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Phase 1/2 Study of BHB810 in Advanced Gastric and GEJ Adenocarcinoma

for
Gastric Cancer, Gastric Adenocarcinoma,
Location: Fairfax VA
Sponsor: BigHat Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT07529808

Phase1, Phase2, Recruiting

A Study of Cadonilimab Combined With Chemotherapy in People With Gastric or Gastroesophageal Junction Cancer

for
Gastric Cancer, Gastroesophageal-junction Cancer
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07631000

Phase2, Recruiting

Pilot Study of [68Ga]Ga-ABY-025 Imaging in Patients Undergoing Treatment With HER2-targeted Therapy

for
Locally Advanced Cancer, Metastatic Cancer, HER2,
Location: Nashville TN
Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All

Age: 18+

Code: NCT06828588

Early_phase1, Recruiting

A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal Cancers

for
Colorectal Cancer, Gastric Adenocarcinoma,
Location: Boston MA, Cincinnati OH, Duarte CA, Newport Beach CA
Sponsor: Dispatch Biotherapeutics

Sex: All

Age: 18+

Code: NCT07544589

Phase1, Recruiting

Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer

for
Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction , or Esophageal Adenocarcinoma,
Location: Langhorne PA, Bensalem PA, Horsham PA, Doylestown PA,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07392892

Phase2, Phase3, Recruiting

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Ivonescimab in Comb. With FOLFOX in Advanced HER2 Neg. GEA

for
Stomach Cancer Stage IV, Esophagus Cancer, Stomach Cancer
Location: Boston MA, Santa Monica CA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT07070466

Phase2, Recruiting

Registry Study of People Who Are Having an Esophagectomy and Are at High Risk of Anastomotic Leak

for
Esophageal Malignant Neoplasm Primary, Anastomotic Leak
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07449208

Recruiting

Trial Comparing Standard of Care Therapy With and Without Sequential Cytoreductive Intervention for Patients With Metastatic Foregut Adenocarcinoma and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid (ctDNA) Levels

for
Foregut Adenocarcinoma, Esophageal Adenocarcinoma,
Location: New Haven CT
Sponsor: Yale University

Sex: All

Age: 18 - 70+

Code: NCT07282912

Phase2, Recruiting

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)

for
Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma,
Location: Lake Success NY, New York NY, Salem VA, Toronto,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07221149

Phase2, Phase3, Recruiting

Obeticholic Acid for Prevention in Barrett's Esophagus

for
Barrett Esophagus, Esophageal Adenocarcinoma
Location: Chapel Hill NC, Cleveland OH, Ann Arbor MI, St Louis MO,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT04939051

Phase2, Recruiting

Sample Collection for Ongoing Research and Product Evaluation Study

for
Breast Cancer, Lung Cancer, Muscle Invasive Bladder Cancer,
Location: Austin TX
Sponsor: Natera, Inc.

Sex: All

Age: 18+

Code: NCT07318051

Recruiting

A Noninvasive and Screening miRNA Signature for Gastrointestinal Cancer

for
Hepatocellular Carcinoma (HCC), Cholangiocarcinoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07224750

Recruiting

A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

for
HNSCC, ESCC, Esophageal Adenocarcinoma, Gastric Adenocarcinoma,
Location: Boston MA, New Haven CT, Hackensack NJ, Philadelphia PA,
Sponsor: Normunity AccelCo, Inc.

Sex: All

Age: 18+

Code: NCT07182149

Phase1, Recruiting

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

for
Ovarian Neoplasms, Breast Neoplasms,
Location: Boston MA, New York NY, Philadelphia PA, Glen Burnie MD,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07213791

Phase1, Recruiting

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas

for
Bladder Cancer, Squamous Cell Carcinoma of the Lung,
Location: New Haven CT, New York NY, Philadelphia PA, Fairfax VA,
Sponsor: EvolveImmune United, Inc

Sex: All

Age: 18+

Code: NCT07217171

Phase1, Recruiting

ProofPrincip IntraTu TCells SinglDoseImmunCheckpoinInhib Gastro-Esophage Adenocarcinoma w/ARID1a Mu

for
Solid Tumor, Adult, Malignant Solid Tumor,
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT06824363

Early_phase1, Recruiting

Study of [177Lu]Lu-DWJ155 and [68Ga]Ga-DWJ155 in Patients With Solid Tumors

for
Breast Cancer, Non-small Cell Lung Cancer (NSCLC),
Location: Montreal, Omaha NE
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07660055

Phase1, Recruiting

A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors

for
Gastric or Gastro-esophageal Junction (GEJ) Adenocarcinoma,
Location: Lake Success NY, Hackensack NJ, Fairfax VA, Durham NC,
Sponsor: Astellas Pharma Global Development, Inc.

Sex: All

Age: 18+

Code: NCT07488676

Phase1, Phase2, Recruiting

EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors

for
Advanced Solid Tumors, MSI-H or dMMR Advanced Solid Tumors,
Location: Houston TX
Sponsor: Eikon Therapeutics

Sex: All

Age: 18+

Code: NCT07262619

Phase1, Phase2, Recruiting

The Vanguard Study: Testing a New Way to Screen for Cancer

for
Bladder Carcinoma, Breast Carcinoma, Colorectal Carcinoma,
Location: Portsmouth VA, Norfolk VA, Bethesda MD, Richmond VA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 45 - 70+

Code: NCT06995898

Recruiting