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Paid Clinical Trials Springfield

Discover 225 paid clinical trials in Springfield, Illinois. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & ResponsiveNew

Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

for
Miscellaneous Neoplasm, Nos, Non-Neoplastic Condition, Nos
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT07091617

Recruiting
Active & Responsive

Esprit BTK Post-Approval Study

for
Chronic Limb-Threatening Ischemia
Location: Springfield IL, Indianapolis IN, Cincinnati OH,
Sponsor: Abbott Medical Devices

Sex: All

Age: 18+

Code: NCT06656364

Recruiting
Active & Responsive

Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening

for
Lung Cancer Diagnosis
Location: Springfield IL, Chicago IL, Deerfield IL, Milwaukee WI,
Sponsor: Freenome Holdings Inc.

Sex: All

Age: 50+

Code: NCT06122077

Recruiting
Active & Responsive

Deep Learning Detection of Pulmonary Hypertension and Low Ejection Fraction Via Digital Stethoscope and 3-Lead ECG

for
Hypertension, Pulmonary,
Location: Springfield IL, O'Fallon IL
Sponsor: Eko Devices, Inc.

Sex: All

Age: 18+

Code: NCT07087613

Recruiting
Active & Responsive

Real-world Experience of Catheter Ablation for the Treatment of Paroxysmal and Persistent Atrial Fibrillation

for
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
Location: Springfield IL, Columbia MO, Iowa City IA,
Sponsor: Heart Rhythm Clinical and Research Solutions, LLC

Sex: All

Age: 18+

Code: NCT04088071

Recruiting

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Active & Responsive

A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

for
Breast Cancer
Location: Springfield IL, Urbana IL, O'Fallon IL, Louisville KY,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06790693

Phase3, Recruiting
Active & Responsive

Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone Targeted Treatment for RAS Pathway Mutant Recurrent or Persistent Ovarian and Endometrial Cancers, A ComboMATCH Treatment Trial

for
Recurrent Endometrial Carcinoma,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 18+

Code: NCT05554328

Phase2, Recruiting
Active & Responsive

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

for
Biochemically Recurrent Prostate Carcinoma,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: ECOG-ACRIN Cancer Research Group

Sex: Male

Age: 18+

Code: NCT04423211

Phase3, Recruiting
Active & Responsive

Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease

for
Chronic Granulomatous Disease (CGD)
Location: Springfield IL, Jefferson City MO, Indianapolis IN,
Sponsor: Ensoma

Sex: All

Age: 0+

Code: NCT06605378

Recruiting
Active & Responsive

A Study to Investigate Safety and Tolerability of TransCon IL-2 β/γ Alone or in Combination With Pembrolizumab and/or TransCon TLR7/8 Agonist or Other Anticancer Therapies in Adult Participants With Locally Advanced or Metastatic Solid Tumor Malignancies

for
Advanced Solid Tumor, Locally Advanced Solid Tumor,
Location: Springfield IL, Louisville KY, Cincinnati OH,
Sponsor: Ascendis Pharma Oncology Division A/S

Sex: All

Age: 18+

Code: NCT05081609

Phase1, Phase2, Recruiting