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Beating Lung Cancer in Ohio Protocol in Improving Survival in Patients With Stage IV Non-Small Cell Lung Cancer

for
Cigarette Smoker, Current Smoker, Lung Adenocarcinoma,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT03199651

Recruiting

Marathon of Hope Cancer Centres Network Study for Ontario (MOHCCN-O)

for
Breast Cancer, Colorectal Cancer, Pancreas Cancer,
Location: Kingston, Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT05403177

Recruiting

Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer

for
Endocrine Tumors, Non-Small Cell Lung Cancer, Ovarian Cancer,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT03412877

Phase2, Recruiting

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

for
Endometrial Cancer, Cervical Cancer, Ovarian Cancer,
Location: Boston MA, Mineola NY, New York NY, East Brunswick NJ,
Sponsor: SystImmune Inc.

Sex: All

Age: 18+

Code: NCT06293898

Phase1, Recruiting

A Study of Alisertib in Patients With Extensive Stage Small Cell Lung Cancer

for
Small Cell Lung Cancer
Location: Boston MA, Baltimore MD, Washington D.C. DC, Fairfax VA,
Sponsor: Puma Biotechnology, Inc.

Sex: All

Age: 18+

Code: NCT06095505

Phase2, Recruiting

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Fluorine-18-AlphaVBeta6-Binding Peptide Positron Emission Tomography in Metastatic Non-Small Cell Lung Cancer

for
Lung Cancer, Lung Cancer Metastatic, Brain Metastases,
Location: Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18+

Code: NCT05452005

Phase1, Recruiting

Phase Ib Study of the Safety of T-DXd and Immunotherapy Agents With and Without Chemotherapy in Advanced or Metastatic HER2+, Non-squamous NSCLC

for
Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Location: Montreal, Baltimore MD, Fairfax VA, Houston TX,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT04686305

Phase1, Recruiting

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

for
Oncology, Breast Cancer, Prostate Cancer, Gynecologic Cancer,
Location: Toronto, Pittsburgh PA, Milwaukee WI, Houston TX
Sponsor: UMC Utrecht

Sex: All

Age: 18+

Code: NCT04075305

Recruiting

FiH Study to Investigate Safety, PK and Efficacy of the NaPi2b ADC TUB-040 in Patients With PROC or r/r Adenocarcinoma NSCLC

for
Ovarian Cancer, Non-small Cell Lung Cancer
Location: New York NY, East Brunswick NJ, Fairfax VA, Columbus OH,
Sponsor: Tubulis GmbH

Sex: All

Age: 18+

Code: NCT06303505

Phase1, Phase2, Recruiting

This is a Phase 1 Trial of ZM008, an Anti-LLT1 Antibody, Used as Single Agent Followed by Combination Treatment With Toripalimab in Patients With Advanced Solid Tumors

for
Non Small Cell Lung Cancer,
Location: Boston MA, Austin, TX 78758 TX, San Antonio TX
Sponsor: Zumutor Biologics Inc.

Sex: All

Age: 18+

Code: NCT06451497

Phase1, Recruiting

Prospective Collection of Whole Blood From Active Non-Small Cell Lung Cancer Patients for Supplemental Research

for
Non Small Cell Lung Cancer
Location: Waltham MA
Sponsor: Sanguine Biosciences

Sex: All

Age: 18 - 70+

Code: NCT05669105

Recruiting

Investigating the Effects of Atezolizumab in People Whose Tumour DNA or RNA Indicates Possible Sensitivity

for
Breast Cancer, Lung Cancer, Gastrointestinal Cancer,
Location: Vancouver
Sponsor: British Columbia Cancer Agency

Sex: All

Age: 18+

Code: NCT04273061

Phase2, Recruiting

Phase I/IIa Study of H002 in NSCLC With Active EGFR Mutation

for
Non-small Cell Lung Cancer
Location: Boston MA, New York NY, Fairfax VA, Los Angeles CA
Sponsor: RedCloud Bio

Sex: All

Age: 18+

Code: NCT05519293

Phase1, Phase2, Recruiting

A Open-label Prospective Cohort Trial of Curcumin Plus Tyrosine Kinase Inhibitors (TKI) for EGFR -Mutant Advanced NSCLC

for
Lung Cancer
Location: Montreal
Sponsor: Lady Davis Institute

Sex: All

Age: 18+

Code: NCT02321293

Phase1, Recruiting

Preliminary Efficacy of Different Exercise Training During Immunotherapy in Patients With Lung Cancer: The ENHANCE Trial

for
Lung Cancer
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT06026111

Recruiting

Bexarotene, Tretinoin, and Combination Chemotherapy in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer

for
Lung Cancer
Location: Lakewood CA
Sponsor: Raghu Nandan, M.D., Inc

Sex: All

Age: 18+

Code: NCT00514293

Phase2, Recruiting

Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell Lung Cancer (LS-SCLC)

for
Limited-stage Small Cell Lung Cancer (LS-SCLC)
Location: Bethesda MD, Orange City FL, Toledo OH, Grand Rapids MI,
Sponsor: Shanghai Junshi Bioscience Co., Ltd.

Sex: All

Age: 18+

Code: NCT06095583

Phase3, Recruiting

Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer

for
Non-small Cell Lung Cancer
Location: New Haven CT, Brooklyn NY, New York NY, Montreal,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06350097

Phase3, Recruiting

Personalized Accelerated ChEmoRadiation (PACER) for Lung Cancer

for
Lung Cancer
Location: San Jose CA, Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 18+

Code: NCT06080061

Phase1, Recruiting

Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

for
Non-Small Cell Lung Cancer
Location: St. John's, Rimouski, Boston MA, Levis, Stony Brook NY,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06357533

Phase3, Recruiting