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Paid Clinical Trials Orange County

Discover 3,622 paid clinical trials in Orange County, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

for
Colorectal Neoplasms
Location: Los Alamitos CA, Torrance CA, Los Angeles CA,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT06750094

Phase 3, Recruiting

High Cardiovascular Risk Intervention With Cardio-Oncology Consultation for Prostate Cancer Following Androgen Receptor Pathway Inhibitor (ARPI) Therapy (Heart-Safe)

for
Prostate Cancer (Diagnosis), Prostate Cancer Stage IV, CV Risk
Location: Los Angeles CA
Sponsor: Cedars-Sinai Medical Center

Sex: Male

Age: 45+

Code: NCT07223385

Phase 2, Recruiting

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

for
Colorectal Neoplasms
Location: Los Alamitos CA, Torrance CA, Los Angeles CA,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT06662786

Phase 3, Recruiting

Minimally Invasive Neuroendoscopic Ultra-Early Targeted ICH Evacuation

for
Basal Ganglia Intracerebral Hemorrhage
Location: Los Angeles CA, Temple TX, Tampa FL, New Brunswick NJ,
Sponsor: Weill Medical College of Cornell University

Sex: All

Age: 18 - 70+

Code: NCT07260916

Recruiting

Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants With Upper Limb Essential Tremor

for
Upper Limb Essential Tremor
Location: Fullerton CA, Carlsbad CA, Fresno CA, Spokane WA,
Sponsor: AbbVie

Sex: All

Age: 18 - 70+

Code: NCT07673107

Phase 2, Recruiting

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A Clinical Trial of MK-1045 and Rituximab in People With Follicular Lymphoma (MK-1045-007)

for
Follicular Lymphoma
Location: Duarte CA, Nashville TN, Lexington KY, Cleveland OH,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07634471

Phase 2, Phase 3, Recruiting

An Exploratory Efficacy and Safety Study of DFL24498 Topical Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye Disease

for
Dry Eye Disease (DED)
Location: Newport Beach CA, Azusa CA, Torrance CA, Inglewood CA,
Sponsor: Dompé Farmaceutici S.p.A

Sex: All

Age: 18+

Code: NCT07503886

Phase 2, Recruiting

An Investigational Study of BGB-58067 As a Single Agent and in Combination With Anticancer Agents in Participants With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: Los Alamitos CA, Los Angeles CA, Irving TX, Houston TX,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT06589596

Phase 1, Recruiting

A Phase 2a Study of ALN-PNP With and Without a GLP1R Agonist in Adult Patients With Homozygous PNPLA3-Related MASLD

for
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD),
Location: Pasadena CA, Coronado CA, Tucson AZ, San Antonio TX,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT07527910

Phase 2, Recruiting

A Phase 1/2a Study of DB-2304 in Healthy Adults and SLE/CLE Participants

for
Systemic Lupus Erythematosus (SLE) or Cutaneous Lupus Erythematosus,
Location: La Palma CA, San Antonio TX, Irving TX, Clearwater FL,
Sponsor: DualityBio Inc.

Sex: All

Age: 18 - 70

Code: NCT06625671

Phase 1, Phase 2, Recruiting

A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer

for
Breast Neoplasms
Location: Los Angeles CA, Loveland CO, Portland OR, Greeley CO,
Sponsor: Eli Lilly and Company

Sex: Female

Age: 18+

Code: NCT07287098

Phase 2, Recruiting

A Study to Evaluate the Treatment Outcomes of Subcutaneous Anifrolumab in Immunosuppressant-naïve and Biologic-naïve Systemic Lupus Erythematosus

for
Systemic Lupus Erythematosus
Location: La Palma CA, Menifee CA, Temecula CA, La Jolla CA,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70

Code: NCT07430306

Phase 3, Recruiting

An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative Colitis

for
Colitis, Ulcerative
Location: Los Alamitos CA, La Jolla CA, Mesa AZ, Littleton CO,
Sponsor: Pfizer

Sex: All

Age: 18 - 64

Code: NCT06398626

Recruiting

Impact of Lactation Antenatal Teaching by Clinicians and Healthcare Providers

for
Pregnancy Related, Breast Feeding, Exclusive
Location: Loma Linda CA
Sponsor: Loma Linda University

Sex: Female

Age: 18 - 45

Code: NCT07560553

Recruiting

PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney Disease

for
Proteinuric Kidney Diseases
Location: Los Angeles CA, Glendale CA, Granada Hills CA,
Sponsor: Boehringer Ingelheim

Sex: All

Age: 12+

Code: NCT07355296

Phase 2, Recruiting

A Trial Evaluating AMG 127 in Healthy Participants and Participants With Type 2 Diabetes Mellitus

for
Diabetes Mellitus, Type 2
Location: Lake Forest CA, Aventura FL
Sponsor: Amgen

Sex: All

Age: 18 - 70+

Code: NCT07590193

Phase 1, Recruiting

Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

for
Non-small Cell Lung Cancer (NSCLC)
Location: Irvine CA, Duarte CA, Los Angeles CA, Loma Linda CA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07291037

Phase 3, Recruiting

A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

for
Metastatic Gastric Adenocarcinoma,
Location: Los Alamitos CA, Las Vegas NV, Chandler AZ,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT07043400

Phase 3, Recruiting

Study to Learn About Safety, Tolerability, and Immune Response of a Catch-up Pneumococcal Vaccine in Children and Adolescents

for
Pneumococcal Disease
Location: Ontario CA, Fair Oaks CA, West Jordan UT, Layton UT,
Sponsor: Pfizer

Sex: All

Age: 1 - 17

Code: NCT07660198

Phase 3, Recruiting

Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors

for
Ovarian Cancer, Lung Adenocarcinoma, Endometrial Cancer,
Location: Irvine CA, Duarte CA, Aurora CO, Portland OR,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT05797168

Phase 1, Phase 2, Recruiting