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Neoadjuvant Neratinib in Stage I-III HER2-Mutated Lobular Breast Cancers

for
Anatomic Stage I Breast Cancer, Anatomic Stage II Breast Cancer,
Location: Nashville TN, Dallas TX
Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All

Age: 18+

Code: NCT05919108

Phase2, Recruiting

Locally ablatiVe therApy in oLigO-pRogressive sOlid tUmorS (VALOROUS)

for
Breast Cancer, Oligoprogressive, Head and Neck Cancer, Sarcoma,
Location: Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18+

Code: NCT06103669

Recruiting

A Study of Enzalutamide, Enzalutamide in Combination With Mifepristone, or Chemotherapy in People With Metastatic Breast Cancer

for
Metastatic Breast Cancer
Location: Boston MA, Commack NY, Uniondale NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06099769

Phase2, Recruiting

A Study of Pembrolizumab and Cryoablation in People With Breast Cancer

for
Metastatic Breast Cancer, Breast Cancer, Breast Cancer Stage IV,
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06246968

Phase1, Recruiting

BRE-04: Window of Opportunity Trial of Preoperative Low Dose Azacitidine in High-Risk Early Stage Breast Cancer

for
Breast Cancer Invasive, Early-stage Breast Cancer,
Location: Chicago IL
Sponsor: University of Illinois at Chicago

Sex: All

Age: 18+

Code: NCT04891068

Phase2, Recruiting

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Facilitating Physical Activity Behavior and Health Outcomes in Breast Cancer Patients Receiving Chemotherapy

for
Breast Cancer
Location: Medicine Hat, Red Deer, Lethbridge, Calgary,
Sponsor: Athabasca University

Sex: Female

Age: 18 - 70+

Code: NCT01053468

Phase2, Recruiting

A Study of Abemaciclib and Radiation Therapy in People With Metastatic Breast Cancer

for
Metastatic Breast Cancer, Stage IV Breast Cancer, Breast Cancer,
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06678269

Phase1, Recruiting

First in Human Study of TUB-030 in Patients With Advanced Solid Tumors

for
Advanced Solid Tumors, HNSCC, SCLC, NSCLC,
Location: Boston MA, New York NY, New Haven CT, Miami FL, Toronto,
Sponsor: Tubulis GmbH

Sex: All

Age: 18+

Code: NCT06657222

Phase1, Phase2, Recruiting

Intercostobrachial Nerve Sparing to Reduce Post-Surgical Pain

for
Post-surgical Pain, Pain, Chronic, Intercostal Pain,
Location: Hamilton
Sponsor: McMaster University

Sex: Female

Age: 18+

Code: NCT03421522

Recruiting

Tart Cherry Juice as a Dietary Supplement for the Prevention of Paclitaxel-Induced Neuropathy

for
Breast Cancer, Breast Cancer Stage I, Breast Cancer Stage II,
Location: Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18+

Code: NCT06268665

Phase2, Recruiting

Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

for
Metastatic Breast Cancer
Location: Boston MA, New York NY, New Brunswick NJ, Montreal,
Sponsor: LeonaBio

Sex: All

Age: 18+

Code: NCT05696626

Phase3, Recruiting

TReatment of ADC-Refractory Breast CancEr With Dato-DXd or T-DXd: TRADE DXd

for
Breast Cancer, HER2-low Breast Cancer, Metastatic Breast Cancer,
Location: Boston MA, New Haven CT, The Bronx NY,
Sponsor: Ana C Garrido-Castro, MD

Sex: All

Age: 18+

Code: NCT06533826

Phase2, Recruiting

Optimizing Surgical Decisions in Young Adults With Breast Cancer

for
Breast Cancer Stage 0, Breast Cancer Stage I,
Location: Boston MA, New Haven CT, New York NY, Durham NC
Sponsor: Weill Medical College of Cornell University

Sex: Female

Age: 18 - 44

Code: NCT06275126

Recruiting

Pre-operative SABR With and Without Caloric Restriction for Early Stage Breast Cancer

for
Anatomic Stage 0 Breast Cancer AJCC v8,
Location: Philadelphia PA
Sponsor: Thomas Jefferson University

Sex: All

Age: 40+

Code: NCT04959474

Recruiting

Single Pre-Operative Radiation Therapy - With Delayed or No Surgery (SPORT-DNS)

for
Breast Cancer
Location: Montreal
Sponsor: Maisonneuve-Rosemont Hospital

Sex: Female

Age: 50+

Code: NCT05217966

Recruiting

Topical Betamethasone Versus Moisturizer in Preventing Radiation Dermatitis in Large-Breasted Patients Treated in the Prone Position

for
Breast Cancer, Radiation Dermatitis
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18+

Code: NCT06915857

Phase3, Recruiting

Gemcitabine and Ex Vivo Expanded Allogenic Universal Donor, TGFβi Natural Killer (NK) Cells With or Without Naxitamab (Danyelza) for the Treatment of Patients With Metastatic, GD2 Expressing, HER2 Negative Breast Cancer

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Columbus OH
Sponsor: Margaret Gatti-Mays

Sex: All

Age: 18+

Code: NCT06026657

Phase1, Phase2, Recruiting

Serial Circulating Tumor DNA (ctDNA) Monitoring During Adjuvant Capecitabine in Early Triple-negative Breast Cancer

for
Triple Negative Breast Cancer, Breast Cancer
Location: Stanford CA
Sponsor: Stanford University

Sex: All

Age: 18+

Code: NCT04768426

Phase2, Recruiting

First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer

for
Advanced Solid Tumors, Breast Cancer Recurrent, Ovarian Cancer,
Location: New York NY, Fairfax VA, Sarasota FL, Detroit MI,
Sponsor: Accent Therapeutics

Sex: All

Age: 18+

Code: NCT06799065

Phase1, Recruiting

A Comparison of Intra-operative Radiotherapy Boost With External Beam Radiotherapy Boost in Early Breast Cancer.

for
Early Breast Cancer
Location: Dobbs Ferry NY, Los Angeles CA, Morgantown WV,
Sponsor: University College, London

Sex: Female

Age: 0+

Code: NCT01792726

Recruiting