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Paid Clinical Trials Costa Mesa

Discover 3,599 paid clinical trials in Costa Mesa, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

Global Patient Registry to Monitor Long-term Safety and Effectiveness of Increlex® in Children and Adolescents With Severe Primary Insulin-like Growth Factor-1 Deficiency (SPIGFD).

for
IGF1 Deficiency
Location: Orange CA, Cincinnati OH, Miami FL
Sponsor: Esteve Pharmaceuticals, S.A.

Sex: All

Age: 2 - 18

Code: NCT00903110

Recruiting
Active & Responsive

A First-in-human Study of S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic Encephalopathy

for
Epileptic Encephalopathy
Location: Orange CA, Columbus OH, Boston MA
Sponsor: Institut de Recherches Internationales Servier

Sex: All

Age: 2 - 12

Code: NCT07227857

Phase 1, Phase 2, Recruiting
Active & Responsive

A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors

for
Pediatric Tumor of CNS, Pediatric Tumor of Brain,
Location: Orange CA
Sponsor: Neonc Technologies, Inc.

Sex: All

Age: 5 - 18

Code: NCT06357377

Phase 1, Recruiting
Active & Responsive

TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II

for
Lymphoblastic Leukemia
Location: Orange CA, Los Angeles CA, Madera CA, Phoenix AZ,
Sponsor: Tanja Andrea Gruber

Sex: All

Age: 0 - 1

Code: NCT05848687

Phase 1, Phase 2, Recruiting
Active & Responsive

Ph II Intraperitoneal Paclitaxel + System Therapy in GI Ca w/Peritoneal Carcinomatosis (STOPGAP-B)

for
Esophageal Carcinoma, Gastric Cancer (Diagnosis),
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT07795749

Phase 2, Recruiting

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Active & Responsive

Effect of NAC on Preventing Chemo-Related Cognitive Impairments in Ovarian Ca Pts Treated W/ PBT

for
Ovarian Cancer, Cognitive Impairment
Location: Orange CA
Sponsor: University of California, Irvine

Sex: Female

Age: 18+

Code: NCT04520139

Phase 1, Phase 2, Recruiting
Active & Responsive

A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

for
Colorectal Cancer
Location: Orange VA, Whittier CA, Los Angeles CA, La Jolla CA,
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT06562543

Recruiting
Active & Responsive

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)

for
Sickle Cell Disease
Location: Orange CA, Houston TX, Flowood MS, Chicago IL,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 12 - 70+

Code: NCT06439082

Phase 3, Recruiting
Active & Responsive

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

for
Glioblastoma
Location: Orange CA, Los Angeles CA, La Jolla CA,
Sponsor: Global Coalition for Adaptive Research

Sex: All

Age: 18+

Code: NCT03970447

Phase 2, Phase 3, Recruiting
Active & Responsive

ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

for
Major Depressive Disorder (MDD),
Location: Orange CA, Chino CA, Glendale CA, West Hills CA,
Sponsor: ACADIA Pharmaceuticals Inc.

Sex: All

Age: 18 - 65

Code: NCT07284667

Phase 2, Recruiting
Active & Responsive

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

for
Crohn's Disease
Location: Orange CA, Anaheim CA, Los Angeles CA, Lancaster CA,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 16 - 70+

Code: NCT06430801

Phase 3, Recruiting
Active & Responsive

ANCHOR Study: A Study to Assess the Safety and Efficacy of ABBV-CLS-628 in Adult Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)

for
Autosomal Dominant Polycystic Kidney Disease
Location: Orange CA, Huntington Park CA, Los Angeles CA,
Sponsor: Calico Life Sciences LLC

Sex: All

Age: 18 - 55

Code: NCT06902558

Phase 2, Recruiting
Active & Responsive

Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network

for
Genetic Disease
Location: Orange CA, Stanford CA, Seattle WA, Houston TX,
Sponsor: National Human Genome Research Institute (NHGRI)

Sex: All

Age: 0 - 70+

Code: NCT02450851

Recruiting
Active & Responsive

Evaluation of a Non-Implanted Electrical Stimulation Device for Overactive Bladder (OAB)

for
Overactive Bladder (OAB)
Location: Orange CA, Beverly Hills CA, Los Angeles CA,
Sponsor: FemPulse Corporation

Sex: Female

Age: 21+

Code: NCT07195656

Recruiting
Active & Responsive

A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer

for
Gastric Adenocarcinoma,
Location: Orange CA, Seattle WA, Dallas TX, Westwood KS,
Sponsor: Astellas Pharma Global Development, Inc.

Sex: All

Age: 18+

Code: NCT05365581

Phase 1, Recruiting
Active & Responsive

Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))

for
Mesial Temporal Lobe Epilepsy
Location: Orange CA, Los Angeles CA, San Diego CA, Phoenix AZ,
Sponsor: Neurona Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT05135091

Phase 3, Recruiting
Active & Responsive

A Substudy of Investigational Agents in Programmed Cell Death-1/Ligand 1 (PD-1/L1) Refractory Locally Advanced or Metastatic Urothelial Carcinoma (mUC) (MK-3475-04A)

for
Urothelial Carcinoma
Location: Orange CA, San Francisco CA, Salt Lake City UT,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT05562830

Phase 1, Phase 2, Recruiting
Active & Responsive

A Study of TAK-505 in Adults With Solid Tumors

for
Malignant Solid Tumors
Location: Orange CA, San Antonio TX, Dallas TX, Houston TX,
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT07436728

Phase 1, Phase 2, Recruiting
Active & Responsive

Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies

for
AML (Acute Myeloid Leukemia), Glioma, Cholangiocarcinoma,
Location: Orange CA, New York NY
Sponsor: Rigel Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07486713

Recruiting
Active & Responsive

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

for
Glioblastoma (GBM), Newly Diagnosed Glioblastoma, GBM,
Location: Orange CA, Los Angeles CA, La Jolla CA, Palo Alto CA,
Sponsor: Black Diamond Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07326566

Phase 2, Recruiting