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Active & Responsive

The Effects of Bariatric Surgeries on Glucose Metabolism

for
Post Bariatric Surgery, Gastric Bypass, Sleeve Gastrectomy,
Location: San Antonio TX
Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All

Age: 18 - 65

Code: NCT02823665

Early_phase1, Recruiting
Active & Responsive

Selective TrkA Inhibitor VMD-928 to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

for
Head and Neck Carcinoma, Adenoid Cystic Carcinoma, Lung Cancer,
Location: Santa Rosa CA, Hartford CT, Washington D.C. DC,
Sponsor: VM Oncology, LLC

Sex: All

Age: 18 - 70+

Code: NCT03556228

Phase1, Recruiting
Active & Responsive

Cadisegliatin as Adjunctive Therapy to Insulin in Participants With Type 1 Diabetes

for
Diabetes Mellitus, Type 1
Location: Escondido CA, La Jolla CA, Englewood CO, Cooper City FL,
Sponsor: vTv Therapeutics

Sex: All

Age: 18+

Code: NCT06334133

Phase3, Recruiting
Active & Responsive

A Study to Investigate Safety and Tolerability of TransCon IL-2 β/γ Alone or in Combination With Pembrolizumab and/or TransCon TLR7/8 Agonist or Other Anticancer Therapies in Adult Participants With Locally Advanced or Metastatic Solid Tumor Malignancies

for
Advanced Solid Tumor, Locally Advanced Solid Tumor,
Location: Los Angeles CA, Springfield IL, Louisville KY,
Sponsor: Ascendis Pharma Oncology Division A/S

Sex: All

Age: 18+

Code: NCT05081609

Phase1, Phase2, Recruiting
Active & Responsive

Low-Dose Radiotherapy in Treating Painful Bone Metastases in Patients With Multiple Myeloma

for
Bone Pain, Metastatic Malignant Neoplasm in the Bone,
Location: Duarte CA, Los Angeles CA, Atlanta GA, Boston MA,
Sponsor: University of Southern California

Sex: All

Age: 18+

Code: NCT03858205

Recruiting

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Safety and Efficacy of Injectable Klotho Plasmid Gene Therapy in Humans

for
Healthy Adults
Location: Austin TX
Sponsor: Minicircle

Sex: All

Age: 23 - 70+

Code: NCT07216781

Phase1, Recruiting
New

A Gene Therapy Study of RP-A501 in Male Patients With Danon Disease

for
Danon Disease
Location: La Jolla CA, Boston MA, Philadelphia PA
Sponsor: Rocket Pharmaceuticals Inc.

Sex: Male

Age: 8+

Code: NCT06092034

Phase2, Recruiting
New

Gene Therapy for HER-Positive Cancer (SENTRY-HER2)

for
HER2 Expressing Solid Tumors
Location: Denver CO, Nashville TN
Sponsor: Vironexis Biotherapeutics Inc.

Sex: All

Age: 18+

Code: NCT07192432

Phase1, Phase2, Recruiting
New

Neuroimaging and Biomarkers of Neurotoxicity After Chimeric Antigen Receptor T-Cell Therapy

for
CAR T-Cell Therapy
Location: La Jolla CA
Sponsor: University of California, San Diego

Sex: All

Age: 18+

Code: NCT07075523

Recruiting
New

A Safety and Efficacy Long-Term Follow-up Study of Adult Participants Treated With Gene Modified T Cells

for
Long Term Safety Following GM T Cell Therapy
Location: Nashville TN
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06798298

Recruiting