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A Study to Assess Adverse Events and Change in Disease Activity When Intravenous (IV) Pivekimab Sunirine is Given in Combination With Oral Venetoclax and IV or Subcutaneous Azacitidine in Adult Participants With Acute Myeloid Leukemia (AML)

for
Acute Myeloid Leukemia
Location: The Bronx NY, Tampa FL, Atlanta GA, Houston TX,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07581002

Phase2, Phase3, Recruiting
Featured

A Study to Assess Adverse Events and How Intravenous (IV) Pivekimab Sunirine Moves Through the Body in Pediatric Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML)

for
Acute Myeloid Leukemia
Location: Valhalla NY, Nashville TN, Dallas TX, Palo Alto CA
Sponsor: AbbVie

Sex: All

Age: 0 - 17

Code: NCT07306832

Phase1, Recruiting
Active & ResponsiveNew

Ziftomenib for the Treatment of Patients With NPM1 Mutated or KMT2A Rearranged Acute Myeloid Leukemia Not Eligible for Standard Therapy

for
Acute Myeloid Leukemia
Location: Columbus OH
Sponsor: Uma Borate

Sex: All

Age: 18+

Code: NCT06930352

Phase2, Recruiting
Active & Responsive

PLAT-08: A Study Of SC-DARIC33 CAR T Cells In Pediatric And Young Adults With Relapsed Or Refractory CD33+ AML

for
Acute Myeloid Leukemia, Acute Myeloid Leukemia Refractory,
Location: Seattle WA
Sponsor: Seattle Children's Hospital

Sex: All

Age: 0 - 30

Code: NCT05105152

Phase1, Recruiting
Active & Responsive

Study of REM-422 in Patients With AML or Higher Risk MDS

for
Myelodysplastic Syndromes,
Location: Boston MA, New York NY, Tampa FL, Houston TX, Duarte CA
Sponsor: Remix Therapeutics

Sex: All

Age: 18+

Code: NCT06297941

Phase1, Recruiting

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Active & Responsive

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

for
Hematologic Malignancy, Acute Leukemia, Remission,
Location: Minneapolis MN
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 0 - 60

Code: NCT05735717

Phase2, Recruiting
Active & Responsive

Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors

for
Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia,
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: All

Age: 0 - 21

Code: NCT02508038

Phase1, Recruiting
Active & Responsive

Expanded/Activated Gamma Delta T-cell Infusion Following Hematopoietic Stem Cell Transplantation and Post-transplant Cyclophosphamide

for
Acute Myeloid Leukemia, Chronic Myeloid Leukemia,
Location: Columbus OH, Westwood KS
Sponsor: University of Kansas Medical Center

Sex: All

Age: 18 - 65

Code: NCT03533816

Phase1, Recruiting
Active & Responsive

Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

for
Acute Myeloid Leukemia
Location: Halifax, Boston MA, New Haven CT, Queens NY,
Sponsor: PedAL BCU, LLC

Sex: All

Age: 0 - 21

Code: NCT05183035

Phase3, Recruiting
Active & Responsive

Interferon-γ (IFN-γ) With Donor Leukocyte Infusion to Treat Relapsed Acute Myeloid Leukemia and Myelodysplastic Syndromes Post Allogeneic Hematopoietic Stem Cell Transplantation

for
Acute Myeloid Leukemia, Myelodysplastic Syndromes
Location: Pittsburgh PA, St Louis MO, Seattle WA
Sponsor: Sawa Ito, MD

Sex: All

Age: 18+

Code: NCT06529731

Phase2, Recruiting
Active & Responsive

Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT)

for
Hematologic Malignancy, GvHD, GVHD,Acute, GVHD, Chronic,
Location: Boston MA, New York NY, Minneapolis MN, Seattle WA,
Sponsor: Tr1X, Inc.

Sex: All

Age: 18+

Code: NCT06462365

Phase1, Recruiting
Active & Responsive

CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant

for
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia,
Location: Boston MA, Atlanta GA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18 - 70+

Code: NCT06059391

Phase2, Recruiting
Active & Responsive

Clonal Hematopoiesis Chemotherapy and Radiation Effects Study

for
Lung Cancer (Diagnosis), Osteochondroma, Spitz Nevus,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT07675967

Recruiting
Active & Responsive

CART123 Cells With or Without Ruxolitinib in Relapsed/Refractory Acute Myeloid Leukemia

for
Acute Myeloid Leukemia (AML)
Location: Philadelphia PA
Sponsor: Stephan Grupp MD PhD

Sex: All

Age: 0 - 29

Code: NCT07464951

Phase1, Recruiting
Active & Responsive

A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant

for
Accelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive,
Location: Boston MA, Atlanta GA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18 - 70+

Code: NCT07020533

Phase1, Recruiting
Active & Responsive

Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies

for
AML (Acute Myeloid Leukemia), Glioma, Cholangiocarcinoma,
Location: New York NY, Orange CA
Sponsor: Rigel Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07486713

Recruiting
Active & Responsive

A Study of the Combination of Ivosidenib, Azacitidine, and Venetoclax Followed by Ivosidenib Alone in People With Acute Myeloid Leukemia

for
Acute Myeloid Leukemia
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 60+

Code: NCT07392242

Phase2, Recruiting
Active & Responsive

UPDATE AML: UPdated Disease Monitoring And Treatment for Enhanced Outcomes for Pediatric AML

for
Acute Myeloid Leukemia, Pediatric AML
Location: Houston TX
Sponsor: Baylor College of Medicine

Sex: All

Age: 0 - 30

Code: NCT07059975

Early_phase1, Recruiting
Active & Responsive

CD64 CAR T Cell Therapy in Adults With Relapsed and/or Refractory AML

for
Refractory Acute Myeloid Leukemia (AML),
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 18+

Code: NCT07347418

Phase1, Recruiting
Active & Responsive

FH-FOLR1 Chimeric Antigen Receptor T Cell Therapy for Treating Pediatric Patients With Relapsed or Refractory Acute Myeloid Leukemia

for
Recurrent Childhood Acute Myeloid Leukemia,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 0 - 6

Code: NCT06609928

Phase1, Recruiting