Discover 3,617 paid clinical trials in Orange County, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Orange County offers clinical trials for a variety of conditions, including high blood pressure, heart disease, and skin disorders such as eczema, alopecia, and psoriasis. The city’s medical institutions are actively recruiting both healthy volunteers, as well as those with specific health needs to participate in studies that could improve treatments and outcomes for these, and many other widespread health issues.
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Results: 3,617
A Study of VARIPULSE Pulsed Field Ablation (PFA) Catheter and FARAWAVE PFA Catheter in the Treatment of Participants With Persistent Atrial Fibrillation
for
Atrial Fibrillation
Location: Fountain Valley CA, Ventura CA, Murray UT, Austin TX,
Sponsor: Biosense Webster, Inc.
Sex: All
Age: 18 - 70+
Code: NCT07523750
Recruiting
A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)
for
Non-Small Cell Lung Cancer (NSCLC)
Location: Fountain Valley CA, Los Alamitos CA, Beverly Hills CA,
Sponsor: Bristol-Myers Squibb
Sex: All
Age: 18+
Code: NCT07361510
Phase 3, Recruiting
SBRT Boost for Unfavorable Prostate Cancer'
for
Prostate Cancer
Location: Fountain Valley CA, Laguna Hills CA, Long Beach CA
Sponsor: MemorialCare Health System
Sex: Male
Age: 18+
Code: NCT02016248
Recruiting
A Study Assessing Long-Term Safety and Effectiveness in Treatment Management of Atrial Fibrillation With VARIPULSE Catheter System
for
Atrial Fibrillation
Location: Fountain Valley CA, Ventura CA, Phoenix AZ, Tucson AZ,
Sponsor: Biosense Webster, Inc.
Sex: All
Age: 22+
Code: NCT07227532
Recruiting
Study of Trastuzumab Deruxtecan, Pembrolizumab, and Platinum-based Chemotherapy in First-line HER2 Overexpressing Non-small Cell Lung Cancer
for
Non-small Cell Lung Cancer
Location: Fountain Valley CA, Los Angeles CA, Reno NV,
Sponsor: Daiichi Sankyo
Sex: All
Age: 18+
Code: NCT06899126
Phase 3, Recruiting
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A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)
for
Colon Adenocarcinoma, Rectal Adenocarcinoma
Location: Fountain Valley CA, Los Angeles CA, Santa Monica CA,
Sponsor: Merck Sharp & Dohme LLC
Sex: All
Age: 18+
Code: NCT06997497
Phase 3, Recruiting
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
for
CRC (Colorectal Cancer)
Location: Fountain Valley CA, Fullerton CA, Los Alamitos CA,
Location: Fountain Valley CA, Pasadena CA, Los Angeles CA,
Sponsor: Hamilton Health Sciences Corporation
Sex: All
Age: 18+
Code: NCT05963698
Recruiting
Clinical Trial of N-803 Plus Tislelizumab or Prior Failed Immune Checkpoint Inhibitor and Docetaxel Versus Docetaxel Monotherapy in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Acquired Resistance to Immune Checkpoint Inhibitor Therapy
for
NSCLC Stage IV
Location: Fountain Valley CA, Irvine CA, Newport Beach CA,
Sponsor: ImmunityBio, Inc.
Sex: All
Age: 18 - 70+
Code: NCT06745908
Phase 3, Recruiting
A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications
for
Parkinson's Disease
Location: Fountain Valley CA, Los Angeles CA, Phoenix AZ,
Sponsor: Bayer
Sex: All
Age: 45 - 70+
Code: NCT07330258
Recruiting
A Study of Buntanetap in Participants With PD
for
Parkinson's Disease (PD), Deep Brain Stimulation
Location: Fountain Valley CA, Sun City AZ, Englewood CO,
Sponsor: Annovis Bio Inc.
Sex: All
Age: 40 - 70+
Code: NCT07284784
Phase 2, Phase 3, Recruiting
Low-dose Carbon Monoxide (HBI-002) Trial to Evaluate Safety, Tolerability, PK, and Biomarkers in Parkinson's Disease
for
Parkinson Disease
Location: Fountain Valley CA, Spokane WA, Farmington Hills MI,
Sponsor: Hillhurst Biopharmaceuticals, Inc.
Sex: All
Age: 40 - 70+
Code: NCT07005180
Phase 2, Recruiting
A Study to Investigate Abdominal Symptoms With Camlipixant Compared With Placebo in Adults With Irritable Bowel Syndrome - Diarrhea (IBS-D) and Irritable Bowel Syndrome - Mixed (IBS-M)
for
Irritable Bowel Syndrome
Location: Anaheim CA, Garden Grove CA, Los Angeles CA,
Sponsor: GlaxoSmithKline
Sex: All
Age: 18 - 70+
Code: NCT07519395
Phase 2, Recruiting
Global Trial in APG2575 for Patients With CLL/SLL
for
CLL/SLL
Location: Anaheim CA, Tuscon AZ, Houston TX, Kingswood TX,
Sponsor: Ascentage Pharma Group Inc.
Sex: All
Age: 18 - 70+
Code: NCT06104566
Phase 3, Recruiting
A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation
for
Non-small Cell Lung Cancer,
Location: Newport Beach CA, Duarte CA, Los Angeles CA,
Sponsor: AstraZeneca
Sex: All
Age: 18+
Code: NCT05877599
Phase 1, Recruiting
VALOR: Vaginal Atrophy & Long-term Observation of Recovery
for
Atrophic Vaginitis, Vaginal Atrophy,
Location: Newport Beach CA, Burbank CA, Dallas TX, Birmingham AL,
Sponsor: Stratpharma AG
Sex: Female
Age: 18+
Code: NCT05953090
Recruiting
Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids
for
Asthma
Location: Newport Beach CA, Long Beach CA, Bakersfield CA,
Sponsor: AstraZeneca
Sex: All
Age: 18 - 70+
Code: NCT06932263
Phase 2, Recruiting
A Phase IIb Study to Evaluate AZD8965 in Participants With IPF.
for
Idiopathic Pulmonary Fibrosis (IPF)
Location: Newport Beach CA, Phoenix AZ, El Paso TX, Boise ID,
Sponsor: AstraZeneca
Sex: All
Age: 40+
Code: NCT07652658
Phase 2, Recruiting
A Study of Efficacy and Safety of Depemokimab Compared With Placebo in Adults and Adolescents With at Risk Type 2 Asthma
for
Asthma
Location: Newport Beach CA, Aurora CO, Rapid City SD,
Sponsor: GlaxoSmithKline
Sex: All
Age: 12+
Code: NCT07456033
Phase 3, Recruiting
A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kidney Injury.
for
Sepsis, Acute Kidney Injury
Location: Newport Beach CA, Kansas City KS, Detroit MI,