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Adjuvant Chemotherapy and Immunotherapy for Completely Resected Small Cell Lung Cancer

for
Small Cell Lung Cancer (SCLC)
Location: Boston MA, Charlottesville VA, Chicago IL
Sponsor: Alliance Foundation Trials, LLC.

Sex: All

Age: 18+

Code: NCT07149363

Phase2, Recruiting

A Study to Assess the Safety and Tolerability of BMS-986525 Alone and in Combination Therapy in Participants With Relapsed/Refractory Small Cell Lung Cancer

for
Relapsed/Refractory Small Cell Lung Cancer
Location: Durham NC, Cleveland OH, Detroit MI, Nashville TN
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07325136

Phase1, Phase2, Recruiting

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

for
Renal Cell Carcinoma (RCC),
Location: Boston MA, New Haven CT, New York NY, Hackensack NJ,
Sponsor: Exelixis

Sex: All

Age: 18+

Code: NCT05176483

Phase1, Recruiting

A Study of Intismeran Autogene (V940)/Placebo + Pembrolizumab and Chemotherapy in Metastatic Squamous Non-Small Cell Lung Cancer (V940-013)

for
Squamous Non-small Cell Lung Cancer
Location: Paramus NJ, Albany NY, Fairfax VA, Tampa FL,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07221474

Phase2, Recruiting

Study of Sacituzumab Govitecan With Atezolizumab/Durvalumab as Maintenance Therapy for Extensive-Stage Small Cell Lung Cancer

for
Small Cell Lung Cancer ( SCLC ),
Location: Detroit MI
Sponsor: Bindu R Potugari

Sex: All

Age: 18+

Code: NCT07339059

Phase2, Recruiting

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Prophylactic Anti-Seizure Medication vs No Anti-Seizure Medication for Patients With Primary Motor Cortex Brain Metastases

for
Seizures, Primary Motor Cortex,
Location: Boston MA
Sponsor: Ayal A. Aizer, MD

Sex: All

Age: 18+

Code: NCT07130786

Phase2, Recruiting

Stereotactic Radiation for Growing/Changing Brain Metastases With Same-Day Radiation Planning and Treatment With Margin Reduction

for
Brain Metastases, Adult, Brain Tumor - Metastatic,
Location: Boston MA
Sponsor: Ayal A. Aizer, MD

Sex: All

Age: 18+

Code: NCT07132190

Phase2, Recruiting

EZH2 Inhibitor, Tulmimetostat, and PD-1 Blockade for Treatment of Advanced Non-small Cell Lung Cancer

for
Non Small Cell Lung Cancer
Location: Ann Arbor MI, Houston TX, San Diego CA
Sponsor: VA Office of Research and Development

Sex: All

Age: 18+

Code: NCT05467748

Phase1, Phase2, Recruiting

Targeted Telerehabilitation Following Curative Intent Therapy of Lung Cancer

for
Lung Cancer, Cancer Survivors
Location: Aurora CO
Sponsor: VA Office of Research and Development

Sex: All

Age: 18+

Code: NCT05179408

Recruiting

A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)

for
Small-cell Lung Cancer
Location: New Haven CT, Stony Brook NY, The Bronx NY, Broomall PA,
Sponsor: Zai Lab (Shanghai) Co., Ltd.

Sex: All

Age: 18+

Code: NCT07218146

Phase3, Recruiting

An External Control Arm Study in Non-Small Cell Lung Cancer

for
Non Small Cell Lung Cancer
Location: Milford DE, Dover DE, Elk Grove IL, Rolling Meadows IL,
Sponsor: N-Power Medicine

Sex: All

Age: 18+

Code: NCT07174388

Recruiting

A Study to Evaluate the Safety, Pharmacokinetics and Efficacy of TJ101 in Patients With Advanced/Metastatic Solid Tumors

for
Lung Cancer (NSCLC), Prostate Cancer, Esophageal Cancer,
Location: Orlando FL, Nashville TN, Houston TX
Sponsor: Phrontline Biopharma

Sex: All

Age: 18+

Code: NCT07181473

Phase1, Recruiting

Symbiotic-Lung-04: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Extensive-Stage Small Cell Lung Cancer

for
Small Cell Lung Cancer (SCLC)
Location: Virginia Beach VA, Norfolk VA, Chesapeake VA,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07226999

Phase2, Phase3, Recruiting

Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies (ELEPHAS-05)

for
Cancer, Immunotherapy, Advanced Solid Tumors Cancer,
Location: Frederick MD, St Louis MO, Springfield MO,
Sponsor: Elephas

Sex: All

Age: 18+

Code: NCT07327489

Recruiting

A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies

for
Advanced Solid Malignancies, Non-small Cell Lung Cancer (NSCLC),
Location: Baltimore MD, Fairfax VA, Toronto, San Antonio TX,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07223047

Phase1, Phase2, Recruiting

Promoting Immunotherapy Efficacy With Low-Dose Liver RT

for
Low-Dose Liver Radiation (LD-LRT), Non Small Cell Lung Cancer,
Location: Cincinnati OH
Sponsor: Jordan Kharofa

Sex: All

Age: 18+

Code: NCT07225036

Recruiting

A Study of PT0511 in Participants With KRAS Mutated or Amplified Advanced Solid Tumors

for
Colorectal Cancer, Pancreatic Cancer,
Location: Boston MA, Fairfax VA, San Antonio TX,
Sponsor: PAQ Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07300150

Phase1, Recruiting

Sample Collection for Ongoing Research and Product Evaluation Study

for
Breast Cancer, Lung Cancer, Muscle Invasive Bladder Cancer,
Location: Austin TX
Sponsor: Natera, Inc.

Sex: All

Age: 18+

Code: NCT07318051

Recruiting

Study of NXP900 With Osimertinib in Subjects With Advanced, EGFR-Mutated Non-Small Cell Lung Cancer

for
EGFR Mutation Positive Non-small Cell Lung Cancer,
Location: Calverton MD, Fairfax VA, Pittsburgh PA, Houston TX,
Sponsor: Nuvectis Pharma, Inc.

Sex: All

Age: 18+

Code: NCT07315113

Phase1, Recruiting

Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer

for
Non-small Cell Lung Cancer
Location: Stony Brook NY, Lake Success NY, Rego Park NY,
Sponsor: Canadian Cancer Trials Group

Sex: All

Age: 18+

Code: NCT06686771

Phase3, Recruiting