoietic Stem and Progenitor Cells (HSPC)

Recruiting

Sponsor:

Novartis Pharmaceuticals

Location:

Memphis TN

Code:

NCT06155500

Conditions

Sickle Cell Disease

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

OTQ923

Observational StudyLet's Get REAL: Family Health Communication Tool in Pediatric Stem Cell Transplant and Cellular Therapy

Recruiting

Sponsor:

Washington University School of Medicine

Location:

Saint Louis MO

Code:

NCT06689800

Conditions

Hematologic Malignancy

Solid Tumor

Sickle Cell Disease

Aplastic Anemia

Immune Deficiency

Eligibility Criteria

Sex: All

Age: 8+

Healthy Volunteers: Not accepted

Interventions

Let's Get REAL

Transplant with Anti-donor AntibodySickle Cell Disease Transplant Using a Nonmyeloablative Approach for Patients With Anti-donor Red Cell AntibodY

Recruiting

PHASE2

Sponsor:

Children's National Research Institute

Location:

Washington DC

Code:

NCT06358638

Conditions

Sickle Cell Disease

Eligibility Criteria

Sex: All

Age: 2 - 25

Healthy Volunteers: Not accepted

Interventions

Daratumumab

Alemtuzumab

Sirolimus

Total Body Irradiation

PanobinostatStudy of Panobinostat (LBH589) in Patients With Sickle Cell Disease

Recruiting

PHASE1

Sponsor:

Abdullah Kutlar

Location:

Augusta GA

Code:

NCT01245179

Conditions

Sickle Cell Disease

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

panobinostat

Genetics of Hematologic DiseasesInvestigation of the Genetics of Hematologic Diseases

Recruiting

Sponsor:

St. Jude Children's Research Hospital

Location:

Memphis TN

Code:

NCT02720679

Conditions

Bone Marrow Failure Syndromes

Erythrocyte Disorder

Leukocyte Disorder

Hemostasis

Blood Coagulation Disorder

Eligibility Criteria

Sex: All

Age: 0 - 70+

Healthy Volunteers: Not accepted