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Paid Clinical Trials Costa Mesa

Discover 3,561 paid clinical trials in Costa Mesa, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Study of OsrhAAT or Placebo in Healthy Volunteers

for
Emphysema Secondary to Congenital AATD
Location: Cypress CA
Sponsor: Healthgen Biotechnology Corp.

Sex: All

Age: 18 - 55

Code: NCT05315921

Phase1, Recruiting

A Study of Efficacy, Safety, Tolerability of LXE408 in Participants With Chronic Chagas Disease.

for
Chagas Disease
Location: Sylmar CA, Houston TX, Gainesville FL, Boston MA
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18 - 60

Code: NCT06632600

Phase2, Recruiting
New

A Research Study on How UBT251 Affects Levels of Midazolam, Caffeine and Warfarin in the Blood of Participants With Excess Body Weight

for
Obesity, Overweight
Location: Cypress CA
Sponsor: Novo Nordisk A/S

Sex: All

Age: 18 - 65

Code: NCT07710768

Phase1, Recruiting

A Study of Dotinurad Versus Allopurinol in Participants With Gout

for
Gout
Location: Norco CA, Covina CA, Menifee CA, Tujunga CA,
Sponsor: Crystalys Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT07089875

Phase3, Recruiting

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4248 in Healthy Participants and Participants With Chronic Kidney Disease and Type 2 Diabetes and to Assess Home Measurements of Creatinine in a Non Interventional Cohort

for
Chronic Kidney Disease
Location: Glendale CA, San Antonio TX, Saint Paul MN, Chicago IL
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT07024823

Phase1, Recruiting

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A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed (EMBOLD PanGI-201)

for
Gastrointestinal Neoplasms
Location: Whittier CA, Los Alamitos CA, Los Angeles CA,
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT06885034

Phase1, Phase2, Recruiting

Zanubrutinib in Combination With Odronextamab for the Treatment of Patients With Richter's Transformation

for
Recurrent Transformed Chronic Lymphocytic Leukemia,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06735664

Phase1, Recruiting

A Study to Evaluate the Pharmacokinetics (PK) and Safety of a Single Dose of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Normal Hepatic Function and Participants With Hepatic Impairment

for
Hepatic Impairment
Location: Lake Forest CA, San Dimas CA, San Antonio TX,
Sponsor: Insmed Incorporated

Sex: All

Age: 18 - 70

Code: NCT07643155

Phase1, Recruiting

Improving Behavioral Health for Caregivers and Children After Pediatric Injury

for
Quality of Life, PTSD, Depression Not Otherwise Specified,
Location: Los Angeles CA, Houston TX, Lexington KY, Ann Arbor MI
Sponsor: Medical University of South Carolina

Sex: All

Age: 18+

Code: NCT06856057

Recruiting

Assessing Improvements in Mood and Sleep Trial

for
Depression, Suicidality, Sleep
Location: Los Angeles CA, Augusta GA, Pittsburgh PA
Sponsor: University of Pittsburgh

Sex: All

Age: 55+

Code: NCT06639477

Recruiting

REGN7508 Versus Apixaban and Enoxaparin for Thromboprophylaxis After Total Knee Arthroplasty in Adults

for
Venous Thromboembolism (VTE)
Location: Riverside CA, St. George UT, Englewood CO,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07015905

Phase3, Recruiting

A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)

for
Heart Failure
Location: Lake Forest CA, Beverly Hills CA, Santa Maria CA,
Sponsor: Pfizer

Sex: All

Age: 18 - 70+

Code: NCT06991257

Phase2, Recruiting

Fimepinostat, Combination HDAC and Pi3-kinase Inhibitor Tumor-Directed Therapy for Cushing Disease

for
Cushing Disease
Location: Los Angeles CA
Sponsor: University of California, Los Angeles

Sex: All

Age: 18+

Code: NCT05971758

Phase2, Recruiting

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Encinitas CA, La Jolla CA, San Diego CA, Surprise AZ,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT06532279

Phase2, Recruiting

A Prospective, US-based Study Assessing Mogamulizumab-associated Rash in Patients Diagnosed With Mycosis Fungoides or Sezary Syndrome and Treated With Standard of Care Mogamulizumab

for
Recurrent Mycosis Fungoides, Recurrent Sezary Syndrome,
Location: Duarte CA, St Louis MO
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07003100

Recruiting

Transcatheter Fontan Stenting: Impact on Hepatic Stiffness and Exercise Capacity

for
Single-ventricle, Stenosis
Location: Los Angeles CA
Sponsor: Children's Hospital Los Angeles

Sex: All

Age: 12 - 21

Code: NCT07073612

Recruiting

Global Trial in APG2575 for Patients With CLL/SLL

for
CLL/SLL
Location: Anaheim CA, Tuscon AZ, Houston TX, Kingswood TX,
Sponsor: Ascentage Pharma Group Inc.

Sex: All

Age: 18 - 70+

Code: NCT06104566

Phase3, Recruiting

Ultra-hypofractionated Whole Breast Irradiation With Lumpectomy Cavity Boost for the Treatment of Stage I-III Breast Cancer

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Torrance CA, Duarte CA, Arcadia CA, Upland CA,
Sponsor: City of Hope Medical Center

Sex: Female

Age: 40+

Code: NCT06954831

Phase2, Recruiting

Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma

for
High Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements,
Location: Los Angeles CA, Tucson AZ, Portland OR, Anaconda MT,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06649812

Phase2, Recruiting
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A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease

for
Colorectal Cancer
Location: Fullerton CA, Los Angeles CA, Portland OR,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07023289

Phase2, Recruiting