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A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors

for
Melanoma, Non-small Cell Lung Cancer,
Location: Fairfax VA, Pittsburgh PA, Grand Rapids MI, St Louis MO,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07115043

Phase1, Phase2, Recruiting

A Study for CTC Expression and cfDNA/RNA Assessment in Metastatic Breast Cancer Patients

for
Metastatic Breast Cancer (MBC)
Location: Pittsburgh PA
Sponsor: Menarini Silicon Biosystems, INC

Sex: All

Age: 18+

Code: NCT06833853

Recruiting

HERizon-Breast: A ctDNA-Guided Adaptive Study of Sequential Anti-HER2 Therapies and CNS Prophylaxis to Induce Long-Term Remission

for
Breast Cancer, HER2-positive Breast Cancer,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07459673

Phase2, Recruiting

IDOV-Immune for Advanced Solid Tumors

for
Colorectal Cancer, Pancreatic Cancer, Melanoma, Ovarian Cancer,
Location: St Louis MO, Houston TX, San Antonio TX
Sponsor: ViroMissile, Inc.

Sex: All

Age: 18+

Code: NCT06910657

Phase1, Recruiting

Safe and Explainable AI

for
Artifical Inteligence, Cardiology, Breast Cancer, Sepsis
Location: Philadelphia PA
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All

Age: 18+

Code: NCT06694181

Recruiting

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Adjuvant Chemoradiation and Biomarkers of Response in High-risk Breast Cancer

for
Breast Cancer, Breast Cancer Stage I, Breast Cancer Stage II,
Location: Charlottesville VA
Sponsor: University of Virginia

Sex: All

Age: 18+

Code: NCT05288777

Phase2, Phase3, Recruiting

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

for
Breast Cancer, Early Breast Cancer
Location: Winston-Salem NC, Irving TX, Aberdeen SD, Pierre SD
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT05774951

Phase3, Recruiting

Adapting the Tumor Board Model for Mental Illness and Cancer

for
Cancer, Severe Major Depression, Schizophrenia,
Location: Danvers MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT05837598

Recruiting

Impact of Intermittent Fasting on Biomarkers of Inflammation and Health-Related Quality of Life: A Feasibility Trial for Women With HR+/HER2- Early Breast Cancer

for
Breast Cancer
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: All

Age: 18+

Code: NCT06106477

Recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

for
Advanced Malignant Solid Neoplasm,
Location: Brewer ME, Augusta ME, Scarborough ME,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0+

Code: NCT05564377

Phase2, Recruiting

Neuromodulation of Cardiovascular Risks Associated With Cardiotoxic Chemotherapy

for
Breast Cancer, Lymphoma
Location: Oklahoma City OK
Sponsor: University of Oklahoma

Sex: All

Age: 18 - 70+

Code: NCT05921253

Early_phase1, Recruiting

Personalized Dendritic Cell Vaccine Pilot for High Risk TNBC After Neoadjuvant Therapy

for
Breast Cancer, Triple Negative Breast Cancer
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06435351

Early_phase1, Recruiting

Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

for
Advanced Breast Cancer
Location: Boston MA, Stony Brook NY, Mineola NY, New York NY,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06380751

Phase3, Recruiting

Marathon of Hope Cancer Centres Network Study for Ontario (MOHCCN-O)

for
Breast Cancer, Colorectal Cancer, Pancreas Cancer,
Location: Kingston, Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT05403177

Recruiting

Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer

for
Endocrine Tumors, Non-Small Cell Lung Cancer, Ovarian Cancer,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT03412877

Phase2, Recruiting

Non-Invasive Artificial Intelligence-Based Platform MonIToring Program (NIP IT!)

for
Breast Cancer, Melanoma, Gastrointestinal Neuroendocrine Tumor
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT05196087

Recruiting

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

for
Endometrial Cancer, Cervical Cancer, Ovarian Cancer,
Location: Boston MA, Mineola NY, New York NY, Fairfax VA,
Sponsor: SystImmune Inc.

Sex: All

Age: 18+

Code: NCT06293898

Phase1, Recruiting

ProAgio in Combination With Gemcitabine in Patients With Metastatic Triple Negative Breast Cancer

for
Triple Negative Breast Cancer
Location: Atlanta GA
Sponsor: ProDa BioTech, LLC

Sex: All

Age: 18+

Code: NCT06460298

Phase1, Phase2, Recruiting

A First-in-human, Phase I, Open-label, Multicenter Study of NM1F(Anti-PVRIG) in Patients With Advanced Solid Tumors

for
Ovarian Cancer, Melanoma, Triple Negative Breast Cancer,
Location: Fairfax VA, Dallas TX
Sponsor: Hefei TG ImmunoPharma Co., Ltd.

Sex: All

Age: 18+

Code: NCT05746897

Phase1, Recruiting

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

for
Oncology, Breast Cancer, Prostate Cancer, Gynecologic Cancer,
Location: Toronto, Pittsburgh PA, Milwaukee WI, Houston TX
Sponsor: UMC Utrecht

Sex: All

Age: 18+

Code: NCT04075305

Recruiting