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A Phase 1b/2a Study of Pocenbrodib as Monotherapy and in Combination With Darolutamide in Participants With mCRPC

for
mCRPC (Metastatic Castration-resistant Prostate Cancer),
Location: New York NY, Baltimore MD, Fairfax VA, Durham NC,
Sponsor: Pathos AI, Inc.

Sex: Male

Age: 18+

Code: NCT06785636

Phase1, Phase2, Recruiting

A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.

for
Metastatic Castration-Resistant Prostate Cancer
Location: Halifax, Chicoutimi, The Bronx NY, Montreal,
Sponsor: Pfizer

Sex: Male

Age: 18+

Code: NCT06629779

Phase3, Recruiting

Anti-tumour Activity of (177Lu) rhPSMA-10.1 Injection

for
Prostate Cancer,
Location: Miami FL, Atlanta GA, Omaha NE
Sponsor: Blue Earth Therapeutics Ltd

Sex: Male

Age: 18+

Code: NCT05413850

Phase1, Phase2, Recruiting

A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer

for
Prostate Cancer,
Location: Bala-Cynwyd PA, Towson MD, Myrtle Beach SC,
Sponsor: Astellas Pharma Global Development, Inc.

Sex: Male

Age: 18+

Code: NCT04729114

Phase1, Recruiting

First-in-human Study of 225Ac-PSMA-Trillium (BAY 3563254) in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)

for
Advanced Metastatic Castration-resistant Prostate Cancer,
Location: Sherbrooke, Montreal, Toronto, Hamilton, Vancouver
Sponsor: Bayer

Sex: All

Age: 18+

Code: NCT06217822

Phase1, Recruiting

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A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With REGN5678 for Adult Participants With Advanced Prostate Cancer

for
Metastatic Castration-resistant Prostate Cancer
Location: New Haven CT, New Brunswick NJ, Philadelphia PA,
Sponsor: Regeneron Pharmaceuticals

Sex: Male

Age: 18+

Code: NCT05125016

Phase1, Phase2, Recruiting

A Study of NX-1607 in Adults With Advanced Malignancies

for
Ovarian Cancer, Epithelial, Gastric Cancer,
Location: Charlottesville VA, Chapel Hill NC, Chicago IL,
Sponsor: Nurix Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05107674

Phase1, Recruiting

Study of Apalutamide With Carotuximab in Metastatic, Castration-Resistant Prostate Cancer

for
Castration-resistant Prostate Cancer
Location: Salt Lake City UT, Duarte CA, Los Angeles CA
Sponsor: Edwin Posadas, MD

Sex: Male

Age: 18+

Code: NCT05534646

Phase2, Recruiting

Study of PF-07248144 in Advanced or Metastatic Solid Tumors

for
Locally Advanced or Metastatic ER+ HER2- Breast Cancer,
Location: New Haven CT, Edgewood KY, Louisville KY, Nashville TN,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT04606446

Phase2, Recruiting

Study Evaluating Dosimetry, Randomized Dose Optimization, Dose Escalation and Efficacy of Ac-225 Rosopatamab Tetraxetan in Participants With PSMA PET-Positive Castration-Resistant Prostate Cancer (CRPC)

for
PSMA PET-Positive Castration-Resistant Prostate Cancer
Location: Boston MA, New York NY, Durham NC, Cleveland OH,
Sponsor: Convergent Therapeutics

Sex: Male

Age: 18+

Code: NCT06549465

Phase2, Recruiting

Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors

for
Advanced HR+/HER2- Breast Cancer,
Location: Atlanta GA, Nashville TN, San Antonio TX
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07288359

Phase1, Phase2, Recruiting

XL092 in Patients With Metastatic Castration-Resistant Prostate Cancer

for
Metastatic Castration-resistant Prostate Cancer
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: Male

Age: 18+

Code: NCT06568562

Phase2, Recruiting

Fatty Acid Synthase Inhibition in Castration Refractory Prostate Cancer

for
Prostate Cancer, Refractory Cancer,
Location: Winston-Salem NC, Salisbury NC
Sponsor: Wake Forest University Health Sciences

Sex: Male

Age: 18+

Code: NCT04337580

Phase2, Recruiting

[Lu-177]Ludotadipep in Castration-resistant Prostate Cancer(CRPC): Investigation of Drug and Application

for
Metastatic Castration-resistant Prostate Cancer
Location: Gettysburg PA, Los Angeles CA
Sponsor: FutureChem

Sex: Male

Age: 18+

Code: NCT05458544

Phase1, Phase2, Recruiting

Study With [225Ac]Ac-FL-020 in mCRPC Participants

for
Metastatic Castration-resistant Prostate Cancer
Location: Charlottesville VA, Cleveland OH, Duarte CA, Irvine CA,
Sponsor: Full-Life Technologies GmbH

Sex: Male

Age: 18+

Code: NCT06492122

Phase1, Recruiting

Platinum and Taxane Chemo in Met Castration Resistant Prostate Cancer Patients With Alterations in DNA Damage Response Genes

for
Metastatic Castration-resistant Prostate Cancer,
Location: Quebec, Montreal, Ottawa, Toronto, Brampton, Kitchener,
Sponsor: Canadian Cancer Trials Group

Sex: Male

Age: 18+

Code: NCT06439225

Phase3, Recruiting

Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

for
Cervical Cancer, Breast Cancer, Colon Cancer, NSCLC,
Location: Glen Burnie MD, Lexington KY, Omaha NE
Sponsor: Orano Med Theranostics, SAS

Sex: All

Age: 18+

Code: NCT05283330

Phase1, Recruiting

Evaluation of the Change in PSMA Expression in Prostate Cancer in Response to Hormonal Therapy

for
Castration Resistant Prostate Cancer,
Location: Portland OR
Sponsor: OHSU Knight Cancer Institute

Sex: Male

Age: 18+

Code: NCT05919329

Recruiting

Dose-Escalation Study of Cabozantinib in Combination With Lutetium-177 (177Lu)-PSMA-617 in Patients With Metastatic Castration-Resistant Prostate Cancer

for
Metastatic Castration-resistant Prostate Cancer
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: Male

Age: 18+

Code: NCT05613894

Phase1, Recruiting

REGN15505 (PSMAx4-1BB) Alone or in Combination With Cemiplimab or REGN4336 (PSMAxCD3) in Adult Patients With Metastatic Castration-Resistant Prostate Cancer and Clear Cell Renal Cell Carcinoma

for
Metastatic Castration-Resistant Prostate Cancer (mCRPC),
Location: Tampa FL, Zion IL, Houston TX, Goodyear AZ, Duarte CA
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07594106

Phase1, Phase2, Recruiting