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A Study of Zipalertinib in Patients With Advanced Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions or Other Uncommon Mutation.

for
Advanced or Metastatic NSCLC Harboring Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion (ex20ins) Mutations,
Location: Boston MA, Commack NY, Uniondale NY, Harrison NY,
Sponsor: Taiho Oncology, Inc.

Sex: All

Age: 18+

Code: NCT05967689

Phase2, Recruiting

Immune Profile Selection By Fraction of ctDNA in Patients With Advanced NSCLC Treated With Immunotherapy

for
Carcinoma, Non-Small-Cell Lung
Location: Hackensack NJ
Sponsor: Hackensack Meridian Health

Sex: All

Age: 18+

Code: NCT05715229

Phase2, Recruiting

A Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors

for
Cancer, Cancer, Lung
Location: Lebanon NH, Philadelphia PA, Fairfax VA, Toronto,
Sponsor: Conjupro Biotherapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05948865

Phase1, Recruiting
Active & Responsive

Transmission and Acquisition of Nontuberculous Mycobacteria Outbreak Investigation (TrANsMIt)

for
Nontuberculous Mycobacterial Pulmonary Infection,
Location: Chapel Hill NC
Sponsor: University of North Carolina, Chapel Hill

Sex: All

Age: 0 - 70+

Code: NCT06155747

Recruiting

First in Human Study of TUB-030 in Patients With Advanced Solid Tumors

for
Advanced Solid Tumors, HNSCC, SCLC, NSCLC,
Location: Boston MA, New York NY, New Haven CT, Miami FL, Toronto,
Sponsor: Tubulis GmbH

Sex: All

Age: 18+

Code: NCT06657222

Phase1, Phase2, Recruiting

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A2 to O Lung Transplants

for
Lung Transplant, ABO Incompatibility
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT05581745

Recruiting

The Role of Circadian Clock Proteins in Innate and Adaptive Immunity

for
Pneumonia, Necrotizing Soft Tissue Infection,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18 - 65

Code: NCT03482245

Recruiting

A Study of Venoarterial ECMO vs Off-Pump Bilateral Orthotopic Lung Transplantation

for
Lung Transplant
Location: Philadelphia PA, Baltimore MD, Columbus OH,
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT05547698

Recruiting

Prospective Urban Rural Epidemiology Study

for
Cardiovascular Diseases, Risk Factor, Cardiovascular,
Location: Quebec City, Ottawa, Hamilton, Vancouver
Sponsor: Population Health Research Institute

Sex: All

Age: 35 - 70

Code: NCT03225586

Recruiting

Capnography in the Post-Anesthesia Care Unit (PACU)

for
Obstructive Sleep Apnea, Bariatric Surgery Candidate,
Location: Tampa FL
Sponsor: University of South Florida

Sex: All

Age: 18+

Code: NCT03076047

Recruiting

A Global Phase III Study of Rilvegostomig or Pembrolizumab Monotherapy for First-Line Treatment of PD-L1-high Metastatic Non-small Cell Lung Cancer

for
Carcinoma, Non-Small Cell Lung
Location: Westbury NY, Fresh Meadows NY, Philadelphia PA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06868277

Phase3, Recruiting

Walking After Surgery to Improve Recovery and Outcomes After Surgery, AIRTECH Study

for
Lung Carcinoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04783168

Recruiting

A Study of ZL-1310 in Subjects With Small Cell Lung Cancer

for
SCLC
Location: New Haven CT, Hackensack NJ, Fairfax VA, Durham NC,
Sponsor: Zai Lab (Shanghai) Co., Ltd.

Sex: All

Age: 18+

Code: NCT06179069

Phase1, Recruiting

Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

for
Carcinoma, Non-Small-Cell Lung
Location: Westbrook ME, Worcester MA, Hartford CT, New York NY,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT06890598

Phase3, Recruiting

Pentastarch Use in Cardiac Surgery

for
Cardiac Surgery, Cardiopulmonary Bypass
Location: Hamilton
Sponsor: Hamilton Health Sciences Corporation

Sex: All

Age: 0+

Code: NCT00182377

Recruiting

Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors

for
Ovarian Cancer, Lung Adenocarcinoma, Endometrial Cancer,
Location: Boston MA, Providence RI, Montreal, Fairfax VA, Toronto,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT05797168

Phase1, Phase2, Recruiting

Using Biomarkers for Diagnosis, Risk Stratification of Post -Treatment Recurrence and Long-Term Surveillance of Lung Cancer

for
Lung; Node, Adenocarcinoma of Lung
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT05665504

Recruiting

Ipatasertib and Docetaxel in Metastatic NSCLC Patients Who Have Failed 1st Line Immunotherapy

for
NSCLC Stage IV, NSCLC Stage IIIB
Location: Kansas City KS, Fairway KS
Sponsor: Jun Zhang, MD, PhD

Sex: All

Age: 18+

Code: NCT04467801

Phase2, Recruiting

Pembrolizumab (MK-3475) Plus Investigational Agents in Resectable Non-small Cell Lung Cancer (NSCLC) (MK-3475-01E/KEYMAKER-U01)

for
Lung Neoplasm Malignant
Location: Baltimore MD, Fairfax VA, Daphne AL, Tyler TX,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06788912

Phase2, Recruiting

Combination of Atezolizumab and Pirfenidone in Second-line and Beyond NSCLC

for
NSCLC Stage IV, NSCLC, Recurrent
Location: Kansas City KS
Sponsor: University of Kansas Medical Center

Sex: All

Age: 18+

Code: NCT04467723

Phase1, Phase2, Recruiting