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Serial Circulating Tumor DNA (ctDNA) Monitoring During Adjuvant Capecitabine in Early Triple-negative Breast Cancer

for
Triple Negative Breast Cancer, Breast Cancer
Location: Stanford CA
Sponsor: Stanford University

Sex: All

Age: 18+

Code: NCT04768426

Phase2, Recruiting

Mobile Health Patient Navigation for the Improvement of Screening and the Early Detection of Breast Cancer in Women Accessing Primary Care Clinics in Kenya

for
Breast Carcinoma
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT07764796

Recruiting

Pilot Study of Aerobic Exercise During Immune Checkpoint Inhibitor Therapy in Early-Stage TNBC

for
Aerobic Exercise, Early Stage Triple Negative Breast Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07216495

Recruiting

Phase II Trial of Ivonescimab in Combination With Carboplatin + Docetaxel in Patients With Early-Stage Triple Negative Breast Cancer

for
TNBC, TNBC - Triple-Negative Breast Cancer,
Location: Los Angeles CA, Torrance CA
Sponsor: Cedars-Sinai Medical Center

Sex: All

Age: 18+

Code: NCT07017673

Phase2, Recruiting

Ultrasound Imaging and Spectroscopy as Early Indicators of Locally-Advanced Breast Cancer Response

for
Breast Cancer
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18+

Code: NCT04134780

Recruiting

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A Phase 2 Single-Arm Open-Label Pilot Trial Evaluating Zanidatamab (ZW25) in Patients With Early Stage HER2/Neu Positive (HER2+) Breast Cancer (BC)

for
Breast Cancer, HER2-positive
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: Female

Age: 18+

Code: NCT05035836

Phase2, Recruiting

Active Surveillance in Older Women With ER+ Breast Cancer

for
Early Stage Estrogen Receptor (ER) Positive Breast Cancer
Location: Pittsburgh PA
Sponsor: University of Pittsburgh

Sex: Female

Age: 70+

Code: NCT07262138

Recruiting

Tirzepatide for Weight Loss Intervention in Early-Stage Hormone Receptor Positive/HER2 Negative Breast Cancer

for
Hormone Receptor-Positive Breast Cancer,
Location: Long Branch NJ, Elizabeth NJ, Newark NJ, Livingston NJ,
Sponsor: Rutgers, The State University of New Jersey

Sex: All

Age: 18+

Code: NCT06518837

Phase2, Recruiting

DecipHER Trial - DC1 Tx for Early-Stage TNBC and ER Low Positive Breast Cancer

for
Triple Negative Breast Cancer, HER2-negative Breast Cancer
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT05504707

Phase1, Recruiting

Avera Cancer Sequencing and Analytics Protocol (ASAP)

for
Cancer, Cancer Diagnosis, Early Detection of Cancer,
Location: Marshall MN, Sioux Falls SD, Yankton SD, Mitchell SD,
Sponsor: Avera McKennan Hospital & University Health Center

Sex: All

Age: 18+

Code: NCT05142033

Recruiting

Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

for
Healthy Volunteer, Prostate Cancer, Head and Neck Cancer,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT04354064

Recruiting

BettER: Biomarker Driven Early Therapeutic Selection in Patients With HR+ HER2- Metastatic or Unresectable Breast Cancer

for
Metastatic Breast Cancer, Unresectable Breast Cancer
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT05977036

Recruiting

Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform

for
Early Stage Triple-Negative Breast Carcinoma,
Location: Jacksonville FL, Rochester MN, Phoenix AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06349642

Recruiting

A Study Evaluating the Safety, Pharmacokinetics and Early Efficacy of AVA6000 in Solid Tumours

for
Salivary Gland Tumor, Urothelial Carcinoma, Ovarian Carcinoma,
Location: New York NY, Houston TX, Seattle WA
Sponsor: Avacta Life Sciences Ltd

Sex: All

Age: 18+

Code: NCT04969835

Phase1, Recruiting

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

for
Brain Cancer, Breast Cancer, Bladder Cancer, Cervical Cancer,
Location: Miami FL, Florence SC, Charleston SC, Cleveland OH,
Sponsor: Adela, Inc

Sex: All

Age: 40+

Code: NCT05366881

Recruiting

Functional Precision Oncology to Predict, Prevent, and Treat Early Metastatic Recurrence of TNBC

for
Breast Cancer Recurrent
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: All

Age: 18+

Code: NCT05464082

Phase2, Recruiting

Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma

for
Mesothelioma, Malignant Mesothelioma (MM),
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT05960773

Phase2, Recruiting

Ph2 Study for Optimization of Adjunct Systemic Therapy in HER2+ Patients, MolecularPCR Trial

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07407920

Phase2, Recruiting

Personalized Vaccine Immunotherapy in Combination With Checkpoint Inhibitor for Treatment of Triple Negative Breast Cancer

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT06324240

Phase1, Recruiting

ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Brewer ME, Rockport ME, Brunswick ME, South Portland ME,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT06876714

Phase3, Recruiting