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Active & Responsive

A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy

for
Drug Resistant Epilepsy, Epilepsy, Seizures, Focal, Seizure,
Location: Boston MA, Charlottesville VA, Palo Alto CA
Sponsor: NaviFUS Corporation

Sex: All

Age: 18+

Code: NCT06388707

Phase1, Phase2, Recruiting
Active & Responsive

Diagnosing Epilepsy To EffeCT Change Long-Term Follow-Up

for
Epilepsy, Epilepsy (Treatment Refractory)
Location: Boston MA, New Haven CT, Philadelphia PA, Durham NC,
Sponsor: Epiminder America, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07110454

Recruiting
Active & Responsive

Real-World Evidence in Patient-Reported Outcomes for Medical Cannabis (MC-RWE)

for
Pain, Sleep, Anxiety, Depression, Epilepsy
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 19+

Code: NCT04526093

Recruiting
Active & Responsive

VNS Prospective Neuromodulation of Immune and Gastrointestinal Systems

for
Autoimmune Diseases, Epilepsy, Autonomic Dysfunction,
Location: Louisville KY, Salt Lake City UT
Sponsor: University of Louisville

Sex: All

Age: 0 - 60

Code: NCT03953768

Recruiting
Active & Responsive

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

for
Rare Disorders, Undiagnosed Disorders,
Location: Sioux Falls SD
Sponsor: Sanford Health

Sex: All

Age: 0+

Code: NCT01793168

Recruiting

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Active & Responsive

Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics And Pharmacodynamics of SIF001 in Healthy Subjects and in Epilepsy Patients

for
Epilepsy, Healthy Volunteer
Location: Bathesda MD, Tamarac FL, Weston FL, Amherst NY,
Sponsor: Suninflam Inc

Sex: All

Age: 18 - 70

Code: NCT07051629

Phase1, Recruiting
Active & Responsive

Ketogenic Diet for New-Onset Absence Epilepsy

for
Absence Epilepsy, Ketogenic Dieting, Epilepsy, Absence
Location: Baltimore MD
Sponsor: Johns Hopkins University

Sex: All

Age: 3 - 12

Code: NCT04274179

Phase3, Recruiting
Active & Responsive

Molecular Genetic Mechanisms of Infantile Epilepsies and the Impact of Genetic Diagnosis

for
Neonatal Epilepsy, Infantile Epilepsy
Location: Boston MA
Sponsor: Boston Children's Hospital

Sex: All

Age: 0+

Code: NCT06701084

Recruiting
Active & Responsive

AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy

for
Mesial Temporal Lobe Epilepsy
Location: Boston MA, Lebanon NH, Hackensack NJ, New Brunswick NJ,
Sponsor: UniQure Biopharma B.V.

Sex: All

Age: 18 - 70+

Code: NCT06063850

Phase1, Phase2, Recruiting
Active & Responsive

Localizing Epileptic Networks Using MRI and iEEG

for
Epilepsy, Epilepsy Intractable, Epilepsy, Temporal Lobe
Location: Philadelphia PA
Sponsor: University of Pennsylvania

Sex: All

Age: 18+

Code: NCT04649008

Early_phase1, Recruiting
Active & Responsive

Microgrid II - Electrocorticography Signals for Human Hand Prosthetics

for
Epilepsy Intractable
Location: Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT03289572

Recruiting
Active & Responsive

Optimization of Deep Brain Stimulation Parameters in Patients With Medically Refractory Epilepsy

for
Refractory Epilepsy, Deep Brain Stimulation
Location: Minneapolis MN
Sponsor: University of Minnesota

Sex: All

Age: 18+

Code: NCT05493722

Early_phase1, Recruiting
Active & Responsive

Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))

for
Mesial Temporal Lobe Epilepsy
Location: Boston MA, Lebanon NH, Great Neck NY, New York NY,
Sponsor: Neurona Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT05135091

Phase3, Recruiting
Active & Responsive

Investigating Phenotypic, Epigenetic, and NeuroGenetic Traits in Rare and Ultra-rare Neurodevelopmental Disorders (Project PENGUIN)

for
Baker Gordon Syndrome, Rare Neurodevelopmental Conditions,
Location: Columbia MO
Sponsor: University of Missouri-Columbia

Sex: All

Age: 0 - 70+

Code: NCT07329257

Recruiting
Active & Responsive

Enhanced MRI Imaging in Healthy Participants and Participants With Epilepsy

for
Epilepsy, Temporal Lobe
Location: Edmonton
Sponsor: University of Alberta

Sex: All

Age: 18 - 64

Code: NCT06483061

Phase2, Recruiting
Active & Responsive

An Examination of Whether Infrared Light Therapy Can Reduce Stress in People With Epilepsy

for
Epilepsy
Location: North Miami FL, Warren OH, Cincinnati OH, Houston TX
Sponsor: Cynthia Kerson

Sex: All

Age: 18+

Code: NCT07509177

Recruiting
Active & Responsive

Registry and Natural History of Epilepsy-Dyskinesia Syndromes

for
Epilepsy-Dyskinesia, Epilepsy, Dyskinesia, EDS,
Location: Boston MA
Sponsor: Boston Children's Hospital

Sex: All

Age: 0 - 30

Code: NCT06967727

Recruiting
Active & Responsive

Ketogenic Diet for Prevention of Epileptic Spasms in Infantile Onset Genetic Epilepsies

for
Developmental and Epileptic Encephalopathies, Epileptic Spasms,
Location: Boston MA
Sponsor: Heather Olson

Sex: All

Age: 0

Code: NCT06700811

Phase1, Recruiting
Active & Responsive

Optimizing Therapy in Epilepsy Using Seizure Forecasts Via EEG and Wearables

for
Focal Epilepsy, Generalized Seizure, Drug Refractory Epilepsy
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18 - 70+

Code: NCT07012148

Recruiting
Active & Responsive

Registry and Natural History Study for Progressive Myoclonus Epilepsy Type 1 (EPM1)

for
Progressive Myoclonus Epilepsy Type 1, EPM1,
Location: Boston MA
Sponsor: Boston Children's Hospital

Sex: All

Age: 0+

Code: NCT06593951

Recruiting