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Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

for
Non-Small Cell Lung Cancer (NSCLC), Colorectal Cancer,
Location: Boston MA, New York NY, Fairfax VA, Pittsburgh PA,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT06128551

Phase1, Phase2, Recruiting

A Study of Mental Health Care in People With Cancer

for
Breast Cancer, Colorectal Cancer, Lung Cancer, Prostate Cancer
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 65+

Code: NCT06037954

Recruiting

Pan-Canadian Lung Cancer Observational Study (PALEOS)

for
Lung Cancer
Location: Brampton
Sponsor: William Osler Health System

Sex: All

Age: 18+

Code: NCT04706754

Recruiting

Mobile Application to Improve Health-Related Outcomes in Patients With Advanced Lung Cancer

for
Lung Cancer
Location: Boston MA, Los Angeles CA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT06427954

Recruiting

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

for
Breast Cancer, Gastric Cancer, Esophageal Cancer,
Location: New York NY, Nashville TN, Houston TX, Dallas TX,
Sponsor: Jazz Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06695845

Phase2, Recruiting

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Phase 1 Study of OP-3136 in Advanced or Metastatic Solid Tumors

for
Advanced or Metastatic ER+ HER2- Breast Cancer (mBC),
Location: Boston MA, Sarasota FL, Grand Rapids MI, Nashville TN,
Sponsor: Olema Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT06784193

Phase1, Recruiting

Tempus Small Cell Lung Cancer Observational Study (Sculptor)

for
Small Cell Lung Cancer
Location: Baltimore MD, York PA, Chapel Hill NC, Columbus OH,
Sponsor: Tempus AI

Sex: All

Age: 18+

Code: NCT05257551

Recruiting

Studying Tumor Tissue Samples and Blood Samples to Learn More About DNA Changes in Patients With Lung Cancer

for
Lung Cancer
Location: Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18+

Code: NCT00899405

Recruiting

A Study Comparing Chemotherapy Dosing Based on Either Standard Body Surface Area or Lean Body Mass in Patients With Advanced Lung Cancer

for
Lung Cancer
Location: Edmonton
Sponsor: AHS Cancer Control Alberta

Sex: All

Age: 18+

Code: NCT01624051

Phase2, Recruiting

Stereotactic Magnetic Resonance Guided Radiation Therapy

for
Pancreas Cancer, Lung Cancer, Renal Cancer, Adrenal Metastases,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT04115254

Recruiting

Safety of Pentoxifylline and Vitamin E With Stereotactic Ablative Radiotherapy (SABR) in Non-small Cell Lung Cancers

for
Non-small Cell Lung Cancers
Location: Louisville KY
Sponsor: University of Louisville

Sex: All

Age: 18+

Code: NCT01871454

Phase2, Recruiting

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC

for
Non-squamous Non-small Cell Lung Cancer
Location: Saint John, South Portland ME, West Haven CT,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06627647

Phase3, Recruiting

Trial of Therapeutic Cancer Vaccine OSE2101 in Patients With Non-Small Cell Lung Cancer and Secondary Resistance to Immune Checkpoint Inhibitor

for
Patients With Non-Small Cell Lung Cancer
Location: Rimouski, Worcester MA, Norwich CT, Patchogue NY,
Sponsor: OSE Immunotherapeutics

Sex: All

Age: 18+

Code: NCT06472245

Phase3, Recruiting

A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

for
Advanced Non-small Cell Lung Cancer, HER2 Mutation
Location: Montreal, Fort Lauderdale FL, Toronto, Pittsburgh PA,
Sponsor: Bayer

Sex: All

Age: 18+

Code: NCT06452277

Phase3, Recruiting

A Study of Pembrolizumab With or Without Chemotherapy in Combination With Additional Treatments for Advanced Non-Small Cell Lung Cancer (NSCLC) (MK-3475-01G/KEYMAKER U01)

for
Non-small Cell Lung Cancer
Location: Philadelphia PA, Baltimore MD, Lexington KY, Fargo ND,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06731907

Phase2, Recruiting

Liver SBRT in Combination With Immune Checkpoint Inhibition in Patients With Metastatic Non-small Cell Lung Cancer

for
Liver Metastases, Non-small Cell Lung Cancer
Location: Ann Arbor MI
Sponsor: VA Ann Arbor Healthcare System

Sex: All

Age: 18+

Code: NCT05430009

Phase1, Recruiting

A Study of IBI363 in Subjects with Advanced Solid Malignancies

for
Melanoma, Non-small Cell Lung Cancer, Colorectal Cancer,
Location: Plantation FL, Ocala FL, Dearborn MI, Troy MI,
Sponsor: Innovent Biologics (Suzhou) Co. Ltd.

Sex: All

Age: 18+

Code: NCT06281678

Phase2, Recruiting

Stereotactic Ablative Radiotherapy (SABR) for the Treatment of Patients With Metastatic Cancer, ID-COMET Trial

for
Oligometastasis, Lung Cancer, Colo-rectal Cancer,
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 1+

Code: NCT06563388

Phase3, Recruiting

A Study of Sotorasib in People With Non-Small Cell Lung Cancer

for
Non Small Lung Cancer
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06582771

Phase2, Recruiting

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

for
Non-small Cell Lung Cancer (NSCLC), Colorectal Cancer (CRC),
Location: Boston MA, New York NY, Baltimore MD, Fairfax VA,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT05379985

Phase1, Phase2, Recruiting