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Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies

for
Soft-tissue Sarcoma, Triple Negative Breast Cancer,
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT07064018

Phase1, Phase2, Recruiting

Evaluation of the Safety and Efficacy of Abenacianine (VGT-309) to Identify Cancer in Subjects Undergoing Surgery for Cancer in the Lung

for
Lung Cancer, Lung Metastases
Location: Philadelphia PA, Orlando FL, Ann Arbor MI, Rochester MN,
Sponsor: Vergent Bioscience, Inc.

Sex: All

Age: 18+

Code: NCT07499674

Phase3, Recruiting

A Clinical Study of Gocatamig (MK-6070) and Infinatamab Deruxtecan (MK-2400) in People With Small Cell Lung Cancer (MK-6070-003)

for
Small Cell Lung Cancer Extensive Stage
Location: Hackensack NJ, Charlottesville VA, Orlando FL,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07227597

Phase1, Phase2, Recruiting

A Mobile Patient Health Technology Intervention for Improving Lung Cancer Screening Rates in Eligible High Risk Patients

for
Lung Cancer
Location: Winston-Salem NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 50 - 70+

Code: NCT07322367

Recruiting

A Phase 1 Study of EPI-326 in EGFR-mutant NSCLC and HNSCC

for
Epidermal Growth Factor, Epidermal Growth Factor Receptor,
Location: Lake Success NY, East Brunswick NJ, Nashville TN,
Sponsor: EpiBiologics

Sex: All

Age: 18+

Code: NCT07462377

Phase1, Recruiting

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A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors

for
Melanoma, Non-small Cell Lung Cancer,
Location: Fairfax VA, Pittsburgh PA, Grand Rapids MI, St Louis MO,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07115043

Phase1, Phase2, Recruiting

University of Michigan COPD Identification Through Lung Cancer Screening Cohort Study - MAP2

for
COPD (Chronic Obstructive Pulmonary Disease),
Location: Ann Arbor MI
Sponsor: University of Michigan

Sex: All

Age: 50 - 70+

Code: NCT07482475

Recruiting

Evaluate the Clinical Performance of the Flow Cytometry - FlowPath Lung Test as a Sensitive and Specific Non-invasive Diagnostic of Sputum Samples to Identify/Detect the Presence of Lung Cancer in High-risk Individuals Who Have Existing Lung Nodules, 6 to <30 mm in Diameter, Determined by LDCT.

for
Lung Cancer (Diagnosis)
Location: Miami FL, DuBois PA, Tampa FL, Bay Pines FL, Dayton OH,
Sponsor: bioAffinity Technologies Inc.

Sex: All

Age: 50 - 70+

Code: NCT07168993

Recruiting

Beamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD Mutations

for
Non-small Cell Lung Cancer
Location: Boston MA, New York NY, Fairfax VA, Orange City FL,
Sponsor: Boehringer Ingelheim

Sex: All

Age: 18+

Code: NCT07195695

Phase3, Recruiting

A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

for
Non-small Cell Carcinoma, Non-Small Cell Lung Cancer Metastatic,
Location: Quebec, White Plains NY, The Bronx NY, Belleville NJ,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07144280

Phase3, Recruiting

IDOV-Immune for Advanced Solid Tumors

for
Colorectal Cancer, Pancreatic Cancer, Melanoma, Ovarian Cancer,
Location: St Louis MO, Houston TX, San Antonio TX
Sponsor: ViroMissile, Inc.

Sex: All

Age: 18+

Code: NCT06910657

Phase1, Recruiting

Symbiotic-Lung-20: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers

for
Advanced/Metastatic Non-Small Cell Lung Cancer,
Location: Neptune City NJ, The Bronx NY, Teaneck NJ,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07227298

Phase1, Phase2, Recruiting

Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion

for
Mesothelioma, Non Small Cell Lung Cancer,
Location: Brookline MA, Port Jefferson Station NY, Mineola NY,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT05245500

Phase1, Recruiting

A Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma

for
Metastatic Castration Resistant Prostate Cancer (mCRPC),
Location: Myrtle Beach SC, Nashville TN, Omaha NE, Irving TX,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT03460977

Phase1, Recruiting

RAPA-201 Therapy of Solid Tumors

for
Solid Tumor, Small Cell and Non-small Cell Lung Cancer,
Location: Hackensack NJ
Sponsor: Rapa Therapeutics LLC

Sex: All

Age: 18+

Code: NCT05144698

Phase1, Phase2, Recruiting

Assessment of a Radiomics-based Computer-Aided Diagnosis Tool for Pulmonary nodulES

for
Lung Cancer, Pulmonary Nodule, Solitary
Location: Philadelphia PA
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All

Age: 35 - 70+

Code: NCT05968898

Recruiting

Adapting the Tumor Board Model for Mental Illness and Cancer

for
Cancer, Severe Major Depression, Schizophrenia,
Location: Danvers MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT05837598

Recruiting

Hyperthermia/Thermal Therapy With Chemotherapy to Treat Inoperable or Metastatic Tumors

for
Neuroendocrine Cancer, Small Cell Lung Cancer,
Location: Houston TX
Sponsor: The University of Texas Health Science Center, Houston

Sex: All

Age: 18+

Code: NCT00178698

Phase2, Recruiting

GI-101/GI-101A as a Single Agent or in Combination With Pembrolizumab or Lenvatinib in Advanced Solid Tumors

for
Advanced Solid Tumor, Metastatic Solid Tumor, Cervical Cancer,
Location: New York NY, Huntersville NC
Sponsor: GI Innovation, Inc.

Sex: All

Age: 18+

Code: NCT04977453

Phase1, Phase2, Recruiting

Local Consolidative Therapy and Durvalumab for Oligoprogressive and Polyprogressive Stage III NSCLC After Chemoradiation and Anti-PD-L1 Therapy

for
Stage III Lung Cancer AJCC v8,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04892953

Phase2, Recruiting