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Active & Responsive

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

for
PIK3CA Mutation, HER2- Negative Breast Cancer,
Location: Boston MA, New Haven CT, New York NY, Hackensack NJ,
Sponsor: Relay Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06982521

Phase3, Recruiting
Active & Responsive

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

for
Breast Cancer, Endometrial Cancer, Ovarian Cancer,
Location: Boston MA, Fairfax VA, Orlando FL, Huntersville NC,
Sponsor: Terremoto Biosciences Inc.

Sex: All

Age: 18+

Code: NCT07109726

Phase1, Phase2, Recruiting
Active & Responsive

Feasibility Study for the SIRA-1000, SIRA® RFA Electrosurgical Device as an Adjunct to Breast Conserving Surgery

for
Breast Cancer, Breast-conserving Surgery,
Location: Galveston TX
Sponsor: Innoblative Designs, Inc.

Sex: Female

Age: 50+

Code: NCT07206121

Recruiting
Active & Responsive

Efficacy of Point Of Service Testing in MBC

for
Metastatic Cancer, Breast Cancer
Location: Kansas City KS
Sponsor: University of Kansas Medical Center

Sex: All

Age: 18+

Code: NCT03983577

Recruiting
Active & Responsive

The LYMPH Trial - Microsurgical Versus Conservative Treatment of Chronic Breast Cancer Associated Lymphedema

for
Lymphedema, Breast Cancer
Location: Boston MA, Montreal, St Louis MO, Vancouver
Sponsor: University Hospital, Basel, Switzerland

Sex: All

Age: 18+

Code: NCT05890677

Recruiting

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Active & Responsive

Trastuzumab Deruxtecan (T-DXd) in Patients Who Have Hormone Receptor-negative and Hormone Receptor-positive HER2-low or HER2 IHC 0 Metastatic Breast Cancer

for
Breast Cancer
Location: Boston MA, Summit NJ
Sponsor: Daiichi Sankyo

Sex: All

Age: 18+

Code: NCT05950945

Phase3, Recruiting
Active & Responsive

Near Infrared Spectroscopy (NIRS) as a Method for Measuring Oxidative Capacity of Skeletal Muscle Mitochondria in Breast Cancer and All Gynecological Cancer Patients

for
Breast Cancer, Gynecologic Cancers, Mitochondrial Function
Location: Greenville SC
Sponsor: University of South Carolina

Sex: Female

Age: 20+

Code: NCT06672497

Recruiting
Active & Responsive

Leflunomide in Patients With PTEN-Altered Advanced Solid Malignancies and HER2 Negative Breast Cancer

for
PTEN-Altered Advanced Solid Tumors and HER2 Negative Breast Cancer,
Location: New York NY
Sponsor: Deborah Doroshow

Sex: All

Age: 18+

Code: NCT04997993

Phase1, Recruiting
Active & Responsive

RAGE Inhibition to Decrease Cardiotoxicity in Women With Early Breast Cancer

for
Cancer Related Cognitive Decline, Non-metastatic Breast Cancer
Location: Hackensack NJ, Washington D.C. DC
Sponsor: Georgetown University

Sex: Female

Age: 18+

Code: NCT05256745

Phase1, Phase2, Recruiting
Active & Responsive

Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer

for
Breast Cancer, Breast Neoplasm, Breast Tumor,
Location: New York NY, Hampton VA, Baltimore MD, Fairfax VA,
Sponsor: Proton Collaborative Group

Sex: Female

Age: 50+

Code: NCT01766297

Phase2, Recruiting
Active & Responsive

Genomically Guided Radiation Therapy in the Management of Triple Negative Breast Cancer

for
Triple Negative Breast Cancer
Location: Tampa FL, Clearwater FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT05528133

Phase2, Recruiting
Active & Responsive

Breast cancEr, FITness and ExeRcise for Heart Health: The BE-FITTER Study

for
Breast Cancer, Disability Physical, Heart Failure,
Location: Edmonton
Sponsor: University of Alberta

Sex: Female

Age: 60+

Code: NCT06595147

Recruiting
Active & Responsive

Every Day Counts: A Lifestyle Program for Women With Metastatic Breast Cancer

for
Metastatic Breast Cancer
Location: Maywood IL, Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: Female

Age: 18+

Code: NCT03824145

Recruiting
Active & Responsive

Protein Needs Study

for
Colorectal Cancer, Breast Cancer
Location: Edmonton
Sponsor: University of Alberta

Sex: All

Age: 45 - 70+

Code: NCT04144907

Recruiting
Active & Responsive

Conformal Ablative Radiotherapy in Older Women (CARMEN) With Breast Cancer Undergoing Non-Operative Management

for
Breast Cancer Female
Location: Kansas City KS
Sponsor: University of Kansas Medical Center

Sex: Female

Age: 65+

Code: NCT07242118

Recruiting
Active & Responsive

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

for
Breast Neoplasms
Location: Rimouski, Boston MA, New Haven CT, Quebec,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06312176

Phase3, Recruiting
Active & Responsive

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

for
Triple Negative Breast Neoplasms
Location: Quebec, Chicoutimi, Mineola NY, New York NY,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06841354

Phase3, Recruiting
Active & Responsive

DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

for
Ductal Carcinoma in Situ
Location: New York NY, Englewood NJ, Richmond VA, Durham NC,
Sponsor: QuantumLeap Healthcare Collaborative

Sex: Female

Age: 18+

Code: NCT06075953

Phase2, Recruiting
Active & Responsive

Nephrotic Syndrome Study Network

for
Minimal Change Disease (MCD), Membranous Nephropathy,
Location: New Hyde Park NY, The Bronx NY, New York NY,
Sponsor: University of Michigan

Sex: All

Age: 0 - 70+

Code: NCT01209000

Recruiting
Active & Responsive

Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction

for
Breast Atypical Hyperplasia, Breast Carcinoma,
Location: Columbus OH, Ann Arbor MI, Kansas City KS
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 45 - 70+

Code: NCT06195306

Phase2, Recruiting