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PSCA-Targeting CAR-T Cells Plus or Minus Radiation for the Treatment of Patients With PSCA+ Metastatic Castration-Resistant Prostate Cancer

for
Castration-Resistant Prostate Carcinoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: Male

Age: 18+

Code: NCT05805371

Phase1, Recruiting

Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body

for
Castration-Resistant Prostate Carcinoma,
Location: Millville DE, Lewes DE, Rehoboth Beach DE,
Sponsor: SWOG Cancer Research Network

Sex: Male

Age: 18+

Code: NCT06470243

Phase3, Recruiting

Fecal Microbiota Transplant and Pembrolizumab for Men With Metastatic Castration Resistant Prostate Cancer.

for
Prostate Cancer, Prostate Cancer Metastatic
Location: Portland OR
Sponsor: Julie Graff, MD

Sex: Male

Age: 18+

Code: NCT04116775

Phase2, Recruiting

Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

for
Prostate Cancer
Location: New Haven CT, New York NY, Philadelphia PA, Fairfax VA,
Sponsor: Amgen

Sex: Male

Age: 18+

Code: NCT04221542

Phase1, Recruiting

A Phase I/II Study of PDS01ADC With Docetaxel and Abiraterone in Adults With Metastatic Castration Sensitive and PDS01ADC With Docetaxel in Castration Resistant Prostate Cancer

for
Cancer Of Prostate, Prostate Neoplasms
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: Male

Age: 18 - 70+

Code: NCT04633252

Phase1, Phase2, Recruiting

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Tesetaxel in Chemotherapy-naive Patients With Progressive, Castration-resistant Prostate Cancer

for
Prostate Cancer
Location: New York NY, New Brunswick NJ, Ann Arbor MI, Madison WI
Sponsor: Genta Incorporated

Sex: Male

Age: 18+

Code: NCT01296243

Phase2, Recruiting

Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer

for
Prostate Cancer
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: Male

Age: 18+

Code: NCT06059118

Phase2, Recruiting

Phase I Study of 225Ac-J591 Plus 177Lu-PSMA Small Molecule for Progressive Metastatic Castration Resistant Prostate Cancer

for
Prostate Cancer
Location: New York NY, Brooklyn NY
Sponsor: Weill Medical College of Cornell University

Sex: Male

Age: 18 - 70+

Code: NCT04886986

Phase1, Recruiting

177Lu-PSMA-617 With Liver Directed Therapy in Metastatic Castration Resistant Prostate Cancer

for
Metastatic Prostate Cancer, Prostate Cancer
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: Male

Age: 18+

Code: NCT07145177

Phase1, Recruiting

177^Lu-PSMA-617 in Combination With Sipuleucel-T for the Treatment of Metastatic Castration-Resistant Prostate Cancer

for
Metastatic Castration-Resistant Prostate Adenocarcinoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: Male

Age: 18+

Code: NCT07219147

Phase1, Recruiting

Phase I/II Trial of Pembrolizumab and Androgen-receptor Inhibitor With or Without 225Ac-J591 for Progressive Metastatic Castration Resistant Prostate Cancer

for
Prostate Cancer
Location: New York NY, Brooklyn NY
Sponsor: Weill Medical College of Cornell University

Sex: Male

Age: 18+

Code: NCT04946370

Phase1, Phase2, Recruiting

Bipolar Androgen Therapy (BAT) and Radium-223 (RAD) in Metastatic Castration-resistant Prostate Cancer (mCRPC)

for
Prostate Adenocarcinoma, Metastatic Prostate Adenocarcinoma,
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: Male

Age: 18+

Code: NCT04704505

Phase2, Recruiting

COMPASS Study for Metastatic Castration-resistant Prostate Cancer

for
Prostate Cancer
Location: Durham NC, Ann Arbor MI, Madison WI, San Francisco CA
Sponsor: Duke University

Sex: Male

Age: 18+

Code: NCT07050433

Recruiting

Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression

for
Castration Resistant Metastatic Prostate Cancer
Location: Boston MA, Baltimore MD, Minneapolis MN, Omaha NE,
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: Male

Age: 18 - 70+

Code: NCT04363164

Phase2, Recruiting
New

External Beam and Radioligand Radiotherapy for mCRPC

for
Prostate Cancer Metastatic Castration-Resistant
Location: Montreal
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: Male

Age: 0+

Code: NCT07354594

Phase2, Recruiting

18F-Fluciclovine PET/CT Impact on Predicting Clinical Outcome of 177Lu-PSMA-617 Therapy in Patients With Prostate Cancer

for
Prostatic Neoplasms, Prostatic Neoplasms, Castration-Resistant,
Location: Los Angeles CA
Sponsor: VA Greater Los Angeles Healthcare System

Sex: Male

Age: 18+

Code: NCT06706921

Recruiting

A Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate Cancer

for
Metastatic Castration-resistant Prostate Neoplasms,
Location: Mineola NY, Brooklyn NY, New York NY, Philadelphia PA,
Sponsor: Janssen Research & Development, LLC

Sex: Male

Age: 18+

Code: NCT05818683

Phase1, Recruiting

Use of SPECT-CT for Comparison of Dosimetry Methods in PSMA-targeted Radioligand Therapy (SPECTacular Study)

for
Metastatic Castration-resistant Prostate Cancer
Location: Grand Rapids MI
Sponsor: BAMF Health

Sex: Male

Age: 18+

Code: NCT05823402

Recruiting

Autologous Gamma Delta T Cells to Target Prostate Stem Cell Antigen in mCRPC

for
Metastatic Castration-resistant Prostate Cancer
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: Male

Age: 18+

Code: NCT06193486

Phase1, Recruiting

A Study of SYNC-T Therapy SV-102 in Participants With Metastatic Castration-Resistant Prostate Cancer

for
Metastatic Castration-resistant Prostate Cancer
Location: Lake Success NY, New York NY, Miami FL, Pittsburgh PA,
Sponsor: Syncromune, Inc.

Sex: Male

Age: 18+

Code: NCT06533644

Phase2, Recruiting