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Paid Clinical Trials Buffalo

Discover 779 paid clinical trials in Buffalo, New York. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

for
Triple-Negative Breast Cancer
Location: Hamilton, Toronto, Kingston, Canton OH, Massillon OH,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06393374

Phase 3, Recruiting

A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease

for
Chronic Graft-versus-host-disease
Location: Hamilton, Toronto, Rochester NY, Pittsburgh PA,
Sponsor: Incyte Corporation

Sex: All

Age: 12+

Code: NCT06585774

Phase 3, Recruiting

International Registry for Men With Advanced Prostate Cancer (IRONMAN)

for
Prostate Cancer
Location: Hamilton, Toronto, Cleveland OH, Detroit MI,
Sponsor: Prostate Cancer Clinical Trials Consortium

Sex: Male

Age: 21+

Code: NCT03151629

Recruiting

A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)

for
Non-small Cell Lung Cancer
Location: Hamilton, Toronto, Lancaster PA, Albany NY, Stamford CT,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06345729

Phase 3, Recruiting

Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

for
Non-small Cell Lung Cancer (NSCLC)
Location: Hamilton, Toronto, Brampton, East Syracuse NY,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07291037

Phase 3, Recruiting

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A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma

for
Multiple Myeloma
Location: Hamilton, Toronto, London, Baltimore MD,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT07258511

Phase 3, Recruiting

A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia

for
Chronic Lymphocytic Leukemia
Location: Hamilton, Pittsburgh PA, New York NY, Montreal,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT07277231

Phase 3, Recruiting

A Study of Surovatamig (AZD0486) Plus Rituximab in Previously Untreated Follicular Lymphoma Patients

for
Untreated Follicular Lymphoma
Location: Hamilton, Toronto, Oshawa, Albany NY, Bethesda MD,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06549595

Phase 3, Recruiting

A Study of Tacabrutideg (BGB-16673) Compared to Investigator's Choice in Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Both Bruton Tyrosine Kinase (BTK) and B-cell Leukemia/Lymphoma 2 Protein (BCL2) Inhibitors

for
CLL, Chronic Lymphocytic Leukemia
Location: Hamilton, London, Cleveland OH, Pittsburgh PA, York PA,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT06846671

Phase 3, Recruiting

A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis

for
Myelofibrosis
Location: Hamilton, Toronto, Ann Arbor MI, Baltimore MD,
Sponsor: Sumitomo Pharma America, Inc.

Sex: All

Age: 18+

Code: NCT04176198

Phase 1, Phase 2, Recruiting

AZD0305 as Monotherapy or in Combination With Anticancer Agents in Participants With Multiple Myeloma

for
Multiple Myeloma
Location: Hamilton, Ottawa, Ann Arbor MI, Philadelphia PA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06106945

Phase 1, Phase 2, Recruiting

A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)

for
Diffuse Large B-Cell Lymphoma
Location: Hamilton, Toronto, Oshawa, Detroit MI, Ann Arbor MI,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06717347

Phase 3, Recruiting

A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)

for
Breast Cancer
Location: Hamilton, Toronto, Barrie, Cleveland OH, Detroit MI,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06103864

Phase 3, Recruiting

A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma

for
Neoplasms, Head and Neck
Location: Hamilton, Pittsburgh PA, Canton OH, Greater Sudbury,
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT06256588

Phase 3, Recruiting

Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable

for
Atrial Fibrillation (AF)
Location: Hamilton, Bloomfield Hills MI, Farmington Hills MI,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07430956

Phase 3, Recruiting

A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

for
Heart Failure
Location: Hamilton, Mississauga, Oakville, Oshawa, Cambridge,
Sponsor: Boehringer Ingelheim

Sex: All

Age: 18+

Code: NCT06935370

Phase 3, Recruiting

A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation

for
Atrial Fibrillation
Location: Hamilton, Toronto, Newmarket, London, Camden NJ,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07217067

Phase 2, Recruiting

A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

for
Chronic Obstructive Pulmonary Disease (COPD)
Location: Hamilton, Burlington, Ajax, Guelph, Stoney Creek,
Sponsor: AstraZeneca

Sex: All

Age: 40+

Code: NCT07082738

Phase 2, Recruiting

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

for
Heart Failure and Impaired Kidney Function
Location: Hamilton, Toronto, North York, Cambridge, Newmarket,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06307652

Phase 3, Recruiting

A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

for
COPD (Chronic Obstructive Pulmonary Disease)
Location: Hamilton, Ajax, Guelph, Kingston, Camp Hill PA,
Sponsor: AstraZeneca

Sex: All

Age: 40 - 70+

Code: NCT06283966

Phase 3, Recruiting