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Prospective External Control Cohort In Patients With Newly Diagnosed Advanced or Metastatic EGFR Mutant Non-Small Cell Lung Cancer

for
Non Small Cell Lung Cancer
Location: Milford DE, Dover DE, Elk Grove Village IL, Houston TX,
Sponsor: N-Power Medicine

Sex: All

Age: 18+

Code: NCT07028489

Recruiting

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

for
Metastatic Solid Tumor, Recurrent Solid Tumor,
Location: Boston MA, New York NY, Cleveland OH, Grand Rapids MI,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT06465069

Phase1, Recruiting

Diclofenac for the Treatment of Patients With Metastatic Non-small Cell Lung Cancer on Single Agent Immunotherapy

for
Advanced Lung Non-Small Cell Carcinoma,
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT06731270

Phase2, Recruiting

Trabedersen (OT-101) With Pembrolizumab for Newly Diagnosed Advanced NSCLC and Positive PD-L1

for
Non-small Cell Lung Cancer
Location: Omaha NE
Sponsor: University of Nebraska

Sex: All

Age: 19+

Code: NCT06579196

Phase1, Phase2, Recruiting

AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

for
Solid Tumor Cancer, Locally Advanced, Metastatic Solid Tumors,
Location: Washington D.C. DC, Sarasota FL, Atlanta GA, Houston TX,
Sponsor: Avenzo Therapeutics, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07038343

Phase1, Phase2, Recruiting

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Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

for
PDAC, PDAC - Pancreatic Ductal Adenocarcinoma, NSCLC,
Location: Boston MA, New York NY, Washington D.C. DC, Fairfax VA,
Sponsor: Tango Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06922591

Phase1, Phase2, Recruiting

First-in-human Study of Interferon-y PET Imaging to Assess Response to Immunotherapy

for
Non Small Cell Lung Cancer
Location: Detroit MI
Sponsor: Nerissa T. Viola

Sex: All

Age: 18+

Code: NCT06439914

Phase1, Recruiting

A Multinational Study Assessing an Oral EGFR Inhibitor, DZD6008 in Patients Who Have Advanced NSCLC With EGFR Mutations (TIAN-SHAN1)

for
Non Small Cell Lung Cancer
Location: New York NY
Sponsor: Dizal Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06905197

Phase1, Recruiting

Zelenectide Pevedotin in NECTIN4 Amplified Advanced or Metastatic Non-small Cell Lung Cancer

for
Non-Small Cell Lung Cancer
Location: Boston MA, Philadelphia PA, Arlington VA, Fairfield OH,
Sponsor: BicycleTx Limited

Sex: All

Age: 18+

Code: NCT06933329

Phase2, Recruiting

[212Pb]VMT-Alpha-NET in Metastatic or Inoperable Somatostatin-Receptor Positive Gastrointestinal Neuroendocrine Tumors, Pheochromocytoma/Paragangliomas, Small Cell Lung, Renal Cell, and Head and Neck Cancers

for
Sinonasal Neuroendocrine Carcinoma, Nasopharyngeal Carcinoma,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06479811

Phase1, Recruiting

Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant BPD Through Exercise

for
Chronic Lung Disease, Chronic Obstructive Pulmonary Disease,
Location: Minneapolis MN
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 8 - 25

Code: NCT05025774

Recruiting

Integrated Cancer Repository for Cancer Research

for
Pancreatic Cancer, Thyroid Cancer, Lung Cancer,
Location: Manchester CT, Holyoke MA, Glens Falls NY, Utica NY,
Sponsor: University of Nebraska

Sex: All

Age: 19 - 70+

Code: NCT02012699

Recruiting

Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors

for
Melanoma, Medullary Thyroid Cancer,
Location: Tucson AZ, Seattle WA
Sponsor: University of Arizona

Sex: All

Age: 18 - 70+

Code: NCT06814496

Phase1, Phase2, Recruiting

Signature Development and Validation Protocol for an Epigenetic Assay in Diagnosing Lung Cancer

for
Lung Cancer, Lung Cancer Screening, Healthy Volunteers (HV),
Location: Glen Burnie MD
Sponsor: University of Maryland, Baltimore

Sex: All

Age: 18+

Code: NCT07008664

Recruiting

A Study Evaluating Neoadjuvant Chemoimmunotherapy With Immunosensitizing Radiation for Borderline Resectable Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer
Location: Bel Air MD, Glen Burnie MD, Baltimore MD
Sponsor: University of Maryland, Baltimore

Sex: All

Age: 18+

Code: NCT06800339

Phase1, Recruiting

GT103 in Combination With Pembrolizumab for the Treatment of Advanced or Metastatic STK11 Mutant Non-Small Cell Lung Cancer

for
Advanced Lung Non-Small Cell Carcinoma,
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT07017829

Phase2, Recruiting

Lung Cancer Screening of Family Members of Patients With Mutation-Driven Lung Cancer

for
Lung Cancer, Driver Mutation
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18 - 70+

Code: NCT07062172

Recruiting

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

for
Pancreatic Ductal Adenocarcinoma, Non Small Cell Lung Cancer,
Location: Boston MA, New York NY, Philadelphia PA, Baltimore MD,
Sponsor: Verastem, Inc.

Sex: All

Age: 18+

Code: NCT07020221

Phase1, Phase2, Recruiting

The Impact of Surgical Technique on Circulating Tumor DNA in Stage I-III Non-Small Cell Lung Cancer

for
Lung Non-Small Cell Carcinoma, Stage I Lung Cancer AJCC v8,
Location: Abington PA, Philadelphia PA, Willow Grove PA
Sponsor: Thomas Jefferson University

Sex: All

Age: 18+

Code: NCT05502523

Recruiting

Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Irvine CA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06910761

Phase2, Recruiting