background image

Sickle Cell Clinical Trials

Find clinical trials for sickle cell. Search for sickle cell clinical trials in different cities and states across the United States.

Filter
1
Active & Responsive

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)

for
Sickle Cell Disease
Location: The Bronx NY, Philadelphia PA, Easton PA, Baltimore MD,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 12 - 70+

Code: NCT06439082

Phase3, Recruiting
Active & Responsive

FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases

for
Alpha-Thalassemia, Beta-Thalassemia, Amyloidosis,
Location: Los Altos CA
Sponsor: xCures

Sex: All

Age: 0+

Code: NCT06539169

Recruiting
Active & ResponsiveNew

A Study to Investigate the Effect of Mitapivat on Transfusion Burden in Subjects With Sickle Cell Disease (SCD)

for
Sickle Cell Disease
Location: Grand Rapids MI, Indianapolis IN, Flowood MS
Sponsor: Agios Pharmaceuticals, Inc.

Sex: All

Age: 12+

Code: NCT07656415

Phase3, Recruiting
Active & Responsive

Gene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease

for
Sickle Cell Disease
Location: New York NY, Columbus OH, St Louis MO, Los Angeles CA,
Sponsor: Kamau Therapeutics

Sex: All

Age: 12 - 50

Code: NCT04819841

Phase1, Phase2, Recruiting
Active & Responsive

Transplantation of Clustered Regularly Interspaced Short Palindromic Repeats Modified Hematopoietic Progenitor Stem Cells (CRISPR_SCD001) in Patients With Severe Sickle Cell Disease

for
Sickle Cell Disease
Location: Los Angeles CA, Oakland CA
Sponsor: Mark Walters, MD

Sex: All

Age: 12 - 35

Code: NCT04774536

Phase1, Phase2, Recruiting

Interested in new trials?

Get alerts for new trials in your area by subscribing now

Subscriber Image
Active & Responsive

Study of HLA-Haploidentical Stem Cell Transplantation to Treat Clinically Aggressive Sickle Cell Disease

for
Sickle Cell Disease
Location: Chicago IL
Sponsor: University of Illinois at Chicago

Sex: All

Age: 16 - 60

Code: NCT03121001

Phase2, Recruiting
Active & Responsive

Recruitment and Engagement in Care to Impact Practice Enhancement (RECIPE) for Sickle Cell Disease

for
Sickle Cell Disease
Location: Philadelphia PA, Augusta GA, Cleveland OH,
Sponsor: RTI International

Sex: All

Age: 18+

Code: NCT06385886

Recruiting
Active & Responsive

Targeting the Pathophysiology of Sickle Cell-Related Kidney Disease Using the SGLT2 Inhibitors, Empagliflozin

for
Sickle Cell Anemia (HbSS, or HbSβ-thalassemia0), Albuminuria
Location: Chicago IL
Sponsor: University of Illinois at Chicago

Sex: All

Age: 18 - 60

Code: NCT07175051

Phase2, Recruiting
Active & Responsive

Ruxolitinib-Enhanced Haplo HCT for Children and Young Adults With Sickle Cell Disease

for
Sickle Cell Disease, Hematopoetic Stem Cell Transplant,
Location: Atlanta GA
Sponsor: Arkansas Children's Hospital Research Institute

Sex: All

Age: 12 - 45

Code: NCT07252050

Phase1, Phase2, Recruiting
Active & Responsive

Myeloablative Conditioning, Prophylactic Defibrotide and Haplo AlloSCT for Patients With Sickle Cell Disease

for
Sickle Cell Disease
Location: Valhalla NY, Gainesville FL, Milwaukee WI,
Sponsor: New York Medical College

Sex: All

Age: 0 - 21

Code: NCT02675959

Phase2, Recruiting