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Pan-tumor MRD Study

for
Muscle Invasive Bladder Urothelial Carcinoma, Esophageal Cancer,
Location: Maumee OH, San Diego CA
Sponsor: Flatiron Health

Sex: All

Age: 18+

Code: NCT06605404

Recruiting

Bladder Bank (a Prospective Banking Study)

for
Bladder Carcinoma
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06109857

Recruiting

FORAGER-1: A Study of Vepugratinib (LY3866288; LOXO-435) in Participants With Cancer With a Change in a Gene Called FGFR3

for
Urinary Bladder Neoplasms, Neoplasm Metastasis,
Location: Boston MA, The Bronx NY, New York NY, Burlington VT,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT05614739

Phase1, Recruiting

Enfortumab Vedotin Plus Pembrolizumab With Selective Bladder Sparing for Treatment of Muscle-invasive Bladder Cancer

for
Muscle Invasive Bladder Urothelial Carcinoma
Location: New York NY, Philadelphia PA, Indianapolis IN,
Sponsor: Matthew Galsky

Sex: All

Age: 18+

Code: NCT06809140

Phase2, Recruiting

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

for
Bladder Carcinoma, Ureter Carcinoma, Renal Pelvis Carcinoma,
Location: East Brunswick NJ, Philadelphia PA, York PA,
Sponsor: Guardant Health, Inc.

Sex: All

Age: 18+

Code: NCT05059444

Recruiting

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Personalized Cancer Vaccine (PCV) Strategy in Patients With Solid Tumors and Molecular Residual Disease

for
Muscle-Invasive Bladder Carcinoma,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT06529822

Phase1, Recruiting

A Clinical Study of Intismeran Autogene (V940) and BCG in People With Bladder Cancer (V940-011/INTerpath-011)

for
Urinary Bladder Neoplasms,
Location: Moncton, Sherbrooke, New York NY, Bala-Cynwyd PA,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06833073

Phase2, Recruiting

At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer

for
Advanced Anal Carcinoma, Advanced Biliary Tract Carcinoma,
Location: Jacksonville FL, Grand Forks ND
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT05969860

Phase2, Recruiting

Virtual Histology of the Bladder Wall for Bladder Cancer Staging

for
Urinary Bladder Neoplasms
Location: Pittsburgh PA
Sponsor: Jodi Maranchie

Sex: All

Age: 18 - 70+

Code: NCT04369560

Early_phase1, Recruiting

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

for
Carcinoma, Transitional Cell, Urinary Bladder Neoplasms,
Location: New York NY, East Brunswick NJ, Norfolk VA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07218380

Phase3, Recruiting

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

for
Amyloidosis, Basal Cell Carcinoma, Biliary Tract Carcinoma,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT07285044

Phase2, Recruiting

Studying the Relationship of Patient Positioning and Intravesical Bacillus Calmette Guerin Dwell Time to Improve the Treatment of Non-muscle Invasive Bladder Cancer

for
Non-Muscle Invasive Bladder Carcinoma
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07474519

Recruiting

A Study to Assess Real-World Use and Outcomes of TAR-200 for Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) in the United States

for
Non-Muscle Invasive Bladder Neoplasms
Location: Syracuse NY, North Charleston SC, Charlotte NC,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT07309445

Recruiting

Enfortumab Vedotin With or Without Pembrolizumab in Rare Genitourinary Tumors (E-VIRTUE)

for
Adenocarcinoma of the Bladder,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06041503

Phase2, Recruiting

Trifluridine/Tipiracil + Oxaliplatin in Participants With Advanced or Metastatic Biliary Tract Cancer

for
Biliary Tract Cancer, Biliary Tract Neoplasms,
Location: Cleveland OH
Sponsor: Case Comprehensive Cancer Center

Sex: All

Age: 19+

Code: NCT07146646

Phase2, Recruiting

A Study to Evaluate TAR-210 Versus Intravesical Chemotherapy Treatment in Participants With High Risk Non-Muscle-Invasive Bladder Cancer

for
Non-Muscle Invasive Bladder Neoplasms
Location: Plymouth MA, Voorhees Township NJ, Bala-Cynwyd PA,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT06919965

Phase3, Recruiting

Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)

for
Urothelial Cancer, Urinary Bladder Neoplasms
Location: Montreal, Norfolk VA, Newark DE, Fairfield OH,
Sponsor: Astellas Pharma Global Development, Inc.

Sex: All

Age: 18+

Code: NCT07566156

Phase3, Recruiting

Perioperative Durvalumab With Neoadjuvant ddMVAC or Gemcitabine/Cisplatin in Patients With Muscle-invasive Bladder Cancer (NIAGARA-2)

for
Urinary Bladder Neoplasms, Immune Checkpoint Inhibitors,
Location: Quebec, Sherbrooke, Hamilton
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06960577

Phase3, Recruiting

A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors

for
Urothelial Carcinoma Bladder,
Location: New York NY, Glen Burnie MD, Miami FL, Pittsburgh PA,
Sponsor: Aktis Oncology, Inc.

Sex: All

Age: 18+

Code: NCT07020117

Phase1, Recruiting

The Vanguard Study: Testing a New Way to Screen for Cancer

for
Bladder Carcinoma, Breast Carcinoma, Colorectal Carcinoma,
Location: Portsmouth VA, Norfolk VA, Bethesda MD, Richmond VA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 45 - 70+

Code: NCT06995898

Recruiting