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Predicting Responsiveness in Oncology Patients Based on Host Response Evaluation During Anti Cancer Treatments, Using Multiomics

for
Non Small Cell Lung Cancer, Healthy
Location: Dallas TX
Sponsor: OncoHost Ltd.

Sex: All

Age: 18+

Code: NCT05736029

Recruiting

Adjunctive Intravenous Ascorbic Acid for Advanced Non-Small Cell Lung Cancer

for
Lung Cancer
Location: Ottawa
Sponsor: The Canadian College of Naturopathic Medicine

Sex: All

Age: 18+

Code: NCT05849129

Phase2, Recruiting

Model to Predict pCR and IrAEs in Early Stage Non-small Cell Lung Cancer

for
Non-small Cell Lung Cancer Stage IB (Resectable),
Location: London
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Sex: All

Age: 18+

Code: NCT06250829

Recruiting

EQUAL: EGFR ctDNA QUantative Assessment for Lung Cancer Screening in Asian and Latinx Populations

for
Lung Cancer, EGFR Gene Mutation
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 40 - 70+

Code: NCT06716580

Recruiting

A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)

for
Non-small Cell Lung Cancer
Location: Halifax, Stamford CT, Trois-Rivieres, Albany NY,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06345729

Phase3, Recruiting

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Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy Protocols

for
Multiple Myeloma, Lymphoma, Non-Hodgkin,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT02682667

Recruiting

Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers

for
Pancreatic Ductal Adenocarcinoma, Non-small Cell Lung Cancer,
Location: Boston MA, Montreal, Toronto, Jacksonville FL,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT06562192

Phase1, Recruiting

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

for
Non Small Cell Lung Cancer, Glioma Glioblastoma Multiforme,
Location: Boston MA, New York NY, Washington D.C. DC, Fairfax VA,
Sponsor: Tango Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06810544

Phase1, Phase2, Recruiting

A Beta-only IL-2 ImmunoTherapY Study

for
Advanced Solid Tumor, Unresectable Solid Tumor,
Location: Boca Raton FL, Toronto, Detroit MI, Atlanta GA,
Sponsor: Medicenna Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05086692

Phase1, Phase2, Recruiting

PET/CT Changes During Chemoimmunotherapy and Radiation Therapy in Patients With Stage IV Non-small Cell Lung Cancer

for
Metastatic Lung Non-Small Cell Carcinoma,
Location: Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT04151940

Recruiting

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

for
Bladder Carcinoma, Ureter Carcinoma, Renal Pelvis Carcinoma,
Location: Lewiston ME, East Brunswick NJ, Philadelphia PA,
Sponsor: Guardant Health, Inc.

Sex: All

Age: 18+

Code: NCT05059444

Recruiting

Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies

for
Solid Tumor, Adult, Triple Negative Breast Cancer,
Location: Scottsdale AZ, La Jolla CA, Stanford CA
Sponsor: BioEclipse Therapeutics

Sex: All

Age: 18+

Code: NCT04282044

Phase1, Recruiting

Hyperpolarized 129-Xenon Imaging in Adult Hematopoietic Cell Transplant Recipients With Pulmonary Impairment

for
Pulmonary, Pneumonia, Hematopoietic System--Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05041140

Recruiting

Synapse 3D With Intravascular Indocyanine Green

for
Non-small Cell Lung Cancer, Primary Neoplasm
Location: Hamilton
Sponsor: St. Joseph's Healthcare Hamilton

Sex: All

Age: 18+

Code: NCT03953144

Phase1, Phase2, Recruiting

A Study of Lorlatinib in Advanced ALK and ROS1 Rearranged Lung Cancer With CNS Metastasis in the Absence of Measurable Extracranial Lesions

for
Non-Small Cell Lung Cancer (NSCLC)
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT02927340

Phase2, Recruiting

EBUS-TBNA vs Transbronchial Mediastinal Cryobiopsy for Adequacy of Next Generation Sequencing

for
Lung Cancer
Location: Nashville TN
Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All

Age: 18+

Code: NCT06105801

Recruiting

Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: New York NY, Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT06518057

Phase2, Recruiting

Using Urine Samples to Identify Lung Cancer

for
Non Small Cell Lung Cancer
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18 - 70+

Code: NCT06033248

Recruiting

Adding Certolizumab to Chemotherapy + Nivolumab in People Who Have Lung Cancer That Can Be Treated With Surgery

for
Lung Cancer, Lung Cancer Stage II, Lung Cancer Stage III
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT04991025

Phase2, Recruiting

Concurrent Chemotherapy Plus HFR Radiation Therapy in Inoperable NSCLC

for
Non-small Cell Lung Cancer
Location: Syracuse NY
Sponsor: State University of New York - Upstate Medical University

Sex: All

Age: 18+

Code: NCT02619448

Early_phase1, Recruiting