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Paid Clinical Trials Detroit

Discover 1,725 paid clinical trials in Detroit, Michigan. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

A First-In-Human, Phase 1 Study Evaluating Oral TACC3 PPI Inhibitor, AO-252, in Advanced Solid Tumors With or Without Brain Metastases

for
Solid Tumor Malignancies, Brain Metastases From Solid Tumors
Location: Detroit MI, Fairfax VA, Charleston SC, Oklahoma City OK,
Sponsor: A2A Pharmaceuticals Inc.

Sex: All

Age: 18+

Code: NCT06136884

Phase 1, Recruiting
Active & Responsive

A Phase 1 Study to Evaluate Safety and Efficacy of XER-001 (Amifostine for Nasoduodenal Delivery) in Combination With Sterotactic Body Radiotherapy for Treatment in Patients With Locally Advanced Pancreatic Cancer.

for
Locally Advanced Pancreatic Adenocarcinoma,
Location: Detroit MI, Houston TX, Santa Fe NM, Duarte CA,
Sponsor: Xerient Pharma

Sex: All

Age: 18+

Code: NCT07157033

Phase 1, Phase 2, Recruiting
Active & Responsive

A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma

for
Multiple Myeloma, Relapsed/Refractory Multiple Myeloma
Location: Detroit MI, Ann Arbor MI, Grand Rapids MI,
Sponsor: C4 Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07284758

Phase 2, Recruiting
Active & Responsive

A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known to Express the Tumor Marker CA19-9

for
Advanced Solid Cancers
Location: Detroit MI, New York NY, Orlando FL, Denver CO
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT07186842

Phase 1, Phase 2, Recruiting
Active & Responsive

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

for
Breast Neoplasms, Colorectal Neoplasms, Prostate Neoplasm,
Location: Detroit MI, Grand Rapids MI, Hamilton, Toronto,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07114601

Phase 1, Recruiting

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Active & Responsive

A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

for
Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer,
Location: Detroit MI, Ann Arbor MI, Pittsburgh PA, Chicago IL,
Sponsor: Astellas Pharma Global Development, Inc.

Sex: All

Age: 18+

Code: NCT06901531

Phase 3, Recruiting
Active & Responsive

RENAISSANCE 2: SPN-817 Phase 2, Double-Blind, Placebo-Controlled Study in Adults With Focal Onset Seizures

for
Focal Onset Seizures
Location: Detroit MI, Cleveland OH, Amherst NY, Rochester NY,
Sponsor: Supernus Pharmaceuticals, Inc.

Sex: All

Age: 18 - 70

Code: NCT06798896

Phase 2, Recruiting
Active & Responsive

Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))

for
Mesial Temporal Lobe Epilepsy
Location: Detroit MI, Buffalo NY, Chicago IL, Milwaukee WI,
Sponsor: Neurona Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT05135091

Phase 3, Recruiting
Active & Responsive

A Long-term Safety and Efficacy Study Evaluating APG777 in Atopic Dermatitis

for
Atopic Dermatitis
Location: Detroit MI, Troy MI, Boardman OH, Mississauga,
Sponsor: Apogee Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07003425

Phase 2, Recruiting
Active & Responsive

Clarifying the Optimal Application of SLT Therapy Trial

for
Glaucoma and Ocular Hypertension
Location: Detroit MI, Ann Arbor MI, Cleveland OH, Chicago IL,
Sponsor: University of Pittsburgh

Sex: All

Age: 18+

Code: NCT04967989

Phase 3, Recruiting
Active & Responsive

An Open-Label Extension Study of ORKA-001 in Participants With Plaque Psoriasis

for
Plaque Psoriasis
Location: Detroit MI, Cleveland OH, London, Waterloo, Toronto,
Sponsor: Oruka Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07449702

Phase 2, Recruiting
Active & Responsive

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

for
Glioblastoma (GBM), Newly Diagnosed Glioblastoma, GBM,
Location: Detroit MI, Ann Arbor MI, Cleveland OH, Columbus OH,
Sponsor: Black Diamond Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07326566

Phase 2, Recruiting
Active & Responsive

A Study of DM005 in Patients With Advanced Solid Tumors

for
Carcinoma, Non-Small-Cell Lung,
Location: Detroit MI, Fairfax VA, Dallas TX
Sponsor: Doma Biopharmaceutical（Suzhou）Co., Ltd.

Sex: All

Age: 18+

Code: NCT06515990

Phase 1, Phase 2, Recruiting
Active & Responsive

Sacituzumab Govitecan in Combination With Capecitabine for Advanced Gastrointestinal Cancers After Progression on Standard Therapy

for
Gastrointestinal Cancer
Location: Detroit MI
Sponsor: Henry Ford Health System

Sex: All

Age: 18+

Code: NCT06065371

Phase 1, Recruiting
Active & Responsive

A Study to Assess the Efficacy and Safety of RO7790121 in Participants With Moderate to Severe Rheumatoid Arthritis Who Have Not Responded to or Who Cannot Tolerate Tumor Necrosis Factor (TNF) and/or Janus Kinase (JAK Inhibitors)

for
Rheumatoid Arthritis
Location: Detroit MI, Columbus OH, Glendale WI, Willowbrook IL,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07137598

Phase 2, Recruiting
Active & Responsive

Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD

for
COPD, Chronic Obstructive Pulmonary Disease
Location: Detroit MI, Columbus OH, DuBois PA, Philadelphia PA,
Sponsor: Nuvaira, Inc.

Sex: All

Age: 40 - 70+

Code: NCT07051707

Recruiting
Active & Responsive

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

for
Breast Neoplasms
Location: Detroit MI, Toronto, Chicago IL, Edgewood KY,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06312176

Phase 3, Recruiting
Active & Responsive

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

for
Metastatic Dedifferentiated Liposarcoma,
Location: Detroit MI, Dearborn MI, Wyandotte MI, Brownstown MI,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06422806

Phase 3, Recruiting
Active & Responsive

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

for
Advanced Esophageal Adenocarcinoma,
Location: Detroit MI, Dearborn MI, Wyandotte MI, Brownstown MI,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06203600

Phase 2, Phase 3, Recruiting
Active & Responsive

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

for
Diabetes Mellitus, Type 2, PreDiabetes, Metabolic Syndrome
Location: Detroit MI, Ypsilanti MI, Akron OH, Chicago IL,
Sponsor: Cleerly, Inc.

Sex: All

Age: 55+

Code: NCT06112418

Recruiting