Discover 3,560 paid clinical trials in Orange County, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Orange County offers clinical trials for a variety of conditions, including high blood pressure, heart disease, and skin disorders such as eczema, alopecia, and psoriasis. The city’s medical institutions are actively recruiting both healthy volunteers, as well as those with specific health needs to participate in studies that could improve treatments and outcomes for these, and many other widespread health issues.
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Results: 3,560
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
for
Triple Negative Breast Cancer
Location: Newport Beach CA, Downey CA, San Francisco CA,
Sponsor: Gilead Sciences
Sex: All
Age: 18+
Code: NCT05633654
Phase3, Recruiting
Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)
Location: Newport Beach CA, Fullerton CA, Mission Viejo CA,
Sponsor: HistoSonics, Inc.
Sex: All
Age: 22+
Code: NCT06486454
Recruiting
18F-DCFPyL PET-CT Scan and Prostate Cancer
for
Prostate Cancer Adenocarcinoma
Location: Los Angeles CA
Sponsor: Lida Jafari
Sex: Male
Age: 18+
Code: NCT03852654
Phase2, Phase3, Recruiting
Mobile Application to Improve Health-Related Outcomes in Patients With Advanced Lung Cancer
for
Lung Cancer
Location: Los Angeles CA, Boston MA
Sponsor: Massachusetts General Hospital
Sex: All
Age: 18+
Code: NCT06427954
Recruiting
A Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors
for
Advanced Solid Tumors, Colorectal Cancer
Location: Irvine CA, Duarte CA, Los Angeles CA,
Sponsor: Vividion Therapeutics, Inc.
Sex: All
Age: 18+
Code: NCT06004245
Phase1, Recruiting
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Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer
Location: Irvine CA, Long Beach CA, Duarte CA, Upland CA,
Sponsor: Pfizer
Sex: All
Age: 18+
Code: NCT07421700
Phase1, Phase2, Recruiting
Repurposing Nucleoside Reverse Transcriptase Inhibitors for Treatment of AD
for
Alzheimer Disease, Early Onset, Mild Cognitive Impairment,
Location: Los Angeles CA, Providence RI
Sponsor: Butler Hospital
Sex: All
Age: 50 - 70+
Code: NCT04500847
Phase1, Recruiting
A Study of Neoadjuvant Amivantamab With Either Lazertinib or Chemotherapy in Participants With Resectable EGFR-Mutated NSCLC
for
Carcinoma, Non-Small-Cell Lung
Location: Irvine CA, Duarte CA, Portland OR, Toronto
Sponsor: Janssen Research & Development, LLC
Sex: All
Age: 18+
Code: NCT07586202
Phase2, Recruiting
AZD0305 as Monotherapy or in Combination With Anticancer Agents in Participants With Multiple Myeloma
for
Multiple Myeloma
Location: Irvine CA, Duarte CA, Atlanta GA, Ann Arbor MI,
Sponsor: AstraZeneca
Sex: All
Age: 18+
Code: NCT06106945
Phase1, Phase2, Recruiting
Ca-Mg Butyrate in GWI
for
Gulf War Illness, Chronic Fatigue, Neurocognitive Dysfunction
Location: Long Beach CA, Salt Lake City UT, Miami FL
Sponsor: VA Office of Research and Development
Sex: All
Age: 40 - 70
Code: NCT05367245
Phase2, Recruiting
Bromelain, Comosain as a New Drug for Treating and Preventing Various Types of Cancer in the Humans
for
Cancer
Location: West Covina CA
Sponsor: Oeyama-Moto Cancer Research Foundation
Sex: All
Age: 18 - 70+
Code: NCT02340845
Phase2, Recruiting
Characterization of T-cell Repertoire in Patients With Acute Myeloid Leukemia Undergoing Donor Stem Cell Transplant
for
Acute Myeloid Leukemia
Location: Los Angeles CA
Sponsor: University of Southern California
Sex: All
Age: 18+
Code: NCT03921047
Recruiting
Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects
for
Migraine
Location: Hawthorne CA, Boise ID, San Antonio TX, Grand Island NE,
Sponsor: Pfizer
Sex: All
Age: 6 - 17
Code: NCT05156398
Phase3, Recruiting
Determining Efficacy and Safety of BXCL501 in Agitation Associated With Pediatric Schizophrenia and Bipolar Disorder
for
Schizophrenia, Schizo-Affective Disorder,
Location: Anaheim CA, DeSoto TX, Decatur GA, Hialeah FL
Sponsor: BioXcel Therapeutics Inc
Sex: All
Age: 10 - 17
Code: NCT05025605
Phase1, Recruiting
A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line (2L) + Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (MK-1026-010/BELLWAVE-010).
for
Leukemia, Lymphocytic, Chronic, B-Cell,
Location: Long Beach CA, Reno NV, Portland OR, Olympia WA,
Sponsor: Merck Sharp & Dohme LLC
Sex: All
Age: 18+
Code: NCT05947851
Phase3, Recruiting
Phase 2 Study of Combination Tivozanib and Nivolumab in Advanced Non-Clear Cell Renal Cell Carcinoma
for
Renal Cell Carcinoma
Location: Irvine CA, Dallas TX, Houston TX, Ann Arbor MI,
Sponsor: M.D. Anderson Cancer Center
Sex: All
Age: 18+
Code: NCT06053658
Phase2, Recruiting
Outpatient Labor Induction With the Transcervical Foley Balloon
for
Pregnancy, Labor; Forced or Induced, Affecting Fetus or Newborn
Location: Los Angeles CA
Sponsor: University of Southern California
Sex: Female
Age: 18+
Code: NCT02210598
Recruiting
Determining the Role of Social Reward Learning in Social Anhedonia
for
Psychosis
Location: Los Angeles CA, Birmingham AL
Sponsor: University of Alabama at Birmingham
Sex: All
Age: 18 - 35
Code: NCT05617898
Recruiting
Minimal Residual Disease Testing for the Early Detection of Cancer Recurrence in Resectable Stage II-IV Colorectal Cancer Patients
for
Resectable Colorectal Carcinoma,
Location: Huntington Beach CA, Newport Beach CA, Irvine CA,
Sponsor: City of Hope Medical Center
Sex: All
Age: 18+
Code: NCT07125729
Recruiting
A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)
for
Diffuse Large B-Cell Lymphoma
Location: Fullerton CA, Los Alamitos CA, Long Beach CA,