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Paid Clinical Trials Louisville

Discover 495 paid clinical trials in Louisville, Kentucky. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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FeaturedActive & Responsive

A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for
Moderately to Severely Active Crohns Disease
Location: Louisville KY, New Albany IN, Crestview Hills KY,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 16 - 70+

Code: NCT06819878

Phase3, Recruiting
FeaturedActive & Responsive

A Surveillance Study of Susceptibility to Baloxavir Marboxil in Pediatric Participants With Influenza and Transmission of Influenza to Household Contacts

for
Influenza
Location: Bardstown KY, Mishawaka IN, Middleburg Heights OH,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 0 - 11

Code: NCT06094010

Phase3, Recruiting
Featured

A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

for
Breast Cancer
Location: Louisville KY, Lexington KY, Nashville TN, Urbana IL,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06790693

Phase3, Recruiting
Featured

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for
Moderately to Severely Active Crohns Disease
Location: Louisville KY, Beavercreek OH, Nashville TN,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 16 - 70+

Code: NCT06819891

Phase3, Recruiting
Featured

Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities

for
Obesity, Overweight
Location: Louisville KY, Cincinnati OH, Nashville TN,
Sponsor: AbbVie

Sex: All

Age: 18 - 70+

Code: NCT07752979

Phase2, Recruiting

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Featured

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

for
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis,
Location: New Albany IN, Louisville KY, Liberty Township OH,
Sponsor: 89bio, Inc.

Sex: All

Age: 18 - 70+

Code: NCT06318169

Phase3, Recruiting
Featured

A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

for
Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis,
Location: New Albany IN, Louisville KY, Cincinnati OH,
Sponsor: 89bio, Inc.

Sex: All

Age: 18 - 70+

Code: NCT06419374

Phase3, Recruiting
Featured

Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis

for
Crohn's Disease, Ulcerative Colitis
Location: Louisville KY, New Albany IN, Knoxville TN, St Louis MO,
Sponsor: AbbVie

Sex: All

Age: 18 - 70+

Code: NCT07697456

Phase2, Recruiting
Featured

A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer

for
Small Cell Lung Cancer
Location: Louisville KY, Indianapolis IN, Fairfield OH,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07365241

Phase3, Recruiting
Featured

A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.

for
Epithelial Ovarian Cancer, Fallopian Tube Cancer,
Location: Louisville KY, Lexington KY, Indianapolis IN,
Sponsor: AbbVie

Sex: Female

Age: 18+

Code: NCT06890338

Phase2, Recruiting
Active & Responsive

Harm Reduction for Smokers With Mental Illness

for
Tobacco Dependence
Location: Louisville KY, Providence RI
Sponsor: Dartmouth-Hitchcock Medical Center

Sex: All

Age: 21+

Code: NCT06543407

Recruiting
Active & Responsive

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

for
NASH - Nonalcoholic Steatohepatitis,
Location: Louisville KY, Indianapolis IN, Springboro OH,
Sponsor: Akero Therapeutics, Inc

Sex: All

Age: 18 - 70+

Code: NCT06528314

Phase3, Recruiting
Active & Responsive

A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis

for
NASH With Fibrosis, MASH With Fibrosis
Location: Louisville KY, Indianapolis IN, Springboro OH,
Sponsor: Akero Therapeutics, Inc

Sex: All

Age: 18 - 70+

Code: NCT06215716

Phase3, Recruiting
Active & Responsive

FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

for
Metastatic Head and Neck Squamous Cell Carcinoma,
Location: Louisville KY, Lexington KY, Cincinnati OH,
Sponsor: Bicara Therapeutics

Sex: All

Age: 18+

Code: NCT06788990

Phase2, Phase3, Recruiting
Active & Responsive

Aptis PRUJ Prosthesis for the Treatment of Patients With Proximal Radial Ulna Joint Disorders.

for
Arthritis, Unstable Radial Head,
Location: Louisville KY, Carmel IN, Dayton OH, Milwaukee WI,
Sponsor: Aptis Medical

Sex: All

Age: 18 - 70+

Code: NCT05796908

Recruiting
Active & Responsive

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)

for
Sickle Cell Disease
Location: Louisville KY, Chicago IL, Riverdale GA, Birmingham AL,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 12 - 70+

Code: NCT06439082

Phase3, Recruiting
Active & Responsive

Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

for
Acute Myeloid Leukemia
Location: Louisville KY, Indianapolis IN, Nashville TN,
Sponsor: PedAL BCU, LLC

Sex: All

Age: 0 - 21

Code: NCT05183035

Phase3, Recruiting
Active & Responsive

Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

for
Pleuropulmonary Blastoma
Location: Louisville KY, Cincinnati OH, Indianapolis IN,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 21

Code: NCT06647953

Phase3, Recruiting
Active & Responsive

AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

for
Obesity, Overweight, Osteoarthritis, Knee
Location: Louisville KY, Skokie IL, Gurnee IL, Statesville NC,
Sponsor: Novo Nordisk A/S

Sex: All

Age: 18+

Code: NCT07509307

Phase3, Recruiting
Active & Responsive

A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to Moderate Lumbar Degenerative Disc Disease

for
Degenerative Disc Disease
Location: Louisville KY, Carmel IN, St Louis MO, Memphis TN,
Sponsor: DiscGenics, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07254806

Phase3, Recruiting