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Inotuzumab Ozogamicin Post-Transplant For Acute Lymphocytic Leukemia

for
Acute Lymphocytic Leukemia
Location: Boston MA, Cleveland OH, Columbus OH, Omaha NE
Sponsor: Leland Metheny

Sex: All

Age: 16 - 70+

Code: NCT03104491

Phase1, Phase2, Recruiting

Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma

for
Recurrent Astrocytoma, IDH-Mutant, Grade 3,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06815029

Phase1, Recruiting

Uterine Preservation Via Lifestyle Transformation

for
Endometrial Hyperplasia, Grade 1 Endometrial Cancer
Location: St Louis MO, Oklahoma City OK, Albuquerque NM
Sponsor: Washington University School of Medicine

Sex: Female

Age: 18+

Code: NCT05903131

Phase2, Recruiting

Study of MGUS, Smoldering Myeloma, Early MDS and CLL to Assess Molecular Events of Progression and Clinical Outcome

for
Monoclonal Gammopathy of Undetermined Significance (MGUS),
Location: Weymouth MA, Boston MA, Brighton MA, Methuen MA,
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT02269592

Recruiting

Autologous CD22 CAR T Cells Following Commercial CD19 CAR T Cells in B Cell Malignancies

for
Leukemia, Acute Lymphoblastic Leukemia
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 1 - 25

Code: NCT06408194

Phase1, Recruiting

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Phase I/II Trial: Engineered Donor Graft (Orca Q) for Pediatric Hematopoietic Cell Transplant (HCT)

for
Acute Myeloid Leukemia, Acute Lymphoid Leukemia,
Location: Gainesville FL
Sponsor: University of Florida

Sex: All

Age: 0 - 50

Code: NCT05322850

Phase1, Phase2, Recruiting

Transcutaneous Auricular Vagus Nerve Stimulation for Insomnia in Survivors of Childhood Acute Lymphoblastic Leukemia

for
Survivor of Childhood Cancer, Insomnia,
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 20 - 50

Code: NCT07191119

Recruiting

Thiotepa-based Conditioning Regimen With De-escalated Post-graft Cyclophosphamide for Allogeneic Stem Cell Transplantation in Hematologic Malignancies

for
Acute Lymphocytic Leukemia (ALL), Acute Myeloid Leukemia (AML),
Location: Pittsburgh PA
Sponsor: Sawa Ito, MD

Sex: All

Age: 18+

Code: NCT07565220

Phase1, Recruiting

Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas

for
Anaplastic Oligodendroglioma, Astrocytoma, IDH-Mutant, Grade 3,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT07468136

Phase1, Phase2, Recruiting

BZLF1 Peptide Vaccine (OSU-2131) With QS-21 for the Prevention of Epstein-Barr Virus Related Cancer in Patients Awaiting Solid Organ Transplants

for
Chronic Kidney Disease, Stage 4,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18 - 65

Code: NCT06741072

Phase1, Recruiting

Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma

for
Astrocytoma, IDH-Mutant, Grade 2,
Location: New Haven CT, Trumbull CT, Mineola NY, New York NY,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06860594

Phase1, Recruiting

Wearable Sensory Prosthesis to Improve Coordination, Walking, and Physical Activity

for
Peripheral Neuropathy With Type 2 Diabetes,
Location: Jacksonville FL
Sponsor: RxFunction Inc.

Sex: All

Age: 60+

Code: NCT07554443

Recruiting

Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for Advanced Brain Cancer

for
Astrocytoma, IDH-Mutant, Grade 3
Location: Bath ME, Portland ME, Scarborough ME, Sanford ME,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 12+

Code: NCT07215910

Phase3, Recruiting

Study of Chemotherapy-Free Induction Regimen for Ph+ Acute Lymphoblastic Leukemia With Inotuzumab Ozogamicin (InO)

for
Lymphoblastic Leukemia, Acute Lymphoblastic Leukemia,
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT04747912

Phase2, Recruiting

CD22 CAR T-cells to Extend Remission Following Commercial CD19 CAR T-cells in Children, Adolescents, and Adults With Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia

for
Acute Lymphoblastic Leukemia, B-All
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 3 - 65

Code: NCT07328503

Phase2, Recruiting

Optimizing Health Related Quality of Life Measurement in Adolescent and Young Adult Oncology

for
Malignant Solid Neoplasm, Hematopoietic Neoplasms,
Location: Winston-Salem NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 15+

Code: NCT06897137

Recruiting

Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

for
B Acute Lymphoblastic Leukemia
Location: Boston MA, Providence RI, New Haven CT, Lake Success NY,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18 - 39

Code: NCT03150693

Phase3, Recruiting

A Phase 1/2 Study of TRI-611 in ALK-Positive NSCLC

for
ALK-positive NSCLC, ALK-Positive Lung Cancer,
Location: Boston MA, New York NY, Fairfax VA, Durham NC,
Sponsor: TRIANA Biomedicines, Inc.

Sex: All

Age: 18+

Code: NCT07491497

Phase1, Phase2, Recruiting

Resistance Exercise and Incretin Mimetic for Cardiometabolic Health in Survivors of ALL With Obesity

for
Acute Lymphoblastic Leukemia, Obesity
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 18+

Code: NCT07228741

Phase2, Recruiting

BAL Fluid Biomarkers in Sarcoma

for
Soft Tissue Sarcoma (STS), Bronchoalveolar Lavage (BAL),
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT06815666

Phase2, Recruiting