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Paid Clinical Trials Worcester

Discover 3,097 paid clinical trials in Worcester, Massachusetts. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & ResponsiveNew

Outcomes of Neurosurgical Tone Management

for
Spastic/Dystonic Quadriplegia, Cerebral Palsy (CP)
Location: Boston MA
Sponsor: Boston Children's Hospital

Sex: All

Age: 6 - 25

Code: NCT07817745

Recruiting
Active & ResponsiveNew

Study of Cabozantinib With Selumetinib for Plexiform Neurofibromas

for
Neurofibromatosis 1, Plexiform Neurofibroma
Location: Boston MA, Philadelphia PA, Washington D.C. DC,
Sponsor: Girish Dhall, MD

Sex: All

Age: 16+

Code: NCT06502171

Phase1, Recruiting
Active & Responsive

Molecular Genetic Mechanisms of Infantile Epilepsies and the Impact of Genetic Diagnosis

for
Neonatal Epilepsy, Infantile Epilepsy
Location: Boston MA
Sponsor: Boston Children's Hospital

Sex: All

Age: 0+

Code: NCT06701084

Recruiting
Active & Responsive

A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants, Adolescents and Adults With Hearing Loss Due to Otoferlin Mutations

for
Congenital Hearing Loss Secondary to Biallelic Mutations of the Otoferlin Gene (OTOF),
Location: Boston MA, New York NY, Cincinnati OH, Milwaukee WI,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 0+

Code: NCT05788536

Phase1, Phase2, Recruiting
Active & Responsive

Advancing Transplantation Outcomes in Children

for
Kidney Transplant
Location: Boston MA, Philadelphia PA, Wilmington DE, Baltimore MD,
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 13 - 20

Code: NCT06055608

Phase2, Recruiting

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Active & Responsive

Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia

for
Hereditary Spastic Paraplegia, SPG47, SPG50, SPG51, SPG52,
Location: Boston MA
Sponsor: Boston Children's Hospital

Sex: All

Age: 0 - 30

Code: NCT04712812

Recruiting
Active & Responsive

Allogeneic Valve Transplantation

for
Valve Heart Disease, Valve Disease, Heart,
Location: Boston MA
Sponsor: Boston Children's Hospital

Sex: All

Age: 0 - 50

Code: NCT06387446

Recruiting
Active & Responsive

Establishing Walking-related Digital Biomarkers in Rare Childhood Onset Progressive Neuromuscular Disorders

for
Spinal Muscular Atrophy Type 3,
Location: Boston MA, New York NY, Palo Alto CA
Sponsor: Columbia University

Sex: All

Age: 5+

Code: NCT06839469

Recruiting
Active & Responsive

Slow Heart Registry of Fetal Immune-mediated High Degree Heart Block

for
Heart Block Complete, Heart Block Second Degree
Location: Boston MA, New York NY, Washington DC, Toronto, Halifax,
Sponsor: The Hospital for Sick Children

Sex: Female

Age: 16 - 50

Code: NCT04559425

Recruiting
Active & Responsive

Spastic Paraplegia - Centers of Excellence Research Network

for
Hereditary Spastic Paraplegia, Primary Lateral Sclerosis, SPG4,
Location: Boston MA
Sponsor: Boston Children's Hospital

Sex: All

Age: 0+

Code: NCT06553976

Recruiting
Active & Responsive

Delineating the Molecular Spectrum and the Clinical, Imaging and Neuronal Phenotype of Chopra-Amiel-Gordon Syndrome

for
Genetic Disease, Chopra-Amiel-Gordon Syndrome, CAGS, ANKRD17
Location: Boston MA
Sponsor: Boston Children's Hospital

Sex: All

Age: 0+

Code: NCT05528744

Recruiting
Active & Responsive

A First-in-human Study of S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic Encephalopathy

for
Epileptic Encephalopathy
Location: Boston MA
Sponsor: Institut de Recherches Internationales Servier

Sex: All

Age: 2 - 12

Code: NCT07227857

Phase1, Phase2, Recruiting
Active & Responsive

Phase 2 Study to Assess the Safety and Efficacy of ANG003

for
Exocrine Pancreatic Insufficiency (EPI), Cystic Fibrosis (CF)
Location: Boston MA, New Brunswick NJ, Hershey PA, Akron OH,
Sponsor: Anagram Therapeutics, Inc.

Sex: All

Age: 12+

Code: NCT07450547

Phase2, Recruiting
Active & Responsive

A Pragmatic Clinical Trial of the WE BEAT Well-Being Education Program in Adolescent Congenital Heart Disease: WE BEAT CHD Study

for
Patient-Reported Outcome Measures (PROMs), Pragmatic Trial,
Location: Boston MA, New York NY, Philadelphia PA, Pittsburgh PA,
Sponsor: Carelon Research

Sex: All

Age: 12 - 17

Code: NCT07525843

Recruiting
Active & Responsive

A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy

for
Spinal Muscular Atrophy (SMA)
Location: Boston MA, Hartford CT, Hillsborough NC, Chicago IL,
Sponsor: argenx

Sex: All

Age: 5 - 17

Code: NCT07287982

Phase2, Recruiting
Active & Responsive

Prevention of Bleeding in Patients With Moderate and Severe Hemophilia A Playing Sports: A Comparison Between Factor VIII and Emicizumab Prophylaxis

for
Hemophilia A
Location: Boston MA, Detroit MI, Cincinnati OH, Indianapolis IN,
Sponsor: Wayne State University

Sex: All

Age: 6 - 19

Code: NCT05022459

Recruiting
Active & Responsive

A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH)

for
Congenital Adrenal Hyperplasia,
Location: Boston MA, New York NY, New Brunswick NJ,
Sponsor: Crinetics Pharmaceuticals Inc.

Sex: All

Age: 1 - 17

Code: NCT07159841

Phase2, Phase3, Recruiting
Active & Responsive

Restarting Triple Therapy With Robust Monitoring for Adverse Events (RETRIAL)

for
Cystic Fibrosis
Location: Boston MA, Wilmington DE, Baltimore MD, Pittsburgh PA,
Sponsor: Boston Children's Hospital

Sex: All

Age: 6+

Code: NCT06683092

Recruiting
Active & Responsive

Breaking Silence Through Story: A Narrative Medicine Intervention for Parents of Children With Urogenital Conditions

for
DSD, Hypospadias
Location: Boston MA
Sponsor: Sarah Schlegel

Sex: All

Age: 18+

Code: NCT06989593

Recruiting
Active & Responsive

Valproate for the Treatment of Residual Amblyopia

for
Amblyopia, Amblyopia Unilateral, Amblyopia, Anisometropic,
Location: Boston MA
Sponsor: Boston Children's Hospital

Sex: All

Age: 8 - 17

Code: NCT07226141

Phase1, Phase2, Recruiting