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Small Cell Lung Cancer Clinical Trials

Browse 642 small cell lung cancer clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Phase 1 Study of OP-3136 in Advanced or Metastatic Solid Tumors

for
Advanced or Metastatic ER+ HER2- Breast Cancer (mBC),
Location: Boston MA, Sarasota FL, Grand Rapids MI, Nashville TN,
Sponsor: Olema Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT06784193

Phase1, Recruiting

Tempus Small Cell Lung Cancer Observational Study (Sculptor)

for
Small Cell Lung Cancer
Location: Baltimore MD, York PA, Chapel Hill NC, Columbus OH,
Sponsor: Tempus AI

Sex: All

Age: 18+

Code: NCT05257551

Recruiting

Safety of Pentoxifylline and Vitamin E With Stereotactic Ablative Radiotherapy (SABR) in Non-small Cell Lung Cancers

for
Non-small Cell Lung Cancers
Location: Louisville KY
Sponsor: University of Louisville

Sex: All

Age: 18+

Code: NCT01871454

Phase2, Recruiting

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC

for
Non-squamous Non-small Cell Lung Cancer
Location: Saint John, South Portland ME, West Haven CT,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06627647

Phase3, Recruiting

Trial of Therapeutic Cancer Vaccine OSE2101 in Patients With Non-Small Cell Lung Cancer and Secondary Resistance to Immune Checkpoint Inhibitor

for
Patients With Non-Small Cell Lung Cancer
Location: Rimouski, Worcester MA, Norwich CT, Patchogue NY,
Sponsor: OSE Immunotherapeutics

Sex: All

Age: 18+

Code: NCT06472245

Phase3, Recruiting

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A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

for
Advanced Non-small Cell Lung Cancer, HER2 Mutation
Location: Montreal, Fort Lauderdale FL, Toronto, Pittsburgh PA,
Sponsor: Bayer

Sex: All

Age: 18+

Code: NCT06452277

Phase3, Recruiting

A Study of Pembrolizumab With or Without Chemotherapy in Combination With Additional Treatments for Advanced Non-Small Cell Lung Cancer (NSCLC) (MK-3475-01G/KEYMAKER U01)

for
Non-small Cell Lung Cancer
Location: Philadelphia PA, Baltimore MD, Lexington KY, Fargo ND,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06731907

Phase2, Recruiting

Liver SBRT in Combination With Immune Checkpoint Inhibition in Patients With Metastatic Non-small Cell Lung Cancer

for
Liver Metastases, Non-small Cell Lung Cancer
Location: Ann Arbor MI
Sponsor: VA Ann Arbor Healthcare System

Sex: All

Age: 18+

Code: NCT05430009

Phase1, Recruiting

A Study of IBI363 in Subjects with Advanced Solid Malignancies

for
Melanoma, Non-small Cell Lung Cancer, Colorectal Cancer,
Location: Plantation FL, Ocala FL, Dearborn MI, Troy MI,
Sponsor: Innovent Biologics (Suzhou) Co. Ltd.

Sex: All

Age: 18+

Code: NCT06281678

Phase2, Recruiting

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

for
Non-small Cell Lung Cancer (NSCLC), Colorectal Cancer (CRC),
Location: Boston MA, New York NY, Baltimore MD, Fairfax VA,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT05379985

Phase1, Phase2, Recruiting

A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)

for
Non-Small Cell Lung Cancer (NSCLC)
Location: Halifax, Worcester MA, Montreal, Media PA, Newark DE,
Sponsor: Amgen

Sex: All

Age: 18 - 70+

Code: NCT05920356

Phase3, Recruiting

Neoadjuvant Dupilumab and Cemiplimab in Patients With Early-stage Resectable NSCLC

for
Non-Small Cell Lung Cancer
Location: New York NY
Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All

Age: 18+

Code: NCT06088771

Phase1, Phase2, Recruiting

Safety and Immunogenicity of Recombinant DNA and Adenovirus Expressing L523S Protein in Early Stage Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer
Location: Ocoee FL, Tyler TX, Dallas TX, Spokane WA, Seattle WA
Sponsor: Corixa Corporation

Sex: All

Age: 18+

Code: NCT00062907

Phase1, Recruiting

Study of Bevacizumab in Combination With Chemoimmunotherapy and Atezolizumab in Patients With Extensive Stage Small Cell Lung Cancer and Liver Metastases

for
Extensive-stage Small-cell Lung Cancer, Liver Metastases
Location: Ann Arbor MI, Los Angeles CA
Sponsor: Kamya Sankar

Sex: All

Age: 0+

Code: NCT05588388

Phase2, Recruiting

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

for
Advanced Solid Tumor, Melanoma, Head and Neck Cancer,
Location: New Haven CT, New York NY, Baltimore MD, Buffalo NY,
Sponsor: Daiichi Sankyo

Sex: All

Age: 18+

Code: NCT06172478

Phase2, Recruiting

Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

for
Non-small Cell Lung Cancer, Anaplastic Lymphoma Kinase-positive
Location: Boston MA, Westbury NY, New York NY, Sellersville PA,
Sponsor: Nuvalent Inc.

Sex: All

Age: 18+

Code: NCT06765109

Phase3, Recruiting

Chest Lymph Node Sampling in Patients With Advanced Lung Cancer to be Treated With Curative-intent Radiation Treatment

for
Non-Small Cell Lung Cancer
Location: Toronto, London
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Sex: All

Age: 18+

Code: NCT04852588

Recruiting

Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone in Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥ 50% (MK-2870-007)

for
Non-small Cell Lung Cancer (NSCLC)
Location: Westbrook ME, Mississauga, Brampton, Jacksonville FL,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06170788

Phase3, Recruiting

A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

for
Advanced Solid Tumor, High Grade Serous Adenocarcinoma of Ovary,
Location: Providence RI, New Haven CT, New York NY, Baltimore MD,
Sponsor: Volastra Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05902988

Phase1, Phase2, Recruiting

Quaratusugene Ozeplasmid (Reqorsa) and Atezolizumab Maintenance Therapy in ES-SCLC Patients

for
Small Cell Lung Cancer Extensive Stage
Location: Fairfax VA, Canton OH, Cincinnati OH, Fairfield OH,
Sponsor: Genprex, Inc.

Sex: All

Age: 18+

Code: NCT05703971

Phase1, Phase2, Recruiting