Paid Clinical Trials Lexington

Discover 455 paid clinical trials in Lexington, Kentucky. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Results: 455

Upadacitinib vs. AdalimumabStudy to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib Compared to Subcutaneous Adalimumab in Adult Participants With Moderate to Severe Rheumatoid Arthritis

Recruiting

PHASE3

Sponsor:

AbbVie

Location:

Lexington KY, Evansville IN, Hopkinsville KY, Middleburg Heights OHshow 77 more

Code:

NCT05814627

Conditions

Rheumatoid Arthritis

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Upadacitinib

Adalimumab

Upadacitinib Matching Placebo

Adalimumab Matching Placebo

FrexalimabEfficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis

Recruiting

PHASE3

Sponsor:

Sanofi

Location:

Lexington KY, Louisville KY, Cincinnati OH, Centerville OHshow 80 more

Code:

NCT06141473

Conditions

Multiple Sclerosis

Eligibility Criteria

Sex: All

Age: 18 - 55

Healthy Volunteers: Not accepted

Interventions

Frexalimab

Teriflunomide

Placebo infusion

Placebo tablet

MRI contrast-enhancing agents

Neratinib & PalbociclibTesting the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

Recruiting

PHASE2

Sponsor:

National Cancer Institute (NCI)

Location:

Lexington KY, Franklin OH, Centerville OH, Kettering OHshow 111 more

Code:

NCT06126276

Conditions

Malignant Female Reproductive System Neoplasm

Malignant Solid Neoplasm

Recurrent Malignant Female Reproductive System Neoplasm

Recurrent Malignant Solid Neoplasm

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Biopsy Procedure

Biospecimen Collection

Computed Tomography

Echocardiography Test

Magnetic Resonance Imaging

SelfWrapSAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study

Recruiting

Sponsor:

VenoStent

Location:

Lexington KY, Fort Wayne IN, Greenville SC, Spartanburg SCshow 17 more

Code:

NCT06001827

Conditions

Chronic Kidney Diseases

End Stage Renal Disease

Arteriovenous Fistula

Hemodialysis Access Failure

ESRD

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

SelfWrap Bioabsorbable Perivascular Wrap

Untreated AVF Control

177Lu-DOTATATE vs. EverolimusComparing Retreatment of 177Lu-DOTATATE PRRT Versus Everolimus in Patients With Metastatic Unresectable Midgut Neuroendocrine Tumors, NET RETREAT Trial

Recruiting

PHASE2

Sponsor:

National Cancer Institute (NCI)

Location:

Lexington KY, Columbus OH, New Lenox IL, Orland Park ILshow 22 more

Code:

NCT05773274

Conditions

Metastatic Midgut Neuroendocrine Tumor

Metastatic Midgut Neuroendocrine Tumor G1

Metastatic Midgut Neuroendocrine Tumor G2

Unresectable Midgut Neuroendocrine Tumor

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Biospecimen Collection

Computed Tomography

Everolimus

Lutetium Lu 177 Dotatate

Quality-of-Life Assessment

Observational StudyNeurobehavioral Mechanisms of Choice in Opioid Use Disorder

Recruiting

EARLY_PHASE1

Sponsor:

Joshua A. Lile, Ph.D.

Location:

Lexington KY

Code:

NCT03958474

Conditions

Opioid Use Disorder

Eligibility Criteria

Sex: All

Age: 18 - 50

Healthy Volunteers: Not accepted

Interventions

Oxycodone

Remifentanil

Amivantamab-SubcutaneousTargeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

Recruiting

PHASE2

Sponsor:

SWOG Cancer Research Network

Location:

Lexington KY, Huntington WV, Danville IL, Effingham ILshow 85 more

Code:

NCT06116682

Conditions

Lung Non-Small Cell Carcinoma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Amivantamab

Biospecimen Collection

Computed Tomography

Magnetic Resonance Imaging

Nivolumab, Ipilimumab, CabozantinibTesting the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

Recruiting

PHASE2

Sponsor:

National Cancer Institute (NCI)

Location:

Lexington KY, Bardstown KY, Shepherdsville KY, London KYshow 368 more

Code:

NCT03866382

Conditions

Bladder Adenocarcinoma

Bladder Clear Cell Adenocarcinoma

Bladder Mixed Adenocarcinoma

Bladder Neuroendocrine Carcinoma

Bladder Small Cell Neuroendocrine Carcinoma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Biospecimen Collection

Bone Scan

Cabozantinib S-malate

Computed Tomography

Echocardiography Test

AvacopanA Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis

Recruiting

Sponsor:

Amgen

Location:

Lexington KY, New Albany IN, Miamisburg OH, Columbus OHshow 33 more

Code:

NCT06072482

Conditions

Antineutrophil Cytoplasmic Antibody-associated Vasculitis

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Avacopan

Placebo

Standard of Care

LMN-201LMN-201 for Prevention of C. Difficile Infection Recurrence

Recruiting

PHASE2

PHASE3

Sponsor:

Lumen Bioscience, Inc.

Location:

Lexington KY, Mount Airy NC, Decatur GA, Willoughby OHshow 13 more

Code:

NCT05330182

Conditions

Clostridioides Difficile Infection

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

LMN-201

Placebo