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Paid Clinical Trials Santa Ana

Discover 3,592 paid clinical trials in Santa Ana, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Featured

A Phase II Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib Plus Fulvestrant Versus Placebo Plus Ribociclib Plus Fulvestrant in Participants With Advanced Breast Cancer

for
Breast Cancer
Location: Anaheim CA, Palo Alto CA, Pierre SD, Mitchell SD,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07405801

Phase 2, Recruiting
Featured

A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

for
Non Small Cell Lung Cancer, c-MET
Location: Huntington Beach CA, Irvine CA, Duarte CA, Lancaster CA,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT04928846

Phase 3, Recruiting
Featured

A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination With Osimertinib as First-Line Treatment in Adult Participants With Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

for
Non-Squamous Non-Small Cell Lung Cancer, c-MET
Location: Newport Beach CA, Irvine CA, Duarte CA, Upland CA,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07005102

Phase 2, Phase 3, Recruiting
Featured

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for
Moderately to Severely Active Crohns Disease
Location: Newport Beach CA, Santa Clarita CA, Lancaster CA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 16 - 70+

Code: NCT06819891

Phase 3, Recruiting
Featured

A Study to Assess Safety, Tolerability, and How Single and Multiple Injections or Infusions of ABBV-313 Affects the Body of Adult Participants

for
Healthy Volunteers
Location: Anaheim CA, Grayslake IL
Sponsor: AbbVie

Sex: All

Age: 18 - 55

Code: NCT07673120

Phase 1, Recruiting

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Featured

Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis

for
Crohn's Disease, Ulcerative Colitis
Location: Anaheim CA, Los Alamitos CA, Rialto CA, Lancaster CA,
Sponsor: AbbVie

Sex: All

Age: 18 - 70+

Code: NCT07697456

Phase 2, Recruiting
Featured

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer

for
Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer,
Location: Irvine CA, Santa Monica CA, Duarte CA, Stanford CA,
Sponsor: Hoffmann-La Roche

Sex: Female

Age: 18+

Code: NCT04802759

Phase 1, Phase 2, Recruiting
Featured

A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer

for
Metastatic Breast Cancer
Location: Irvine CA, Corona CA, Duarte CA, Burbank CA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT05894239

Phase 3, Recruiting
Featured

A Study to Assess Adverse Events, Change in Disease Activity and How Intravenous (IV) ABBV901 Moves Through the Body Alone or in Combination With Other Anticancer Drugs in Adult Participants With Ovarian Cancer

for
Ovarian Cancer
Location: Irvine CA, Duarte CA, West Valley City UT, Denver CO,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07278336

Phase 1, Recruiting
Featured

A Study to Assess Adverse Events and Change in Disease Activity of Intravenous (IV) Telisotuzumab Adizutecan, Monotherapy or in Combination With Osimertinib, Compared to Standard of Care in Adult Participants With Locally Advanced or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer, c-MET
Location: Irvine CA, Duarte CA, La Jolla CA, Vancouver WA,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07155187

Phase 2, Phase 3, Recruiting
Featured

A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer

for
Small Cell Lung Cancer
Location: Irvine CA, Duarte CA, Goodyear AZ, Eugene OR,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07365241

Phase 3, Recruiting
Featured

Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple Myeloma

for
Multiple Myeloma
Location: Irvine CA, Duarte CA, Houston TX, Cincinnati OH,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07555938

Phase 3, Recruiting
Featured

A Study to Evaluate Adverse Events, Change in Disease Activity, Tolerability, and How Intravenous ABBV-438 Moves Through the Body in Adult Participants With Multiple Myeloma (MM)

for
Multiple Myeloma
Location: Irvine CA, Duarte CA, Denver CO, Chicago IL,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07409246

Phase 1, Recruiting
Featured

A Study to Assess the Adverse Events, Change in Disease Activity, and How Oral ABBV-711 Tablets Move Through the Body as a Monotherapy and in Combination With Intravenously Infused Budigalimab (ABBV-181), in Adults With Advanced Squamous Tumors

for
Advanced Squamous Tumors
Location: Irvine CA, Duarte CA, Irving TX, Chicago IL,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07241039

Phase 1, Recruiting
Featured

A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma Receiving T Cell Engaging Bi/Tri-specific Antibodies Intravenously (IV)/Subcutaneously (SC) Alone or in Combinations

for
Multiple Myeloma
Location: Irvine CA, Duarte CA, San Francisco CA,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06892522

Phase 1, Phase 2, Recruiting
Featured

A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer

for
Breast Cancer
Location: Irvine CA, Duarte CA, La Jolla CA, San Diego CA,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT07100106

Phase 1, Phase 2, Recruiting
Featured

A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

for
Breast Cancer
Location: Irvine CA, Los Alamitos CA, Long Beach CA, Burbank CA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06790693

Phase 3, Recruiting
Featured

Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations

for
Non Small Cell Lung Carcinoma, c-MET
Location: Fullerton CA, Santa Monica CA, Oxnard CA,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06772623

Phase 1, Phase 2, Recruiting
Featured

Evaluate Optimization of CRS Profile for Glofit Monotherapy and Glofit+GemOx in R/R Aggressive B-NHL

for
Relapsed or Refractory Aggressive B-Cell Non-Hodgkins Lymphoma
Location: Fullerton CA, Torrance CA, Glendale CA, Los Angeles CA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06806033

Phase 2, Recruiting
Featured

A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease

for
Colorectal Cancer
Location: Fullerton CA, Los Angeles CA, Portland OR,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07023289

Phase 2, Recruiting