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Paid Clinical Trials Springfield

Discover 203 paid clinical trials in Springfield, Illinois. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT05929768

Phase 3, Recruiting
Active & Responsive

Safety and Efficacy Study of ICXP007 With Compression Bandaging for the Treatment of Non-Infected Venous Leg Ulcers

for
Leg Ulcer
Location: Springfield IL, Niles IL, North Chicago IL, Columbus OH,
Sponsor: Intercytex

Sex: All

Age: 18+

Code: NCT00232973

Phase 3, Recruiting
Active & Responsive

THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension

for
Hypertension
Location: Springfield IL, Elk Grove Village IL, Kansas City MO,
Sponsor: SoniVie Inc.

Sex: All

Age: 22 - 70+

Code: NCT06559891

Recruiting
Active & Responsive

Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)

for
Obesity or Overweight
Location: Springfield IL, Skokie IL, Lenexa KS, Troy MI,
Sponsor: Amgen

Sex: All

Age: 18 - 70+

Code: NCT07575399

Phase 3, Recruiting
Active & Responsive

Deep Learning Detection of Pulmonary Hypertension and Low Ejection Fraction Via Digital Stethoscope and 3-Lead ECG

for
Hypertension, Pulmonary,
Location: Springfield IL, O'Fallon IL, Norfolk VA
Sponsor: Eko Devices, Inc.

Sex: All

Age: 18+

Code: NCT07087613

Recruiting

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Active & Responsive

Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease

for
Chronic Granulomatous Disease (CGD)
Location: Springfield IL, Jefferson City MO, Indianapolis IN,
Sponsor: Ensoma

Sex: All

Age: 0+

Code: NCT06605378

Recruiting
Active & Responsive

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

for
Advanced Endometrial Carcinoma, Recurrent Endometrial Carcinoma
Location: Springfield IL, Decatur IL, Normal IL, Peoria IL,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 18+

Code: NCT07198074

Phase 3, Recruiting
Active & Responsive

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

for
Metastatic Dedifferentiated Liposarcoma,
Location: Springfield IL, Decatur IL, Effingham IL, Mattoon IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06422806

Phase 3, Recruiting
Active & Responsive

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

for
Advanced Esophageal Adenocarcinoma,
Location: Springfield IL, Decatur IL, Effingham IL, Mattoon IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06203600

Phase 2, Phase 3, Recruiting
Active & Responsive

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

for
Clinical Stage III Cutaneous Melanoma AJCC v8,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05136196

Phase 2, Recruiting
Active & Responsive

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

for
Recurrent Head and Neck Squamous Cell Carcinoma,
Location: Springfield IL, Decatur IL, Effingham IL, Mattoon IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT04671667

Phase 2, Recruiting
Active & Responsive

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

for
Metastatic Head and Neck Squamous Cell Carcinoma,
Location: Springfield IL, Decatur IL, Normal IL, Effingham IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06589804

Phase 3, Recruiting
Active & Responsive

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

for
Colorectal Cancer Stage II, Colorectal Cancer Stage III
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT07018869

Phase 3, Recruiting
Active & Responsive

A Non-Interventional Study Observing Short-Term Progression in Geographic Atrophy (GA)

for
Geographic Atrophy Secondary to Age-related Macular Degeneration,
Location: Springfield IL, Oak Forest IL, La Crosse WI, Dallas TX,
Sponsor: Complement Therapeutics

Sex: All

Age: 55+

Code: NCT07144137

Recruiting
Active & Responsive

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

for
Plasma Cell Myeloma
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 0+

Code: NCT05561387

Phase 3, Recruiting
Active & Responsive

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

for
Ampulla of Vater Carcinoma, Appendix Carcinoma,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT07283939

Recruiting
Active & Responsive

Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

for
Miscellaneous Neoplasm, Nos, Non-Neoplastic Condition, Nos
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT07091617

Recruiting
Active & Responsive

A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)

for
Macular Degeneration, Age-Related Macular Degeneration,
Location: Springfield IL, Oak Park IL, Carmel IN, Cincinnati OH,
Sponsor: EyeBiotech Ltd.

Sex: All

Age: 50+

Code: NCT07440225

Phase 2, Phase 3, Recruiting
Active & Responsive

Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening

for
Lung Cancer Diagnosis
Location: Springfield IL, Chicago IL, Deerfield IL, Milwaukee WI,
Sponsor: Freenome Holdings Inc.

Sex: All

Age: 50+

Code: NCT06122077

Recruiting
Active & Responsive

Global Paradise System US Post Approval Study

for
Hypertension, Cardiovascular Diseases, Vascular Diseases
Location: Springfield IL, Kansas City MO, Nashville TN,
Sponsor: ReCor Medical, Inc.

Sex: All

Age: 18+

Code: NCT06297291

Recruiting