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Merck Clinical Trials

Find clinical trials for Merck. Search for Merck clinical trials in different cities and states across the United States.

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A Clinical Trial of MK-4082 in Healthy Participants (MK-4082-005)

for
Healthy
Location: Anaheim CA
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18 - 55

Code: NCT07697625

Phase 1, Recruiting

A Clinical Study of Belzutifan (MK-6482) and Zanzalintinib in People With Renal Cell Carcinoma (RCC) (LITESPARK-034/LS-034/MK-6482-034)

for
Carcinoma, Renal Cell
Location: Boston MA, New York NY, Morristown NJ, Ottawa,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07489495

Phase 3, Recruiting

MK-3475A±Calderasib (MK-1084) in Completely Resected Stage IIA-IIIB (N2) KRAS G12Cm NSCLC (MK-1084-013)

for
Non-small Cell Lung Cancer
Location: Moncton, Chicoutimi, Montreal
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07431827

Phase 3, Recruiting

A Clinical Trial of Ifinatamab Deruxtecan in People With Advanced Esophageal Cancer (MK-3475-06F)

for
Oesophageal Squamous Cell Carcinoma
Location: Pittsburgh PA
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07405151

Phase 1, Phase 2, Recruiting

A Clinical Study of MK-1045 in People With Non-Hodgkin Lymphoma (MK-1045-008)

for
Lymphoma, Non-Hodgkin, Lymphoma, Follicular,
Location: Montreal, Toronto, Cleveland OH, Nashville TN,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07519772

Phase 1, Phase 2, Recruiting

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A Clinical Trial of MK-7262 and Enlicitide in Participants With High Lipoprotein(a) (MK-7262-004)

for
Lipoprotein(a)
Location: Quebec, Waterbury CT, Chicoutimi, Rosedale NY,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07614984

Phase 2, Recruiting

A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)

for
Renal Cell Carcinoma
Location: Westbrook ME, Baltimore MD, Charlotte NC, Knoxville TN,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07227402

Phase 3, Recruiting

Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015)

for
Psoriatic Arthritis
Location: Rimouski, Brooklyn NY, Trois-Rivieres, Philadelphia PA,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18 - 70+

Code: NCT07486960

Phase 2, Recruiting

A Clinical Trial of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) to Treat Urothelial Cancer (MK-2870-031)

for
Bladder Cancer
Location: Boston MA, Quebec, New York NY, Morristown NJ,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07419295

Phase 3, Recruiting

Extension Study for Participants in Studies That Include Belzutifan (MK-6482-043/LITESPARK-043)

for
Von Hippel-Lindau Disease, Malignant Neoplasms
Location: Boston MA, Philadelphia PA, Detroit MI, Nashville TN,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07405164

Phase 3, Recruiting

A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)

for
Ovarian Neoplasms, Ovarian Cancer
Location: Scarborough ME, Providence RI, Chicoutimi, New York NY,
Sponsor: Merck Sharp & Dohme LLC

Sex: Female

Age: 18+

Code: NCT07318558

Phase 3, Recruiting

A Study of Intismeran Autogene (V940)/Placebo + Pembrolizumab and Chemotherapy in Metastatic Squamous Non-Small Cell Lung Cancer (V940-013)

for
Squamous Non-small Cell Lung Cancer
Location: Paramus NJ, Albany NY, Fairfax VA, Tampa FL,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07221474

Phase 2, Recruiting

Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)

for
Esophageal Squamous Cell Carcinoma
Location: Pittsburgh PA
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06780111

Phase 1, Phase 2, Recruiting

A Clinical Study of Novel Pneumococcal Vaccine V118C in Children (V118C-002)

for
Pneumococcal Infection
Location: Columbia MD, East Syracuse NY, Charlottesville VA,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 0 - 1

Code: NCT07300267

Phase 1, Recruiting

A Clinical Study of Calderasib (MK-1084) in People With Advanced Solid Tumors (MK-1084-014)

for
Neoplasm Malignant
Location: New Brunswick NJ, Montreal, Baltimore MD, Ottawa,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07209111

Phase 2, Recruiting

A Study to Evaluate the Safety and Efficacy of MK-1406/CD388 for Prevention of Influenza (MK-1406-005/CD388.SQ.3.06)

for
Influenza
Location: Burlington MA, Bridgeport CT, Brooklyn NY, Annapolis MD,
Sponsor: Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

Sex: All

Age: 12+

Code: NCT07159763

Phase 3, Recruiting

A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) as First-line Maintenance Treatment of Cervical Cancer (MK-2870-036/TroFuse-036/GOG-3123/ENGOT-cx22)

for
Cervical Cancer
Location: Halifax, Providence RI, Quebec, Sherbrooke, Mineola NY,
Sponsor: Merck Sharp & Dohme LLC

Sex: Female

Age: 18+

Code: NCT07216703

Phase 3, Recruiting

Safety and Immunogenicity of V540B in Healthy Adults (V540B-002).

for
Healthy
Location: Hallandale FL, Hollywood FL
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18 - 45

Code: NCT06623409

Phase 1, Recruiting

A Clinical Study of MK-3120 in People With Bladder Cancer (MK-3120-003)

for
Bladder Cancer, Urinary Bladder Neoplasms
Location: Quebec, New Brunswick NJ, Myrtle Beach SC, Austin TX,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07222488

Phase 1, Phase 2, Recruiting

A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)

for
Castration-Resistant Prostatic Cancer, Metastasis
Location: Sherbrooke, New York NY, Montreal, Washington D.C. DC,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06863272

Phase 1, Phase 2, Recruiting