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Paid Clinical Trials Springfield

Discover 197 paid clinical trials in Springfield, Illinois. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Featured

A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

for
Breast Cancer
Location: Springfield IL, Urbana IL, O'Fallon IL, Zion IL,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06790693

Phase3, Recruiting
Featured

A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)

for
Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer,
Location: Springfield IL, Park Ridge IL, Milwaukee WI,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06065748

Phase3, Recruiting
Active & Responsive

Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT05929768

Phase3, Recruiting
Active & Responsive

Safety and Efficacy Study of ICXP007 With Compression Bandaging for the Treatment of Non-Infected Venous Leg Ulcers

for
Leg Ulcer
Location: Springfield IL, Niles IL, North Chicago IL, Columbus OH,
Sponsor: Intercytex

Sex: All

Age: 18+

Code: NCT00232973

Phase3, Recruiting
Active & Responsive

THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension

for
Hypertension
Location: Springfield IL, Elk Grove Village IL, Kansas City MO,
Sponsor: SoniVie Inc.

Sex: All

Age: 22 - 70+

Code: NCT06559891

Recruiting

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Active & Responsive

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

for
Atherosclerotic Cardiovascular Disease, Overweight, Obesity
Location: Springfield IL, St Louis MO, City of Saint Peters MO,
Sponsor: Amgen

Sex: All

Age: 45 - 70+

Code: NCT07037433

Phase3, Recruiting
Active & Responsive

Deep Learning Detection of Pulmonary Hypertension and Low Ejection Fraction Via Digital Stethoscope and 3-Lead ECG

for
Hypertension, Pulmonary,
Location: Springfield IL, O'Fallon IL, Norfolk VA
Sponsor: Eko Devices, Inc.

Sex: All

Age: 18+

Code: NCT07087613

Recruiting
Active & Responsive

Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease

for
Chronic Granulomatous Disease (CGD)
Location: Springfield IL, Jefferson City MO, Indianapolis IN,
Sponsor: Ensoma

Sex: All

Age: 0+

Code: NCT06605378

Recruiting
Active & Responsive

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

for
Metastatic Dedifferentiated Liposarcoma,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06422806

Phase3, Recruiting
Active & Responsive

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

for
Clinical Stage III Cutaneous Melanoma AJCC v8,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05136196

Phase2, Recruiting