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BettER: Biomarker Driven Early Therapeutic Selection in Patients With HR+ HER2- Metastatic or Unresectable Breast Cancer

for
Metastatic Breast Cancer, Unresectable Breast Cancer
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT05977036

Recruiting

Phase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067

for
Cancer, Solid Tumor, Melanoma, Renal Cell Carcinoma,
Location: Boston MA, New Haven CT, Buffalo NY, Tampa FL,
Sponsor: Simcha IL-18, Inc.

Sex: All

Age: 18+

Code: NCT04787042

Phase1, Phase2, Recruiting

Triple Negative Breast Cancer and Germline Hereditary Breast and Ovarian Cancer Mutation Carrier Registry

for
Breast Cancer, Hereditary Breast and Ovarian Cancer
Location: Lee's Summit MO, Kansas City MO, Kansas City KS,
Sponsor: University of Kansas Medical Center

Sex: All

Age: 0+

Code: NCT02302742

Recruiting

Tablet-based Mobile Health Ultrasound for Point-of-care Breast Cancer Diagnosis in Nigeria (Mobile Health: Technology and Outcomes in Low and Middle-Income Countries)

for
Breast Cancer, Breast Cancer Female
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female

Age: 18+

Code: NCT05561842

Recruiting

Stereotactic Radiation & Abemaciclib in the Management of HR+/HER2- Breast Cancer Brain Metastases

for
Brain Metastases, HR+ Metastatic Breast Cancer
Location: Columbus OH
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT04923542

Phase1, Phase2, Recruiting

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CD40 Agonist, Flt3 Ligand, and Chemotherapy in HER2 Negative Breast Cancer

for
HER2-negative Breast Cancer, Metastatic Breast Cancer
Location: Baltimore MD, Chapel Hill NC, Chicago IL, Dallas TX,
Sponsor: University of Texas Southwestern Medical Center

Sex: All

Age: 18 - 70+

Code: NCT05029999

Phase1, Recruiting

THRIVE Well Cancer FDTN/Exercise_Creatine Supplementation

for
Breast Cancer, Breast Cancer Female, Muscle Weakness
Location: Galveston TX
Sponsor: The University of Texas Medical Branch, Galveston

Sex: Female

Age: 18 - 70+

Code: NCT06395506

Recruiting

Observational Study of Bone Complications in People With Post-menopausal Breast Cancer Who Have Stopped Treatment With Denosumab and Aromatase Inhibitors

for
Breast Cancer
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female

Age: 18+

Code: NCT05590949

Recruiting

Resistance Training and Post Workout Protein to Improve Body Composition During Neoadjuvant Chemotherapy for Breast Cancer

for
Cancer, Breast Cancer
Location: Pittsburgh PA
Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Sex: Female

Age: 20 - 70+

Code: NCT06858449

Recruiting

Neoadjuvant Dupilumab, Pembrolizumab, Paclitaxel, and Carboplatin in Locally Advanced Triple Negative Breast Cancer

for
Locally Advanced Triple Negative Breast Cancer,
Location: New York NY
Sponsor: Rima Patel

Sex: All

Age: 18+

Code: NCT06637306

Early_phase1, Recruiting

A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors

for
Triple Negative Breast Cancer, Breast Cancer,
Location: Boston MA, New York NY, Fairfax VA, Jacksonville FL,
Sponsor: Day One Biopharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT05377996

Phase1, Phase2, Recruiting

Myeloid-Derived Suppressor Cell Function in Breast Cancer Patients

for
Breast Cancer
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: Female

Age: 18+

Code: NCT04022616

Recruiting

A Study Evaluating the Safety, Pharmacokinetics and Early Efficacy of AVA6000 in Solid Tumours

for
Salivary Gland Tumor, Urothelial Carcinoma, Ovarian Carcinoma,
Location: New York NY, Houston TX, Seattle WA
Sponsor: Avacta Life Sciences Ltd

Sex: All

Age: 18+

Code: NCT04969835

Phase1, Recruiting

Developing New Educational Materials About Genetic Testing for a Diverse Group of Cancer Patients

for
Educational Materials for Genetic Testing, Breast Cancer,
Location: Jamaica NY, Richmond Hill NY, Brooklyn NY, New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT04751435

Recruiting

A Phase 2 Single-Arm Open-Label Pilot Trial Evaluating Zanidatamab (ZW25) in Patients With Early Stage HER2/Neu Positive (HER2+) Breast Cancer (BC)

for
Breast Cancer, HER2-positive
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: Female

Age: 18+

Code: NCT05035836

Phase2, Recruiting

A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

for
Non-small Cell Lung Cancer,
Location: Boston MA, New York NY, New Brunswick NJ, Pittsburgh PA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT05877599

Phase1, Recruiting

Evaluation of Radiobiological Effects in Skin Toxicities for Breast Cancer Patients With Pencil Beam Scanning Proton Therapy

for
Breast Cancer, Breast Cancer Stage II, Breast Cancer Stage III,
Location: Knoxville TN
Sponsor: Thompson Cancer Survival Center

Sex: Female

Age: 18+

Code: NCT06006806

Recruiting

Kadcyla And Neratinib for Interception of HER2+ Breast Cancer With Molecular Residual Disease

for
Breast Cancer, HER2-positive Breast Cancer
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT05388149

Phase2, Recruiting

Cardiometabolic Screening Program

for
Breast Cancer, Early-stage Breast Cancer
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 18+

Code: NCT05386719

Recruiting

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

for
Breast Cancer
Location: South Weymouth MA, Danvers MA, Waltham MA, Boston MA,
Sponsor: Stemline Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06492616

Phase3, Recruiting