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Paid Clinical Trials Worcester

Discover 3,097 paid clinical trials in Worcester, Massachusetts. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR

for
Aortic Stenosis, Calcific, Aortic Valve Stenosis
Location: Boston MA, New Haven CT, Lebanon NH, Roslyn NY,
Sponsor: Edwards Lifesciences

Sex: All

Age: 65+

Code: NCT04889872

Recruiting

Auryon Atherectomy System With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone

for
Peripheral Arterial Diseases
Location: Boston MA, Baltimore MD, Cleveland OH, Chapel Hill NC,
Sponsor: Angiodynamics, Inc.

Sex: All

Age: 0+

Code: NCT06777901

Recruiting

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

for
Non-small Cell Lung Cancer (NSCLC), Colorectal Cancer (CRC),
Location: Boston MA, New Haven CT, New York NY, Baltimore MD,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT06040541

Phase1, Recruiting

High-Intensity Interval Exercise in Young Adult Survivors of Pediatric Brain Tumors: A Pilot Feasibility Study

for
Pediatric Brain Tumor
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18 - 45

Code: NCT05740839

Recruiting

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

for
Breast Cancer, Solid Tumors, Adult
Location: Boston MA, New York NY, Fairfax VA, Cleveland OH,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT05768139

Phase1, Phase2, Recruiting

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Intermittent Theta Burst Stimulation (iTBS) for Emotion Regulation in Bipolar Disorder

for
Bipolar Disorder
Location: Charlestown MA, Philadelphia PA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 24 - 65

Code: NCT06274567

Recruiting

Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement

for
Aortic Stenosis, Coronary Artery Disease, Coronary Stenosis
Location: Providence RI, Boston MA, Lebanon NH, Mineola NY,
Sponsor: University of British Columbia

Sex: All

Age: 0+

Code: NCT04634240

Recruiting

Serial MRI Scans During Radiation Therapy

for
Glioblastoma, Esophageal Cancer, Radiotherapy,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT04188535

Recruiting

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

for
Endometrial Cancer
Location: Boston MA, Providence RI, Lebanon NH, Hackensack NJ,
Sponsor: AstraZeneca

Sex: Female

Age: 18+

Code: NCT06989112

Phase3, Recruiting

Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib

for
Myelofibrosis, Post-PV MF, Post-ET Myelofibrosis,
Location: Boston MA, Lake Success NY, The Bronx NY, Hackensack NJ,
Sponsor: Kartos Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06479135

Phase3, Recruiting

Paxalisib (GDC-0084) In Recurrent Or Refractory PCNSL

for
Primary Central Nervous System Lymphoma,
Location: Boston MA
Sponsor: Lakshmi Nayak, MD

Sex: All

Age: 18+

Code: NCT04906096

Phase2, Recruiting

This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.

for
Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung,
Location: Fall River MA, Fairhaven MA, Scarborough ME,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT06758401

Phase3, Recruiting

Onyx™ Liquid Embolic IDE Clinical Study

for
Peripheral Arterial Hemorrhage, Trauma, GI Bleed, Ulcer,
Location: Boston MA, New Haven CT, Albany NY, New York NY,
Sponsor: Medtronic Endovascular

Sex: All

Age: 22+

Code: NCT06742801

Recruiting

A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

for
Myelodysplastic Syndromes, Acute Myeloid Leukemia,
Location: Boston MA, New Haven CT, Mineola NY, The Bronx NY,
Sponsor: Taiho Oncology, Inc.

Sex: All

Age: 18+

Code: NCT04256317

Phase2, Phase3, Recruiting

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

for
Metastatic Malignant Neoplasm in the Lung,
Location: Boston MA, Providence RI, Hartford CT, New Haven CT,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 50

Code: NCT05235165

Phase3, Recruiting

A Mobile App-Based Study to Evaluate Disease Burden and Treatment Patterns in Immunoglobulin A Nephropathy (IgAN) in the US

for
Immunoglobulin A Nephropathy
Location: Boston MA
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06952426

Recruiting

IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301)

for
Advanced Melanoma
Location: Boston MA, Lake Success NY, Hackensack NJ,
Sponsor: Immunocore Ltd

Sex: All

Age: 18+

Code: NCT06112314

Phase3, Recruiting

Surveillance vs. Endoscopic Therapy for Barrett's Esophagus With Low-grade Dysplasia

for
Barretts Esophagus With Dysplasia, Barrett Esophagus,
Location: Boston MA, Lebanon NH, Manhasset NY, New York NY,
Sponsor: University of Colorado, Denver

Sex: All

Age: 18 - 70+

Code: NCT05753748

Recruiting

A Study to Assess the Efficacy and Safety of Debio 4126 in Participants With Acromegaly Previously Treated With Somatostatin Analogs

for
Acromegaly
Location: Boston MA, Philadelphia PA, Cleveland OH, Columbus OH,
Sponsor: Debiopharm International SA

Sex: All

Age: 18+

Code: NCT06930625

Phase3, Recruiting

LYL273 for Patients With Relapsed or Refractory mCRC

for
Colorectal Cancer
Location: Boston MA, Aurora CO, Duarte CA, San Francisco CA
Sponsor: Lyell Immunopharma, Inc.

Sex: All

Age: 18+

Code: NCT05319314

Phase1, Phase2, Recruiting