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Paid Clinical Trials Orange County

Discover 3,614 paid clinical trials in Orange County, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

for
Solid Tumors, Advanced Cancer, Renal Cancer, Gastric Cancer,
Location: Los Angeles CA, Edmonton, Winnipeg, Madison WI, Toronto,
Sponsor: Apollomics Inc.

Sex: All

Age: 18+

Code: NCT03175224

Phase 2, Recruiting

Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)

for
Acute Decompensated Heart Failure
Location: Irvine CA, Long Beach CA, Sacramento CA,
Sponsor: Reprieve Cardiovascular, Inc

Sex: All

Age: 22+

Code: NCT06898515

Recruiting

Study to Assess the Efficacy and Safety of IMVT-1402 in Participants With Mild to Severe Generalized Myasthenia Gravis

for
Generalized Myasthenia Gravis
Location: Irvine CA, Los Angeles CA, Carlsbad CA,
Sponsor: Immunovant Sciences GmbH

Sex: All

Age: 18 - 70+

Code: NCT07039916

Phase 3, Recruiting

A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma

for
Endometrial Adenocarcinoma
Location: Newport Beach CA, Duarte CA, Los Angeles CA,
Sponsor: Acrivon Therapeutics

Sex: Female

Age: 18+

Code: NCT05548296

Phase 2, Recruiting

Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults And Adolescent Participants Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)

for
Central Line Associated Blood Stream Infections (CLABSI)
Location: Los Angeles CA, Omaha NE, Sugarland TX, Rochester MN,
Sponsor: CorMedix Therapeutics

Sex: All

Age: 12+

Code: NCT06822426

Phase 3, Recruiting

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Evaluation of Cross-Linked Polyelectrolyte (CLP) With Placebo in Heart Failure Subjects

for
Heart Failure
Location: Tustin CA
Sponsor: Sorbent Therapeutics

Sex: All

Age: 21+

Code: NCT01736735

Phase 2, Recruiting

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

for
Lymphoma, Non-Hodgkin, Multiple Myeloma, Advanced Solid Tumors
Location: Los Angeles CA, Santa Barbara CA, Phoenix AZ,
Sponsor: American Society of Clinical Oncology

Sex: All

Age: 12+

Code: NCT02693535

Phase 2, Recruiting

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

for
Locally Advanced Lung Non-Small Cell Carcinoma,
Location: Los Angeles CA, Bakersfield CA, Kingman AZ, Modesto CA,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT05624996

Phase 3, Recruiting

Wearable Device and Behavioral Support for Enhancing Arm Use After Stroke

for
Chronic Stroke Patients
Location: Irvine CA
Sponsor: University of California, Irvine

Sex: All

Age: 18 - 70+

Code: NCT07042152

Recruiting

Adapting Lifestyle Offloading for DFUs

for
Diabetic Foot Ulcer, Diabetic Foot
Location: Los Angeles CA
Sponsor: University of Southern California

Sex: All

Age: 21+

Code: NCT06278935

Recruiting

A Study to Evaluate Safety, Tolerability, and Efficacy of AB-1009 Gene Therapy (GAA Gene) in Adult Participants With Late-Onset Pompe Disease (PROGRESS-GT LOPD)

for
Pompe Disease (Late-onset), Pompe Disease Late-Onset, LOPD
Location: Irvine CA, Dallas TX, Pittsburgh PA, Durham NC,
Sponsor: AskBio Inc

Sex: All

Age: 18 - 65

Code: NCT07282847

Phase 1, Phase 2, Recruiting

PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR

for
Aortic Stenosis, Calcific, Aortic Valve Stenosis
Location: Los Angeles CA, Rancho Mirage CA, Santa Barbara CA,
Sponsor: Edwards Lifesciences

Sex: All

Age: 65+

Code: NCT04889872

Recruiting

A Study Exploring Changes in a Variety of Biomarkers Following Dosing With MT1988 in Participants at Clinical High Risk for Psychosis

for
Clinical High Risk for Psychosis (CHR)
Location: Irvine CA, Los Angeles CA, San Francisco CA, Eugene OR,
Sponsor: Monument Therapeutics Limited

Sex: All

Age: 17 - 30

Code: NCT07226895

Phase 1, Phase 2, Recruiting

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

for
Recurrent Lung Non-Small Cell Carcinoma,
Location: Torrance CA, Beverly Hills CA, Los Angeles CA,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT05642572

Phase 2, Recruiting

Safety and Tolerability Study of Human Neural Stem Cells for Huntington's Disease

for
Huntington Disease
Location: Irvine CA
Sponsor: Leslie Thompson

Sex: All

Age: 18 - 65

Code: NCT07451613

Phase 1, Phase 2, Recruiting

Prospective Data Registry and Quality of Life Assessment of Patients Undergoing Radiotherapy With the RefleXion Medical Radiotherapy System

for
Cancer, Cancer Central Nervous System, Cancer Thoracic,
Location: Duarte CA, Palo Alto CA, Dallas TX, Pittsburgh PA,
Sponsor: RefleXion Medical

Sex: All

Age: 0+

Code: NCT05406167

Recruiting

Papaverine in Combination With Chemoradiation for the Treatment of Stage II-III Non-small Cell Lung Cancer

for
Locally Advanced Lung Non-Small Cell Carcinoma,
Location: Duarte CA, Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT05136846

Phase 1, Recruiting

Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement

for
Aortic Stenosis, Coronary Artery Disease, Coronary Stenosis
Location: Torrance CA, Redlands CA, Santa Barbara CA, Phoenix AZ,
Sponsor: University of British Columbia

Sex: All

Age: 0+

Code: NCT04634240

Recruiting

Ruxolitinib With De-Intensified HLH-94 for the Treatment of Hemophagocytic Lymphohistiocytosis (HLH)

for
Hemophagocytic Lymphohistiocytoses
Location: Irvine CA, San Diego CA, San Francisco CA,
Sponsor: Jerry Lee, MD, MSc, MPhil

Sex: All

Age: 18+

Code: NCT06160791

Phase 2, Recruiting

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

for
Endometrial Cancer
Location: Irvine CA, Duarte CA, La Jolla CA, Eugene OR,
Sponsor: AstraZeneca

Sex: Female

Age: 18+

Code: NCT06989112

Phase 3, Recruiting