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Paid Clinical Trials Detroit

Discover 1,705 paid clinical trials in Detroit, Michigan. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

Mild Intermittent Hypoxia and Its Multipronged Effect on Sleep Apnea

for
Obstructive Sleep Apnea, Spinal Cord Injuries
Location: Detroit MI
Sponsor: Wayne State University

Sex: All

Age: 18 - 60

Code: NCT03736382

Recruiting
Active & Responsive

An Open-Label Extension Study of ORKA-001 in Participants With Plaque Psoriasis

for
Plaque Psoriasis
Location: Detroit MI, London, Waterloo, Toronto, Markham, Ajax,
Sponsor: Oruka Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07449702

Phase2, Recruiting
Active & Responsive

TNF-α Treatment of Blast-Induced Tinnitus

for
Tinnitus, Noise Induced
Location: Detroit MI, Farmington Hills MI, Celebration FL,
Sponsor: Wayne State University

Sex: All

Age: 18+

Code: NCT04066348

Phase2, Recruiting
Active & Responsive

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

for
Glioblastoma (GBM), Newly Diagnosed Glioblastoma, GBM,
Location: Detroit MI, Columbus OH, Pittsburgh PA, Fairfax VA,
Sponsor: Black Diamond Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07326566

Phase2, Recruiting
Active & Responsive

A Study of DM005 in Patients With Advanced Solid Tumors

for
Carcinoma, Non-Small-Cell Lung,
Location: Detroit MI, Fairfax VA, Dallas TX
Sponsor: Doma Biopharmaceutical（Suzhou）Co., Ltd.

Sex: All

Age: 18+

Code: NCT06515990

Phase1, Phase2, Recruiting

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Active & Responsive

Sacituzumab Govitecan in Combination With Capecitabine for Advanced Gastrointestinal Cancers After Progression on Standard Therapy

for
Gastrointestinal Cancer
Location: Detroit MI
Sponsor: Henry Ford Health System

Sex: All

Age: 18+

Code: NCT06065371

Phase1, Recruiting
Active & Responsive

A Study to Assess the Efficacy and Safety of RO7790121 in Participants With Moderate to Severe Rheumatoid Arthritis Who Have Not Responded to or Who Cannot Tolerate Tumor Necrosis Factor (TNF) and/or Janus Kinase (JAK Inhibitors)

for
Rheumatoid Arthritis
Location: Detroit MI, Columbus OH, Glendale WI, Willowbrook IL,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07137598

Phase2, Recruiting
Active & Responsive

Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD

for
COPD, Chronic Obstructive Pulmonary Disease
Location: Detroit MI, Columbus OH, DuBois PA, Philadelphia PA,
Sponsor: Nuvaira, Inc.

Sex: All

Age: 40 - 70+

Code: NCT07051707

Recruiting
Active & Responsive

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

for
Breast Neoplasms
Location: Detroit MI, Toronto, Chicago IL, Edgewood KY,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06312176

Phase3, Recruiting
Active & Responsive

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

for
Metastatic Dedifferentiated Liposarcoma,
Location: Detroit MI, Dearborn MI, Wyandotte MI, Brownstown MI,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06422806

Phase3, Recruiting
Active & Responsive

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

for
Diabetes Mellitus, Type 2, PreDiabetes, Metabolic Syndrome
Location: Detroit MI, Ypsilanti MI, Akron OH, Chicago IL,
Sponsor: Cleerly, Inc.

Sex: All

Age: 55+

Code: NCT06112418

Recruiting
Active & Responsive

HEART Camp Connect -Promoting Exercise in Adults With Heart Failure With Preserved Ejection Fraction

for
HFpEF - Heart Failure With Preserved Ejection Fraction
Location: Detroit MI, Omaha NE
Sponsor: University of Nebraska

Sex: All

Age: 18+

Code: NCT05784753

Recruiting
Active & Responsive

Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial

for
Surgery-Complications, Anesthesia Complication,
Location: Detroit MI, Ann Arbor MI, Charlottesville VA,
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT05991453

Recruiting
Active & Responsive

Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)

for
Brain Tumor, Recurrent, Brain Tumor, Brain Tumor, Primary,
Location: Detroit MI, Kettering OH, Pittsburgh PA, Carmel IN,
Sponsor: GT Medical Technologies, Inc.

Sex: All

Age: 0+

Code: NCT04427384

Recruiting
Active & Responsive

ASSESS ALL ALS Study

for
Amyotrophic Lateral Sclerosis
Location: Detroit MI, Ann Arbor MI, Colombus OH, Chicago IL,
Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All

Age: 18+

Code: NCT06578195

Recruiting
Active & Responsive

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

for
Cardiovascular Disease
Location: Detroit MI, Southfield MI, Rochester Hills MI, London,
Sponsor: Amgen

Sex: All

Age: 50 - 70+

Code: NCT07136012

Phase3, Recruiting
Active & Responsive

A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062)

for
Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Location: Detroit MI, Columbus OH, Chicago IL, Washington D.C. DC,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07266831

Phase2, Phase3, Recruiting
Active & Responsive

ALS/MND Natural History Study Data Repository

for
ALS, PLS, MND (Motor Neurone DIsease), Kennedy Disease,
Location: Detroit MI, Grand Rapids MI, Pittsburgh PA, Chicago IL,
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18 - 70+

Code: NCT05966038

Recruiting
Active & Responsive

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

for
Heart Failure With Preserved Ejection Fraction,
Location: Detroit MI, Rochester Hills MI, Ann Arbor MI, Sarnia,
Sponsor: Amgen

Sex: All

Age: 18 - 70+

Code: NCT07037459

Phase3, Recruiting
Active & Responsive

Promote Weight Loss in Obese Peripheral Artery Disease (PAD) Patients to Prevent Mobility Loss

for
Peripheral Artery Disease, Overweight or Obesity
Location: Detroit MI, Columbus OH, Chicago IL, Baltimore MD,
Sponsor: Northwestern University

Sex: All

Age: 18+

Code: NCT04228978

Recruiting